GRADE & PURITYRecombinant?Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin.Validated?Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated.ExactAb™?ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications.See COA
Recombinant, ExactAb™, Validated, See COA ExactAb™,Recombinant,Validated for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping
Store at -20°C,Avoid repeated freezing and thawing Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
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Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Descripción general
Rabbit anti Human LXR alpha Antibody, Recombinant, could be used for WB, IF/ICC and so on.
Application:
WB: 1/1000-1/2000 IF/ICC: 1/50-1/200
Protein Function:
Orphan receptor. Interaction with RXR shifts RXR from its role as a silent DNA-binding partner to an active ligand-binding subunit in mediating retinoid responses through target genes defined by LXRES. LXRES are DR4-type response elements characterized by direct repeats of two similar hexanuclotide half-sites spaced by four nucleotides. Plays an important role in the regulation of cholesterol homeostasis, regulating cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR and LRP8.
Specifications
Product Name
Recombinant LXR alpha Antibody - Primary antibody, specific to NR1H3, Rabbit IgG
Sinónimos
alpha | Liver X receptor alpha | liver X receptor-alpha | LXR alpha | LXRA | NR1H3 | Nuclear receptor subfamily 1 group H member 3 | nuclear receptor subfamily 1, group H, member 3 | oxysterols receptor LXR-alpha | RLD-1 | Liver X receptor alpha antibody
Especificaciones y pureza
Recombinant, ExactAb™, Validated, See COA
Especies hospedadoras
Rabbit
Especificidad
NR1H3
Inmunógeno
A synthetic peptide derived from human NR1H3 (AA 50-100)
Control positivo
WB: Jurkat, Hep G2, MCF7, NIH/3T3 and C6 cell lysates. IF/ICC: HeLa cells.
Conjugación
Unconjugated
Grado
ExactAb™, Recombinant, Validated
Isotipo
Rabbit IgG
Tipo de cadena ligera
kappa
SDS-PAGE
150 kDa
Método de purificación
Protein A purified
Concentración
See COA
Almacenamiento y envío
Forma
Liquid
Condiciones de almacenamiento de almacenamiento
Store at -20°C,Avoid repeated freezing and thawing
Enviado en
Ice chest + Ice pads
Estabilidad y almacenamiento
Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
Imágenes
Recombinant LXR alpha Antibody (Ab113743)- Western Blot All lanes: Recombinant LXR alpha Antibody (Ab113743) at 1/2000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/30000 dilution
Predicted band size: 50 kDa Observed band size: 48, 95 kDa Heterodimer of NR1H3 and RXR (retinoic acid receptor). Interacts with CCAR2 (via N-terminus) in a ligand-independent manner. Interacts with SIRT1 and this interaction is inhibited by CCAR2 (PMID: 25661920). Exposure time: 15.6 s
Recombinant LXR alpha Antibody (Ab113743) - IF/ICC Immunofluorescent analysis of HeLa cells, using Recombinant LXR alpha Antibody (Ab113743) at 1/50 dilution.
Recombinant LXR alpha Antibody (Ab113743) - IF/ICC Immunofluorescent analysis of HeLa cells, using Recombinant LXR alpha Antibody (Ab113743) at 1/50 dilution.
Recombinant LXR alpha Antibody (Ab113743) - IF/ICC Immunofluorescent analysis of HeLa cells, using Recombinant LXR alpha Antibody (Ab113743) at 1/150 dilution.
Aplicación
Aplicación
Dilution info
IF/ICC
1/50 - 1/200
WB
1/1000-1/2000
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
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