1,4,8,11-Tetraazacyclotetradecane - ≥98% , CAS No.295-37-4

CAS: 295-37-4 Cat. No.: T130042 Molecular Weight: 200.32 Beilstein Registry Number: 111811 EC Number: 206-039-1 PubChem CID: 64964
AVAILABLE TO ORDER
GRADE & PURITY ≥98%
Synonyms
Cyclam
Storage
Store at 2-8°C,Argon charged
Shipped In
Wet ice
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
250mg
T130042-250mg
3

$9.90

$14.90
Save $5.00 (33.56%)
1g
T130042-1g
2

$11.90

$17.90
Save $6.00 (33.52%)
5g
T130042-5g
1

$56.90

$85.90
Save $29.00 (33.76%)
10g
T130042-10g
1

$98.90

$148.90
Save $50.00 (33.58%)
25g
T130042-25g
1

$244.90

$367.90
Save $123.00 (33.43%)
100g
T130042-100g
2

$968.90

$1,453.90
Save $485.00 (33.36%)
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Why this grade

≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at 2-8°C,Argon charged Ships Wet ice Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 2 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

1,4,8,11-Tetraazacyclotetradecane is an azamacrocycle that forms more stable metal complexes as compared to open chain ligands.

Specifications

Synonyms
Cyclam
Specifications & Purity
≥98%
Storage
Store at 2-8°C, Argon charged
Shipped In
Wet ice
This product requires cold chain shipping. Ground and other economy services are not available.
Purity
≥98%
Names and Identifiers
Canonical SmilesC1CNCCNCCCNCCNC1
IUPAC Name1,4,8,11-tetrazacyclotetradecane
InChIKeyMDAXKAUIABOHTD-UHFFFAOYSA-N
INCHI1S/C10H24N4/c1-3-11-7-9-13-5-2-6-14-10-8-12-4-1/h11-14H,1-10H2
Isomeric SMILES C1CNCCNCCCNCCNC1
WGK Germany 3
RTECS XA5254800
PubChem CID 64964
Molecular Weight 200.32
Beilstein 111811
Reaxy-Rn 111811

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganic nitrogen compounds
ClassOrganonitrogen compounds
SubclassAmines
Intermediate Tree Nodes Secondary amines
Direct ParentDialkylamines
Alternative Parents Azacyclic compounds  Organopnictogen compounds  Hydrocarbon derivatives  
Molecular FrameworkAliphatic heteromonocyclic compounds
Substituents Azacycle - Organoheterocyclic compound - Secondary aliphatic amine - Organopnictogen compound - Hydrocarbon derivative - Aliphatic heteromonocyclic compound
DescriptionThis compound belongs to the class of organic compounds known as dialkylamines. These are organic compounds containing a dialkylamine group, characterized by two alkyl groups bonded to the amino nitrogen.
External Descriptors azacycloalkane - saturated organic heteromonocyclic parent - crown amine
3D Structure
Interactive Chemical Structure Model





Associated Targets(Human)
CXCR4 Tclin C-X-C chemokine receptor type 4 (3338 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MT4 (17854 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
A549 (127892 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HCT-116 (91556 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HeLa (62764 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SMN1 Tchem Survival motor neuron protein (34246 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Associated Targets(non-human)
Plasmodium falciparum (966862 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Human immunodeficiency virus 1 (70413 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Human immunodeficiency virus 2 (5592 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

26 results found

Lot NumberCertificate TypeDateItem
C2625127Certificate of AnalysisSep 10, 2025 T130042
I2525766Certificate of AnalysisSep 10, 2025 T130042
I2525765Certificate of AnalysisSep 10, 2025 T130042
I2525764Certificate of AnalysisSep 10, 2025 T130042
I2518522Certificate of AnalysisSep 10, 2025 T130042
I2518520Certificate of AnalysisSep 10, 2025 T130042
E2620160Certificate of AnalysisSep 10, 2025 T130042
F2019084Certificate of AnalysisApr 03, 2024 T130042
E2516073Certificate of AnalysisMar 20, 2024 T130042
J2425877Certificate of AnalysisMar 20, 2024 T130042
J2425874Certificate of AnalysisMar 20, 2024 T130042
J2425870Certificate of AnalysisMar 20, 2024 T130042
J2425871Certificate of AnalysisMar 20, 2024 T130042
J2425872Certificate of AnalysisMar 20, 2024 T130042
J2425873Certificate of AnalysisMar 20, 2024 T130042
D2415332Certificate of AnalysisMar 16, 2024 T130042
D2416544Certificate of AnalysisMar 16, 2024 T130042
L1412065Certificate of AnalysisSep 17, 2022 T130042
J2318772Certificate of AnalysisAug 13, 2022 T130042
K2225714Certificate of AnalysisAug 13, 2022 T130042
K2225715Certificate of AnalysisAug 13, 2022 T130042
K2225728Certificate of AnalysisAug 13, 2022 T130042
K2225729Certificate of AnalysisAug 13, 2022 T130042
K2225730Certificate of AnalysisAug 13, 2022 T130042
A2419075Certificate of AnalysisAug 13, 2022 T130042
E1826005Certificate of AnalysisApr 11, 2022 T130042

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Chemical and Physical Properties
SolubilitySoluble in water. Solubility in Methanol very faint turbidity.
SensitivityMoisture sensitive
Melt Point(°C)185-188°C
Molecular Weight200.320 g/mol
XLogP3-1.600
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count4
Rotatable Bond Count0
Exact Mass200.2 Da
Monoisotopic Mass200.2 Da
Topological Polar Surface Area48.100 Ų
Heavy Atom Count14
Formal Charge0
Complexity92.700
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Documents & Articles
Citations of This Product
References
1. Luyao Liu, Chaowei Han, Meng Jiang, Tiantian Zhang, Qing Kang, Xiaoying Wang, Pengcheng Wang, Feimeng Zhou.  (2021)  Rapid and regenerable surface plasmon resonance determinations of biomarker concentration and biomolecular interaction based on tris-nitrilotriacetic acid chips.  ANALYTICA CHIMICA ACTA,      [PMID:34090589] [10.1016/j.aca.2021.338625]
2. Binbin Su, Chenning Sun, Jiahui Wei, Zhichao Chang, Yayun Zhou, Guojun Zhou, Huidong Xie, Zhiguo Xia.  (2026)  Solution-Processable Copper Iodide Scintillator for High-Resolution Planar-Curved X-Ray Imaging.  Advanced Optical Materials,  14  (13): (e71145).  [PMID:] [10.1002/adom.71145]
Solution Calculators
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