Nicotinamide riboside chloride( NR-CL) - ≥99.5% , CAS No.23111-00-4

CAS: 23111-00-4 Cat. No.: N1492503 Molecular Weight: 290.7 EC Number: 807-820-5

GRADE & PURITY ≥99.5%

Storage

Protected from light,Store at -20°C

Shipped In

Ice chest + Ice pads

Overview

Nicotinamide riboside is involved in nicotinate and nicotinamide metabolism. Nicotinamide riboside was originally identified as a nutrient in milk and later discovered to be a NAD(+) precursor.

Specifications

Specifications & Purity

≥99.5%

Storage

Protected from light, Store at -20°C

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥99.5%

Names and Identifiers

• Canonical Smiles: C1=CC(=C[N+](=C1)C2C(C(C(O2)CO)O)O)C(=O)N.[Cl-]
• IUPAC Name: 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyridin-1-ium-3-carboxamide;chloride
• InChIKey: YABIFCKURFRPPO-IVOJBTPCSA-N
• INCHI: 1S/C11H14N2O5.ClH/c12-10(17)6-2-1-3-13(4-6)11-9(16)8(15)7(5-14)18-11;/h1-4,7-9,11,14-16H,5H2,(H-,12,17);1H/t7-,8-,9-,11-;/m1./s1
• Isomeric SMILES: C1=CC(=C[N+](=C1)[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O)C(=O)N.[Cl-]
• Molecular Weight: 290.7
• Reaxy-Rn: 48663754
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=48663754&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic oxygen compounds
    • Class Organooxygen compounds
      • Subclass Carbohydrates and carbohydrate conjugates
        • Level5 Glycosyl compounds
          • Level6 Glycosylamines

• Kingdom: Organic compounds
• Superclass: Organic oxygen compounds
• Class: Organooxygen compounds
• Subclass: Carbohydrates and carbohydrate conjugates
• Intermediate Tree Nodes: Glycosyl compounds
• Direct Parent: Glycosylamines
• Alternative Parents: Pentoses Nicotinamides Pyridinium derivatives Vinylogous amides Heteroaromatic compounds Oxolanes Secondary alcohols Primary carboxylic acid amides Azacyclic compounds Oxacyclic compounds Organic oxides Organic chloride salts Primary alcohols Hydrocarbon derivatives Organic zwitterions Organonitrogen compounds
• Molecular Framework: Aromatic heteromonocyclic compounds
• Substituents: N-glycosyl compound - Pentose monosaccharide - Nicotinamide - Pyridine carboxylic acid or derivatives - Monosaccharide - Pyridine - Pyridinium - Vinylogous amide - Heteroaromatic compound - Oxolane - Secondary alcohol - Carboxamide group - Primary carboxylic acid amide - Organoheterocyclic compound - Oxacycle - Azacycle - Carboxylic acid derivative - Organic salt - Hydrocarbon derivative - Primary alcohol - Organonitrogen compound - Organic oxide - Alcohol - Organic nitrogen compound - Organic chloride salt - Organic zwitterion - Aromatic heteromonocyclic compound
• Description: This compound belongs to the class of organic compounds known as glycosylamines. These are compounds consisting of an amine with a beta-N-glycosidic bond to a carbohydrate, thus forming a cyclic hemiaminal ether bond (alpha-amino ether).
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Sensitivity: Moisture sensitive；Heat sensitive；light sensitive
• Molecular Weight: 290.700 g/mol
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 3
• Exact Mass: 290.067 Da
• Monoisotopic Mass: 290.067 Da
• Topological Polar Surface Area: 117.000 Ų
• Heavy Atom Count: 19
• Formal Charge: 0
• Complexity: 314.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 4
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 2

XLogP3

References

1. Seongsu Kang, Jiwon Park, Eunbyul Cho, Dohyun Kim, Sanghyun Ye, Eui Taek Jeong, Seung-Hyun Jun, Nae-Gyu Kang.  (2025)  Distinctive Gene Expression Profiles and Biological Responses of Skin Fibroblasts to Nicotinamide Mononucleotide: Implications for Longevity Effects on Skin.  Biomedicines,  13  (10): (2395).  [PMID:41153679] [10.3390/biomedicines13102395]

2. Yi Zhang, Ying Guo, Wenxi He, Yaping Zhao, Zhaode Feng, Mengjiao Shi, Xinyan Li, Liangwen Yan, Jiayi Xu, Kailing Hu, Rongrong Liu, Yinggang Zhang, Gang Wang, Hao Li, Pengfei Liu.  (2025)  Deciphering the rules of disulfidptosis: a genome-wide signature for identifying disulfidptosis-related genes and analyzing hepatocellular carcinoma chemotherapy sensitivities.  FREE RADICAL BIOLOGY AND MEDICINE,      [PMID:41138962] [10.1016/j.freeradbiomed.2025.10.278]