Insulin from porcine pancreas, CAS No.12584-58-6

CAS: 12584-58-6 Cat. No.: I113907 Molecular Weight: 5777.54 EC Number: 235-703-3 PubChem CID: 16131098
AVAILABLE TO ORDER
GRADE & PURITY ≥27 USP units/mg
Accession #
P01317
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
10mg
I113907-10mg
3
$56.90
50mg
I113907-50mg
3
$141.90
100mg
I113907-100mg
2
$232.90
250mg
I113907-250mg
2
$462.90
1g
I113907-1g
2
$1,289.90
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Why this grade

≥27 USP units/mg for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 23 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Product Name
Insulin from porcine pancreas, CAS No.12584-58-6
Synonyms
DTXSID60154957
Specifications & Purity
≥27 USP units/mg
Biochemical and Physiological Mechanisms
Two-chain polypeptide hormone produced by the β-cells of pancreatic islets. Its molecular weight is ~5800 Da. The α and β chains are joined by two interchain disulfide bonds. The α chain contains an intrachain disulfide bond. Insulin regulates the cellula
Accession #
CAS
12584-58-6
Molecule Type
Protein
Storage and Shipping
Concentration
≥27 USP units/mg
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

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🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

3D Structure
Interactive Chemical Structure Model





Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

29 results found

Lot NumberCertificate TypeDateItem
C2626389Certificate of AnalysisMar 14, 2026 I113907
C2626390Certificate of AnalysisMar 14, 2026 I113907
C2626391Certificate of AnalysisMar 14, 2026 I113907
C2626392Certificate of AnalysisMar 14, 2026 I113907
C2626387Certificate of AnalysisMar 14, 2026 I113907
F1805054Certificate of AnalysisJan 27, 2026 I113907
H2505395Certificate of AnalysisJul 29, 2025 I113907
H2512598Certificate of AnalysisJul 29, 2025 I113907
H2512594Certificate of AnalysisJul 29, 2025 I113907
H2505396Certificate of AnalysisJul 29, 2025 I113907
H2505394Certificate of AnalysisJul 29, 2025 I113907
D2507547Certificate of AnalysisMar 29, 2025 I113907
G2404501Certificate of AnalysisMar 08, 2024 I113907
G2404502Certificate of AnalysisMar 08, 2024 I113907
H2421120Certificate of AnalysisOct 27, 2023 I113907
F2516134Certificate of AnalysisOct 27, 2023 I113907
E2529185Certificate of AnalysisOct 27, 2023 I113907
E2512031Certificate of AnalysisOct 27, 2023 I113907
K2303261Certificate of AnalysisOct 27, 2023 I113907
K2303260Certificate of AnalysisOct 27, 2023 I113907
K2303205Certificate of AnalysisOct 27, 2023 I113907
K2303212Certificate of AnalysisOct 27, 2023 I113907
K2303218Certificate of AnalysisOct 27, 2023 I113907
K2303220Certificate of AnalysisOct 27, 2023 I113907
K2303243Certificate of AnalysisOct 27, 2023 I113907
I2321517Certificate of AnalysisSep 12, 2023 I113907
I2321516Certificate of AnalysisSep 12, 2023 I113907
I2321515Certificate of AnalysisSep 12, 2023 I113907
L2423549Certificate of AnalysisMay 21, 2021 I113907

