MW 3400 Da for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -20°C,Argon charged Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 2 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
DSPE PEG Maleimide is one of Nanocs reactive phospholipid PEG reagents that can react with sulfhydryl (thiol, -SH) groups. DSPE (1,2-Distearoyl-sn-Glycero-3-Phosphoethanolamine) is a saturated 18C phospholipid that is highly hydrophobic. PEG linker (polyethylene glycol), on the other hand, offers good hydrophilicity and water solubility. Maleimide functional DSPE PEG has excellent reactivity towards sulfhydryl/thiol groups derived from various molecules.
Application
Reaction between maleimide and thiolproceeds easily at neutral pH. Maleimide PEG DSPE is one of most commonly used reactive phospholipids to conjugate antibodies, peptides or other ligands to the surface of liposome and other lipid PEG nanoparticles. Pegylated phospholipids have longer blood circulation time and higher stability for encapsulated drugs.
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →| Solubility | Soluble in chloroform and warm water |
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| 1. Xiaozhuo Ba, Tao Ye, Yu He, Yonghua Tong, Haojie Shang, Jian Wu, Wen Deng, Zichen Zhong, Xiaoqi Yang, Kangyang Wang, Yabin Xie, Kehua Jiang, Xiaolin Guo, Kun Tang. (2025) Engineered macrophage membrane-coated nanoparticles attenuate calcium oxalate nephrocalcinosis-induced kidney injury by reducing oxidative stress and pyroptosis. Acta Biomaterialia, [PMID:39947306] [10.1016/j.actbio.2025.02.021] |
| 2. Jian Cui, Zhiwei Wen, Huajie Huang, Shuilin Qin, Yanjie Luo, Wei Zhang, Wei Wu. (2024) The Pharmacokinetics and Liver-Targeting Evaluation of Silybin Liposomes Mediated by the NTCP/OCTN2 Dual Receptors. MOLECULAR PHARMACEUTICS, [PMID:39370820] [10.1021/acs.molpharmaceut.3c01245] |
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