4-[4-(Dimethylamino)phenylazo]benzoic acid N-succinimidyl ester - ≥97% , CAS No.146998-31-4

CAS: 146998-31-4 Cat. No.: D131109 Molecular Weight: 366.371

GRADE & PURITY ≥97%

Synonyms

SCHEMBL608694 | 4-((4-(Dimethylamino)phenyl)azo)benzoic acid N-succinimidyl ester | DABCYL N-Succinimidyl Ester | S0857 | FT-0733519 | 4-[4-(Dimethylamino)phenylazo]benzoic acid N-succinimidyl ester? | F12219 | 4-((4-(Dimethylamino)phenyl)azo)benzoicacid

Storage

Protected from light,Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

Overview

Non-Fluorescent probe for labeling proteins or peptides

Specifications

Synonyms

SCHEMBL608694 | 4-((4-(Dimethylamino)phenyl)azo)benzoic acid N-succinimidyl ester | DABCYL N-Succinimidyl Ester | S0857 | FT-0733519 | 4-[4-(Dimethylamino)phenylazo]benzoic acid N-succinimidyl ester? | F12219 | 4-((4-(Dimethylamino)phenyl)azo)benzoicacid

Specifications & Purity

≥97%

Biochemical and Physiological Mechanisms

Long wavelength azo quencher - useful as a reagent to label proteins or peptides through their amino-groups. The succinimidyl ester is reactive with terminal amines or lysines of peptides and other nucleophiles.

Storage

Protected from light, Store at -20°C, Argon charged

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Note

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Refer to SDS for further information. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Purity

≥97%

Names and Identifiers

• Canonical Smiles: CN(C)C1=CC=C(C=C1)N=NC2=CC=C(C=C2)C(=O)ON3C(=O)CCC3=O
• IUPAC Name: (2,5-dioxopyrrolidin-1-yl) 4-[[4-(dimethylamino)phenyl]diazenyl]benzoate
• InChIKey: IBOVDNBDQHYNJI-UHFFFAOYSA-N
• INCHI: 1S/C19H18N4O4/c1-22(2)16-9-7-15(8-10-16)21-20-14-5-3-13(4-6-14)19(26)27-23-17(24)11-12-18(23)25/h3-10H,11-12H2,1-2H3
• Isomeric SMILES: CN(C)C1=CC=C(C=C1)N=NC2=CC=C(C=C2)C(=O)ON3C(=O)CCC3=O
• Molecular Weight: 366.371
• Reaxy-Rn: 8574706
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=8574706&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Class Azobenzenes

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Class: Azobenzenes
• Subclass: Not available
• Intermediate Tree Nodes: Not available
• Direct Parent: Azobenzenes
• Alternative Parents: Benzoic acids and derivatives Aniline and substituted anilines Benzoyl derivatives Dialkylarylamines Pyrrolidine-2-ones Dicarboximides Lactams Amino acids and derivatives Carboxylic acid salts Azo compounds Azacyclic compounds Propargyl-type 1,3-dipolar organic compounds Monocarboxylic acids and derivatives Hydrocarbon derivatives Organic oxides Carbonyl compounds Organic salts Organopnictogen compounds
• Molecular Framework: Aromatic heteromonocyclic compounds
• Substituents: Azobenzene - Benzoic acid or derivatives - Tertiary aliphatic/aromatic amine - Dialkylarylamine - Aniline or substituted anilines - Benzoyl - Pyrrolidone - 2-pyrrolidone - Benzenoid - Monocyclic benzene moiety - Dicarboximide - Pyrrolidine - Lactam - Amino acid or derivatives - Carboxylic acid salt - Tertiary amine - Azo compound - Carboxylic acid derivative - Azacycle - Organic 1,3-dipolar compound - Monocarboxylic acid or derivatives - Propargyl-type 1,3-dipolar organic compound - Organic salt - Organic nitrogen compound - Amine - Carbonyl group - Hydrocarbon derivative - Organic oxide - Organic oxygen compound - Organonitrogen compound - Organooxygen compound - Organopnictogen compound - Aromatic heteromonocyclic compound
• Description: This compound belongs to the class of organic compounds known as azobenzenes. These are organonitrogen aromatic compounds that contain a central azo group, where each nitrogen atom is conjugated to a benzene ring.
• External Descriptors: pyrrolidinone - monoazo compound

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Solubility: Soluble in DMSO.
• Sensitivity: Light Sensitive,Moisture Sensitive,Heat Sensitive
• Melt Point(°C): 242 °C(dec.)
• Molecular Weight: 366.400 g/mol
• XLogP3: 2.800
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 6
• Exact Mass: 366.133 Da
• Monoisotopic Mass: 366.133 Da
• Topological Polar Surface Area: 91.600 Ų
• Heavy Atom Count: 27
• Formal Charge: 0
• Complexity: 575.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1