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Tyrosine-protein kinase fes/fps (FES)

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  1. AMG-900, Serine/threonine-protein kinase Aurora inhibitor
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    AMG-900, Serine/threonine-protein kinase Aurora inhibitor
    CAS: 945595-80-2 EC Number: 188-123-7 Formula: C28H21N7OS Molecular Weight: 503.58
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: A129924
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    Technical Identifiers
    IUPAC Name
    N-[4-[3-(2-aminopyrimidin-4-yl)pyridin-2-yl]oxyphenyl]-4-(4-methylthiophen-2-yl)phthalazin-1-amine
    SMILES
    CC1=CSC(=C1)C2=NN=C(C3=CC=CC=C32)NC4=CC=C(C=C4)OC5=C(C=CC=N5)C6=NC(=NC=C6)N
    InChIKey
    IVUGFMLRJOCGAS-UHFFFAOYSA-N
    InChI
    1S/C28H21N7OS/c1-17-15-24(37-16-17)25-20-5-2-3-6-21(20)26(35-34-25)32-18-8-10-19(11-9-18)36-27-22(7-4-13-30-27)23-12-14-31-28(29)33-23/h2-16H,1H3,(H,3show more
    Synonyms
    PM-671 | GTPL8060 | AMG900 | AMG-900 | DTXSID90241526 | HMS3656H17 | NCGC00263094-01 | 1-PHTHALAZINAMINE, N-(4-((3-(2...
  2. Lorlatinib - Moligand™, ≥98%(HPLC) CAS No(1454846-35-5) P167337 by Aladdin Scientific
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    Lorlatinib, EML4-ALK inhibitor
    CAS: 1454846-35-5 EC Number: 813-704-5 PubChem CID: 71731823 Formula: C21H19FN6O2 Molecular Weight: 406.41
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    In Stock Item #: P167337
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    Technical Identifiers
    IUPAC Name
    (16R)-19-amino-13-fluoro-4,8,16-trimethyl-9-oxo-17-oxa-4,5,8,20-tetrazatetracyclo[16.3.1.02,6.010,15]docosa-1(22),2,5,10(15),11,13,18,20-octaene-3-carshow more
    SMILES
    CC1C2=C(C=CC(=C2)F)C(=O)N(CC3=NN(C(=C3C4=CC(=C(N=C4)N)O1)C#N)C)C
    InChIKey
    IIXWYSCJSQVBQM-LLVKDONJSA-N
    InChI
    1S/C21H19FN6O2/c1-11-15-7-13(22)4-5-14(15)21(29)27(2)10-16-19(17(8-23)28(3)26-16)12-6-18(30-11)20(24)25-9-12/h4-7,9,11H,10H2,1-3H3,(H2,24,25)/t11-/m1/show more
    Synonyms
    (10R)-7-Amino-12-fluoro-2,10,16-trimethyl-15-oxo-10,15,16,17-tetrahydro-2H-4,8-methenopyrazolo(4,3-h)(2,5,11)benzoxad...
  3. AMG-900, Serine/threonine-protein kinase Aurora inhibitor
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    AMG-900, Serine/threonine-protein kinase Aurora inhibitor
    CAS: 945595-80-2 EC Number: 188-123-7 Formula: C28H21N7OS Molecular Weight: 503.58
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    In Stock Item #: A409137
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    Technical Identifiers
    Synonyms
    N-(4-(3-(2-aminopyrimidin-4-yl)pyridin-2-yloxy)phenyl)-4-(4-methylthiophen-2-yl)phthalazin-1-amine
  4. Lorlatinib (PF-6463922), EML4-ALK inhibitor
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    Lorlatinib (PF-6463922), EML4-ALK inhibitor
    CAS: 1454846-35-5 EC Number: 813-704-5 PubChem CID: 71731823 Formula: C21H19FN6O2 Molecular Weight: 406.41
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    In Stock Item #: L409078
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    Technical Identifiers
    Synonyms
    (10R)-7-amino-12-fluoro-10,15,16,17-tetrahydro-2,10,16-trimethyl-15-oxo-2H-4,8-methenopyrazolo[4,3-h][2,5,11]benzoxad...
  6. TAK1/MAP4K2 inhibitor 1
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    TAK1/MAP4K2 inhibitor 1
    CAS: 1315330-11-0 PubChem CID: 71254032 Formula: C29H31F3N6O2 Molecular Weight: 552.59
    ≥98%
    Out of Stock Item #: T648184
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    Technical Identifiers
    IUPAC Name
    N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-4-methyl-3-[(6-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)oxy]benzamide
    SMILES
    CCN1CCN(CC1)CC2=C(C=C(C=C2)NC(=O)C3=CC(=C(C=C3)C)OC4=NC=NC5=C4C=C(N5)C)C(F)(F)F
    InChIKey
    RWNAOXLCVXJMGM-UHFFFAOYSA-N
    InChI
    1S/C29H31F3N6O2/c1-4-37-9-11-38(12-10-37)16-21-7-8-22(15-24(21)29(30,31)32)36-27(39)20-6-5-18(2)25(14-20)40-28-23-13-19(3)35-26(23)33-17-34-28/h5-8,13show more
    Synonyms
    AKOS016012030 | n-(4-((4-ethylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)-4-methyl-3-((6-methyl-7h-pyrrolo[2,3-...
  8. TL02-59
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    TL02-59
    CAS: 1315330-17-6 PubChem CID: 71254350 Formula: C32H34F3N5O4 Molecular Weight: 609.64
    ≥99%
    Out of Stock Item #: T651668
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    Technical Identifiers
    IUPAC Name
    3-(6,7-dimethoxyquinazolin-4-yl)oxy-N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-4-methylbenzamide
    SMILES
    CCN1CCN(CC1)CC2=C(C=C(C=C2)NC(=O)C3=CC(=C(C=C3)C)OC4=NC=NC5=CC(=C(C=C54)OC)OC)C(F)(F)F
    InChIKey
    AMHWQBGAKJESFB-UHFFFAOYSA-N
    InChI
    1S/C32H34F3N5O4/c1-5-39-10-12-40(13-11-39)18-22-8-9-23(15-25(22)32(33,34)35)38-30(41)21-7-6-20(2)27(14-21)44-31-24-16-28(42-3)29(43-4)17-26(24)36-19-3show more
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