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Citations of This Product
References
1. Xiang Chen, Xiaojie Dou, Wei Qiu, Yichuan Hong, Yifan Chen.  (2023)  A glucose-sensitive microgel operating at physiological conditions for glucose detecting and insulin delivery.  EUROPEAN POLYMER JOURNAL,      [PMID:] [10.1016/j.eurpolymj.2023.112236]
2. Yangyang Lu, Haojie Yu, Li Wang, Di Shen, Jian Liu.  (2023)  Preparation of phenylboronic acid‐based glucose-responsive hydrogels and microneedles for regulated delivery of insulin.  EUROPEAN POLYMER JOURNAL,      [PMID:] [10.1016/j.eurpolymj.2023.112061]
3. Yu Wang, Haojie Yu, Li Wang, Jian Hu, Jingyi Feng, Di Shen, Yichuan Hong, Jinyi Liu, Dingning Chen.  (2023)  Microneedles with Two-Stage Glucose-Sensitive Controlled Release for Long-Term Insulin Delivery.  ACS Biomaterials Science & Engineering,      [PMID:37027835] [10.1021/acsbiomaterials.3c00137]
4. Xiang Chen, Haojie Yu, Li Wang, Di Shen, Bilal ul Amin, Jingyi Feng, Qian Zhang, Wei Xiong.  (2021)  Microneedle Patch Prepared from a Hydrogel by a Mild Method for Insulin Delivery.  ChemNanoMat,  (11): (1230-1240).  [PMID:] [10.1002/cnma.202100288]
5. Di Shen, Haojie Yu, Li Wang, Xiang Chen, Jingyi Feng, Qian Zhang, Wei Xiong, Jin Pan, Yin Han, Xiaowei Liu.  (2021)  Biodegradable phenylboronic acid-modified ε-polylysine for glucose-responsive insulin delivery via transdermal microneedles.  Journal of Materials Chemistry B,  (30): (6017-6028).  [PMID:34259305] [10.1039/D1TB00880C]
6. Yuhuan Li, Qingyang Zhang, Guanshen Cui, Fang Zhao, Xin Tian, Bao-Fa Sun, Ying Yang, Wei Li.  (2020)  m6A Regulates Liver Metabolic Disorders and Hepatogenous Diabetes.  GENOMICS PROTEOMICS & BIOINFORMATICS,      [PMID:33160098] [10.1016/j.gpb.2020.06.003]
7. Xiang Chen, Haojie Yu, Li Wang, Nan Wang, Qian Zhang, Weibin Zhou, Md Alim Uddin.  (2020)  Preparation of phenylboronic acid-based hydrogel microneedle patches for glucose-dependent insulin delivery.  JOURNAL OF APPLIED POLYMER SCIENCE,  138  (5): (49772).  [PMID:] [10.1002/app.49772]
8. Guohua Jiang, Bin Xu, Jiangying Zhu, Yang Zhang, Tianqi Liu, Gao Song.  (2019)  Polymer microneedles integrated with glucose-responsive mesoporous bioactive glass nanoparticles for transdermal delivery of insulin.  Biomedical Physics & Engineering Express,  (4): (045038).  [PMID:] [10.1088/2057-1976/ab3202]
9. Bassam Saif, Wenxin Zhang, Xu Zhang, Quan Gu, Peng Yang.  (2019)  Sn-Triggered Two-Dimensional Fast Protein Assembly with Emergent Functions.  ACS Nano,      [PMID:31244042] [10.1021/acsnano.9b01392]
10. Fang Tan, Zhifang Wang, Yan Yang, Xiaoxue Xie, Xinyi Hua, Xiumei Yang, Haowen Huang.  (2019)  Facile preparation of peroxidase-like core-shell nanorods and application as platform for colorimetric determination of glucose, insulin and glucose/insulin ratio.  TALANTA,      [PMID:31357295] [10.1016/j.talanta.2019.06.005]
11. Kunhua Lin, Juzhen Yi, Xuhong Mao, Hao Wu, Li-Ming Zhang, Liqun Yang.  (2019)  Glucose-sensitive hydrogels from covalently modified carboxylated pullulan and concanavalin A for smart controlled release of insulin.  REACTIVE & FUNCTIONAL POLYMERS,      [PMID:] [10.1016/j.reactfunctpolym.2019.01.016]
12. Xixi Song, Hongchao Jiao, Jingpeng Zhao, Xiaojuan Wang, Hai Lin.  (2018)  Dexamethasone and insulin stimulate ghrelin secretion of broilers in a different way.  GENERAL AND COMPARATIVE ENDOCRINOLOGY,      [PMID:30016627] [10.1016/j.ygcen.2018.07.009]
