Dess-Martin Periodinane（DMP） - ≥96% , CAS No.87413-09-0

CAS: 87413-09-0 Cat. No.: D110230 Molecular Weight: 424.14 EC Number: 672-328-8

GRADE & PURITY ≥96%

Synonyms

DMP | 1,1,1-triacetoxy-1,1-dihydro-1,2-benziodoxyl-3(1H)-one | 1,2-Benziodoxol-3(1H)-one, 1,1,1-tris(acetyloxy)-1,1-dihydro- | ACETIC ACID, 1,1',1''-(3-OXO-1.LAMBDA.5-1,2-BENZIODOXOL-1(3H)-YLIDYNE) ESTER | AKOS005146141 | DessMartin periodinane | Dess-Mar

Storage

Protected from light,Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

Overview

Used for the oxidation of hydroxychlorins to chlorin-α-diones and tetraones.Dess-Martin periodinane (DMP) is a hypervalent iodine compound widely used as a mild reagent for the oxidation of primary/secondary alcohols to aldehydes/ketones; oxidation of amides into imides; the dehydrogenation of amines to nitriles, and disulfides to sulfones. It is also used to selectively oxidize alkenes to epoxides. This is a useful reaction for generating three-membered cyclic ethers. Additionally, DMP is used to oxidatively cleave 1,2-diols to form aldehydes or ketones and in the synthesis of lactones.

Application：

Dess–Martin periodinane is used as an oxidizing agent:
For 1° and 2° alcohols to aldehydes and ketones.
In the synthesis of N-protected α-amino aldehydes from the corresponding N-protected β-amino alcohols.
To synthesize alkynyl oxoaldehyde probe (AlkMGO).
Used for the oxidation of hydroxychlorins to chlorin-α-diones and tetraones.

Specifications

Synonyms

DMP | 1, 1, 1-triacetoxy-1, 1-dihydro-1, 2-benziodoxyl-3(1H)-one | 1, 2-Benziodoxol-3(1H)-one, 1, 1, 1-tris(acetyloxy)-1, 1-dihydro- | ACETIC ACID, 1, 1', 1''-(3-OXO-1.LAMBDA.5-1, 2-BENZIODOXOL-1(3H)-YLIDYNE) ESTER | AKOS005146141 | DessMartin periodinane | Dess-Mar

Specifications & Purity

≥96%

Storage

Protected from light, Store at -20°C, Argon charged

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥96%

Names and Identifiers

• Canonical Smiles: CC(=O)OI1(C2=CC=CC=C2C(=O)O1)(OC(=O)C)OC(=O)C
• IUPAC Name: (1,1-diacetyloxy-3-oxo-1λ5,2-benziodoxol-1-yl) acetate
• InChIKey: NKLCNNUWBJBICK-UHFFFAOYSA-N
• INCHI: 1S/C13H13IO8/c1-8(15)19-14(20-9(2)16,21-10(3)17)12-7-5-4-6-11(12)13(18)22-14/h4-7H,1-3H3
• Isomeric SMILES: CC(=O)OI1(C2=CC=CC=C2C(=O)O1)(OC(=O)C)OC(=O)C
• WGK Germany: 3
• UN Number: 1479
• Packing Group: II
• Molecular Weight: 424.14
• Reaxy-Rn: 4548207

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Class Carboxylic acids and derivatives
      • Subclass Tetracarboxylic acids and derivatives

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Class: Carboxylic acids and derivatives
• Subclass: Tetracarboxylic acids and derivatives
• Intermediate Tree Nodes: Not available
• Direct Parent: Tetracarboxylic acids and derivatives
• Alternative Parents: Benzenoids Aryl iodides Acetate salts Oxacyclic compounds Organic salts Organic oxides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Tetracarboxylic acid or derivatives - Benzenoid - Aryl iodide - Aryl halide - Acetate salt - Carboxylic acid salt - Oxacycle - Organoheterocyclic compound - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Organic salt - Organooxygen compound - Carbonyl group - Aromatic heteropolycyclic compound
• Description: This compound belongs to the class of organic compounds known as tetracarboxylic acids and derivatives. These are carboxylic acids containing exactly four carboxyl groups.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Associated Targets(non-human)

Ptpn1 Protein-tyrosine phosphatase 1B (270 Activities)

Discover Target: Ptpn1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Chemical and Physical Properties

• Solubility: Soluble in chloroform, acetone, acetonitrile and methylene chloride. Slightly soluble in ether and hexane.
• Sensitivity: Light & Moisture & heat & Air Sensitive
• Melt Point(°C): 130-133°C
• Molecular Weight: 424.140 g/mol
• XLogP3: 2.700
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 8
• Rotatable Bond Count: 6
• Exact Mass: 423.966 Da
• Monoisotopic Mass: 423.966 Da
• Topological Polar Surface Area: 105.000 Ų
• Heavy Atom Count: 22
• Formal Charge: 0
• Complexity: 499.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

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