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| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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Moligand™,10mM in DMSO Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
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Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
AZD1940 is an orally active, high affinity cannabinoid CB1/CB2 receptor agonist with pK i values of 7.93 and 9.06 for human CB1R and CB2R , respectively. AZD1940 shows a robust analgesia action
In Vitro
AZD1940 binds with high affinity to human, rat and mouse CB1 and CB2 receptors and displays full agonism at both receptors in all three species . MCE has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
When given orally to rats, AZD1940 produces a robust analgesia in different models of inflammatory and neuropathic pain. For AZD1940, low brain uptake at analgesic doses has been demonstrated in both rats and primates . MCE has not independently confirmed the accuracy of these methods. They are for reference only.
IC50& Target:hCB1-R 7.93 (pKi) hCB2-R 9.06 (pKi)
| Isomeric SMILES | CCS(=O)(=O)NC1=CC2=C(C=C1)N(C(=N2)C(C)(C)C)CC3CCC(CC3)(F)F |
|---|---|
| Alternate CAS | 881413-29-2 |
| PubChem CID | 11675994 |
| MeSH Entry Terms | AZD1940;N-(2-tert-butyl-1-((4,4-difluorocyclohexyl)methyl)-1H-benzo(d)imidazol-5-yl)ethanesulfonamide |
| Molecular Weight | 413.52 |
Comprehensive hazard, handling, storage, and regulatory compliance document.
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