GRADE & PURITYValidated?Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated.1.0 mg/mL
Validated, 1.0 mg/mL Validated for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping
Store at -20°C,Avoid repeated freezing and thawing Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
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Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Overview
Rabbit anti Human RAP1 Antibody, Polyclonal, could be used for WB, IHC and so on. Application: WB: 1/500-1/2000 IHC: 1/50-1/300 Protein Function Acts both as a regulator of telomere function and as a transcription regulator. Involved in the regulation of telomere length and protection as a component of the shelterin complex (telosome). In contrast to other components of the shelterin complex, it is dispensible for telomere capping and does not participate in the protection of telomeres against non-homologous end-joining (NHEJ)-mediated repair. Instead, it is required to negatively regulate telomere recombination and is essential for repressing homology-directed repair (HDR), which can affect telomere length. Does not bind DNA directly: recruited to telomeric double-stranded 5'-TTAGGG-3' repeats via its interaction with TERF2. Independently of its function in telomeres, also acts as a transcription regulator: recruited to extratelomeric 5'-TTAGGG-3' sites via its association with TERF2 or other factors, and regulates gene expression. When cytoplasmic, associates with the I-kappa-B-kinase (IKK) complex and acts as a regulator of the NF-kappa-B signaling by promoting IKK-mediated phosphorylation of RELA/p65, leading to activate expression of NF-kappa-B target genes.
Specifications
Product Name
RAP1 Antibody - Primary antibody, specific to TERF2IP, Rabbit IgG
A synthetic peptide derived from human RAP1 (AA 203-252)
Positive Control
WB: HEK293 and Hep G2 cell lysates. IHC: human Gastric adenocarcinoma tissue.
Conjugation
Unconjugated
Grade
Validated
Isotype
Rabbit IgG
SDS-PAGE
150 kDa
Purification Method
Immunogen affinity purified
Concentration
1.0 mg/mL
Storage and Shipping
Shape
Liquid
Storage
Store at -20°C,Avoid repeated freezing and thawing
Shipped In
Ice chest + Ice pads
Stability And Storage
Store at -20°C long term (12 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
Images
RAP1 Antibody (Ab124571) - Western Blot All lanes: RAP1 Antibody (Ab124571) at 1/1000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution Predicted band size: 44 kDa Observed band size: 57 kDa Exposure time: 120.0 s
RAP1 Antibody (Ab124571) - IHC Immunohistochemical analysis of paraffin-embedded human Gastric adenocarcinoma. 1. RAP1 Antibody (Ab124571) was diluted at 1/200 (4℃, overnight) 2. Tris-EDTA, pH 9.0 was used for antigen retrieval 3. Secondary antibody was diluted at 1/200 (room temperature, 45 min).
Application
Application
Dilution info
WB
1/500-1/2000
IHC
1/50-1/300
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
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