Onartuzumab (anti-MET) - Primary antibody, for ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) various applications, specific to MET, >95%, Human IgG1, Antibody of MET proto-oncogene; receptor tyrosine kinase, Antibody of MET proto-oncogene; receptor tyrosine kinase

CAS: 1133766-06-9 Cat. No.: Ab170687
Disponible para pedir
GRADE & PURITY Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. ≥95%(SDS-PAGE&SEC-HPLC) See COA
Application
Animal Model, ELISA, Flow Cytometry, Functional Assay
Host species
Human
Reactive species
Cynomolgus monkey, Human, Mouse
Isotype
Human IgG1
Conjugation
Unconjugated
 ·  off list, applied to all prices below.
Size
Estado
Price
Qty
100μg
Ab170687-100μg
10
148,90US$
1mg
Ab170687-1mg
3
743,90US$
5mg
Ab170687-5mg
1
2.679,90US$
10mg
Ab170687-10mg
1-2 wks(?)
Item is derived from our semi-finished stock and is processed in 1-2 weeks.
4.019,90US$
Enter a quantity for the sizes you want to add.
🧪

Why this grade

Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA Animal Free,Azide Free,Carrier Free,ExactAb™,Low Endotoxin,Recombinant,Validated for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -80°C,Avoid repeated freezing and thawing Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 2 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Descripción general

Onartuzumab (anti-MET) is a unique, humanized and affinity-matured monovalent (one-armed) monoclonal antibody against the MET receptor. Onartuzumab (anti-MET) potently inhibits HGF binding and receptor phosphorylation and signaling. Onartuzumab (anti-MET) has antibody-like pharmacokinetics and antitumor activity.
Purity
>95% (SDS-PAGE&SEC)
Endotoxin Level
< 1.0EU/mg

Specifications

Product Name
Onartuzumab (anti-MET) - Primary antibody, for ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) various applications, specific to MET, >95%, Human IgG1, Antibody of MET proto-oncogene; receptor tyrosine kinase
Sinónimos
Onartuzumab | MetMAb | Anti-HGFR / c-Met Reference Antibody (onartuzumab) | AUTS9 antibody | c met antibody | D249 antibody | Hepatocyte growth factor receptor antibody | HGF antibody | HGF receptor antibody | HGF/SF receptor antibody | HGFR antibody | ME
Especificaciones y pureza
Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Especies hospedadoras
Human
Especificidad
MET
Aplicación
ELISA, Functional Assay, Flow cytometry, Kinetics (BLI), Kinetics (SPR)
Conjugación
Unconjugated
Grado
Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Tipo de acción
ANTAGONIST
Mecanismo de acción
Antibody of MET proto-oncogene; receptor tyrosine kinase
Tipo de anticuerpo
Primary antibody
Clonalidad
Recombinant
Isotipo
Human IgG1
Tipo de cadena ligera
kappa
SDS-PAGE
99.15 kDa
Método de purificación
Protein A purified
Pureza
>95%
Fuente
CHO supernatant
Concentración
See COA
CAS
1133766-06-9
Almacenamiento y envío
Forma
Liquid
Condiciones de almacenamiento de almacenamiento
Store at -80°C,Avoid repeated freezing and thawing
Enviado en
Dry ice packs + Cold packs
Estabilidad y almacenamiento
Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
Imágenes

Onartuzumab (anti-MET) (Ab170687) - Flow Cytometry
Flow Cytometry analysis of Jurkat cells labelling MET (red) with Onartuzumab (anti-MET) (Ab170687). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

Onartuzumab (anti-MET) (Ab170687) - SEC
The purity of Onartuzumab (anti-MET) (Ab170687) is more than 95% verified by HPLC.

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Objetivos asociados (humanos)
MET Tclin Hepatocyte growth factor receptor (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
Mecanismos de acción
Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

5 results found

Lot NumberCertificate TypeFechaArticulo
ZJ24F0911265Certificate of AnalysisJul 09, 2026 Ab170687
ZJ24F0911266Certificate of AnalysisJul 09, 2026 Ab170687
ZJ24F0911267Certificate of AnalysisJul 09, 2026 Ab170687
ZJ23F1001505Certificate of AnalysisNov 02, 2023 Ab170687
ZJ23F1001506Certificate of AnalysisNov 02, 2023 Ab170687
Citations of This Product
Referencias
1. Lianbao Ye, Yuanxin Tian, Zhonghuang Li, Hong Jin, Zhengguang Zhu, Shanhe Wan, Junyan Zhang, Pengjiu Yu, Jiajie Zhang, Shuguang Wu.  (2012)  Design, synthesis and molecular docking studies of some novel spiro[indoline-3, 4′-piperidine]-2-ones as potential c-Met inhibitors.  EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY,      [PMID:22381355] [10.1016/j.ejmech.2012.02.016]
2. Lianbao Ye, Xiaomin Ou, Yuanxin Tian, Bangwei Yu, Yan Luo, Binghong Feng, Hansen Lin, Jiajie Zhang, Shuguang Wu.  (2013)  Indazoles as potential c-met inhibitors: Design, synthesis and molecular docking studies.  EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY,      [PMID:23702473] [10.1016/j.ejmech.2013.04.004]
Calculadoras de soluciones
Reseñas

Reseñas de cliente

Need help choosing the grade?

Our grade selection guide covers purity, stabilizer status, and application suitability for all variants in our catalog.

View Animal Free grade guide → View Carrier Free grade guide → View Recombinant grade guide → View Validated grade guide → View ExactAb™ grade guide → View Low Endotoxin grade guide → View Azide Free grade guide →

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