13. Na Wen, Shaoyu Lü, Chunmei Gao, Xiubin Xu, Xiao Bai, Can Wu, Piao Ning, Mingzhu Liu.  (2017)  Glucose-responsive zwitterionic dialdehyde starch-based micelles with potential anti-phagocytic behavior for insulin delivery.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2017.10.096]
14. Bin Xu, Guohua Jiang, Weijiang Yu, Depeng Liu, Yang Zhang, Junyi Zhou, Shiqing Sun, Yongkun Liu.  (2017)  H2O2-Responsive mesoporous silica nanoparticles integrated with microneedle patches for the glucose-monitored transdermal delivery of insulin.  Journal of Materials Chemistry B,  (41): (8200-8208).  [PMID:32264463] [10.1039/C7TB02082A]
15. Na Wen, Chunmei Gao, Shaoyu Lü, Xiubin Xu, Xiao Bai, Can Wu, Piao Ning, Shaofei Zhang, Mingzhu Liu.  (2017)  Novel amphiphilic glucose-responsive modified starch micelles for insulin delivery.  RSC Advances,  (73): (45978-45986).  [PMID:] [10.1039/C7RA08291F]
16. Weijiang Yu, Guohua Jiang, Yang Zhang, Depeng Liu, Bin Xu, Junyi Zhou.  (2017)  Polymer microneedles fabricated from alginate and hyaluronate for transdermal delivery of insulin.  Materials Science & Engineering C-Materials for Biological Applications,      [PMID:28866156] [10.1016/j.msec.2017.05.143]
17. Bin Xu, Guohua Jiang, Weijiang Yu, Depeng Liu, Yongkun Liu, Xiangdong Kong, Juming Yao.  (2017)  Preparation of poly(lactic-co-glycolic acid) and chitosan composite nanocarriers via electrostatic self assembly for oral delivery of insulin.  Materials Science & Engineering C-Materials for Biological Applications,      [PMID:28576004] [10.1016/j.msec.2017.04.113]
18. Xiangxiang Du, Guohua Jiang, Lei Li, Wentong Yang, Hua Chen, Yongkun Liu, Qin Huang.  (2015)  Preparation of glucose-sensitive and fluorescence micelles via a combination of photoinitiated polymerization and chemoenzymatic transesterification for the controlled release of insulin.  JOURNAL OF APPLIED POLYMER SCIENCE,  133  (9):   [PMID:] [10.1002/app.43026]
19. Yu Wang, Haojie Yu, Li Wang, Lei Zhang, Jian Yang, Chenguang Ouyang, Jian Hu, Jingyi Feng, Zheng Deng, Chang Chen.  (2025)  A customized partitioned microneedle array based on functionalized glycol chitosan for prolonged blood glucose regulation and prevention of diabetic neuropathy.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:40096930] [10.1016/j.ijbiomac.2025.142163]
20. Xinyi Zhang, Yuelian Zhang, Huishan Zheng, Xue Yang, Shiqi Zou, Jianmin Chen.  (2024)  Design, fabrication, and evaluation of antimicrobial sponge microneedles for the transdermal delivery of insulin.  EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS,      [PMID:39613270] [10.1016/j.ejpb.2024.114586]
21. Yu Wang, Haojie Yu, Li Wang, Lei Zhang, Jinyi Liu, Dingning Chen, Jian Yang, Chenguang Ouyang, Jian Hu, Jingyi Feng, Chengjiang Li.  (2024)  Intelligent microneedle patch based on functionalized alginate and chitosan for long-term self-regulated insulin delivery.  CARBOHYDRATE POLYMERS,      [PMID:39567163] [10.1016/j.carbpol.2024.122885]
22. Biying Zhang, Taoxun Zhou, Runxin Zhu, Peixi Qin, Juncheng Li, Chunqun Wang, Hui Liu, Min Hu.  (2025)  Aptazyme-mediated gene regulation in Strongyloides stercoralis for functional studies of insulin receptor isoform specificity.  PLoS Pathogens,  21  (12): (e1013774).  [PMID:41406115] [10.1371/journal.ppat.1013774]
23. Xinyi Zhang, Huishan Zheng, Yuelian Zhang, Xue Yang, Nan Jin, Qiulong Zhang, Jianmin Chen.  (2025)  Design, fabrication, and evaluation of antimicrobial sponge-hydrogel bilayer microneedles: An integrated system for transdermal insulin delivery and glucose sensing.  Biomaterials Advances,      [PMID:41475034] [10.1016/j.bioadv.2025.214693]
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