GRADE & PURITYCarrier Free?Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays.His Tag?His tag grade — recombinant protein bearing a His tag for affinity purification/detection. Use to purify, immobilize, or detect the tagged protein.≥90%(SDS-PAGE)
Carrier Free,His-Tag,≥90%(SDS-PAGE) Carrier Free,His Tag for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping
Store at -20°C,Avoid repeated freezing and thawing Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
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Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Overview
SOX2 is a member of the SOXB1 subfamily of transcription factors most notably involved in the reprogramming of somatic cells into induced pluripotent stem cells. Housed on chromosome 3, the SOX2 gene encodes for a protein with a C-terminal transcriptional activation domain and a DNA-binding HMG domain that contains a nuclear localization/export signal. SOX2 forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development and pluripotency such as YES1, FGF4, UTF1 and ZFP206. Mutations in this gene have been associated with bilateral eye disease. SOX2 antigen and antibody were found in small-cell lung cancer cell lines and sera. However, neither exists in normal sera, suggesting that SOX2 might be a potential tumor target or marker.
Specifications
Product Name
Recombinant Human SOX2 Protein
Synonyms
cb236 | Delta EF2a | Lcc | MCOPS3 | MGC148683 | MGC2413 | RGD1565646 | Sex determining region Y box 2 | ANOP3 | SOX 2 | Sox2 | SOX2_HUMAN | SRY (sex determining region Y) box 2 | SRY box containing gene 2 | SRY related HMG box 2 | SRY related HMG box gene
37.3 kDa, under reducing conditions; 37.3 kDa, under non-reducing conditions
Molecule Type
Protein
Storage and Shipping
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute at 1.0 mg/mL in sterile distilled water. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
Storage
Store at -20°C,Avoid repeated freezing and thawing
Shipped In
Ice chest + Ice pads
Stability And Storage
Store at -20°C for 1 year. Avoid freeze / thaw cycle.
Images
Recombinant Human SOX2 Protein (rp156646) - SDS-PAGE 3 μg/lane of Recombinant Human SOX2 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 37.3 kDa.
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
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