GRADE & PURITYCarrier Free?Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays.Validated?Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated.Azide Free?Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory.PBS Only?PBS-only formulation — supplied in phosphate-buffered saline with no other additives. Use when you need a clean PBS buffer free of stabilizers/carriers.≥95%(SDS-PAGE)See COA
Carrier Free, Azide Free, Validated, PBS Only, ≥95%(SDS-PAGE), See COA Azide Free,Carrier Free,PBS Only,Validated for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping
Store at 2-8°C,Do not freeze Ships Wet ice,Do not freeze Check lot-specific COA for exact specifications.
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Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Overview
Armenian Hamster anti Mouse DR5/CD262 Antibody, Monoclonal (MD5-1), could be used for Flow, in vitro induction TRAIL-mediated apoptosis, in vivo induction TRAIL-mediated apoptosis and so on. Application: Flow: Use at an assay dependent concentration. in vitro induction TRAIL-mediated apoptosis: Use at an assay dependent concentration. in vivo induction TRAIL-mediated apoptosis: Use at an assay dependent concentration. Protein Function Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B. Essential for ER stress-induced apoptosis.
Specifications
Product Name
DR5/CD262 Armenian Hamster mAb - Primary antibody, specific to DR5/CD262, Armenian Hamster IgG
Synonyms
MK | Ly98 | KILLER | TRICK2B | CD262 antigen | CD262 | death domain containing receptor for TRAIL/Apo-2L | Death receptor 5 | DR5 | DR5TRICK2B | Fas-like protein | KILLER/DR5 | KILLERapoptosis inducing protein TRICK2A/2B | TNF-related apoptosis-inducing l
Specifications & Purity
Carrier Free, Azide Free, Validated, PBS Only, ≥95%(SDS-PAGE), See COA
Host species
Armenian hamster
Specificity
DR5/CD262
Immunogen
Mouse DR5-Ig fusion protein
Conjugation
Unconjugated
Grade
Azide Free, Carrier Free, PBS Only, Validated
Isotype
Armenian Hamster IgG
Light Chain Type
kappa
SDS-PAGE
150 kDa
Purification Method
Protein G purified
Concentration
See COA
Storage and Shipping
Shape
Liquid
Storage
Store at 2-8°C,Do not freeze
Shipped In
Wet ice,Do not freeze
Stability And Storage
Shipped at 4°C. Store at 4°C long term (12 months). Do not freeze. Upon receipt, it is recommended to aliquot.
Images
DR5/CD262 Armenian Hamster mAb (Ab100457) - Flow Cytometry Flow Cytometry analysis of 2.5 μg/mL Con A stimulated mouse splenocytes cells (72h) labelling DR5/CD262 with DR5/CD262 Armenian Hamster mAb (Ab100457) conjugated with biotin (right panel) at 5.0 μg/mL for 1 hour at 4°C, compared with Armenian Hamster IgG Isotype Control Antibody (Biotin) (Ab135991) (left panel) and detected with SA-PE (rp156150).
DR5/CD262 Armenian Hamster mAb (Ab100457) - Flow Cytometry Flow Cytometry analysis of 2.5 μg/mL Con A stimulated mouse splenocytes cells (72h) labelling DR5/CD262 (red) with DR5/CD262 Armenian Hamster mAb (Ab100457) conjugated with biotin at 5.0 μg/mL for 1 hour at 4°C, and detected with SA-PE (rp156150). Blue - Armenian Hamster IgG Isotype Control Antibody (Biotin) (Ab135991). Black - Unlabelled control, cells without incubation with primary antibody.
Application
Application
Dilution info
Flow Cytometry
Use at an assay dependent concentration.
in vitro induction TRAIL-mediated apoptosis
Use at an assay dependent concentration.
in vivo induction TRAIL-mediated apoptosis
Use at an assay dependent concentration.
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
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