Eosinophilic Leukemia Detection Laboratory

Summary

Blood picture: white blood cell count is obviously increased, up to (500-20O)×109/L, all stages of sclerophilic granulocytes are obviously increased, and continuously increased, most of them are as high as 60% (20-90%) or more, the absolute value is more than 1.5 ×109/L, there are often vacuoles formed in the cells, few and coarse granules, primitive and early juvenile granulocytes are rare, there are usually Hemoglobin and erythrocyte count were reduced, and platelet count was decreased. This experiment is from Mudanjiang Medical College, undergraduate 5-year laboratory guide for testing majors.

Operation method

Eosinophilic Leukemia Detection Laboratory

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Blood picture: white blood cell count is obviously increased, up to (500-20O) ×109/L, all stages of sclerophilic granulocytes are obviously increased, and continuously increased, most of them are as high as 60% (20-90%) or more, the absolute value is more than 1.5 ×109/L, there are often vacuoles formed in the cells, few and coarse granules, primitive and early juvenile granulocytes are rare, there are usually Hemoglobin and erythrocyte count are reduced, and thrombocytopenia.

Bone marrow image: the bone marrow is extremely active or obviously active. Eosinophilic granulocytes are increased, there are various stages of naive eosinophils, there may be leukemic cleavage phenomenon, nuclear left shift and morphological abnormalities, and the number of progranulocytes is more than 5%. Some people categorize this disease into three types:

(1) primitive cell type: that is, there are primitive granulocytes and eosinophils in the blood and bone marrow.

(2) Naïve cell type: mainly naïve eosinophils with neutrophilia. This type of disease progresses slowly.

(3) Mature cell type: mature eosinophils are increased, with abnormal morphology, large and few granules, uneven distribution, and many eosinophils. Uneven distribution, many basophilic granules, cytoplasmic vacuoles, nuclear foliation.


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Categories: Protocols

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