Ganitumab (anti-IGF1R) - Primary antibody, specific to IGF1R, >95%, Human IgG1, ANTAGONIST of Insulin-like growth factor I receptor antagonist, ANTAGONIST of Insulin-like growth factor I receptor antagonist

CAS: 905703-97-1 Cat. No.: Ab177931
AVAILABLE TO ORDER
GRADE & PURITY Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. ≥95%(SDS-PAGE&SEC-HPLC) See COA
Application
Animal Model, ELISA, Flow Cytometry, Functional Assay
Host species
Human
Reactive species
Human
Isotype
Human IgG1
Conjugation
Unconjugated
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
100μg
Ab177931-100μg
10
$92.90
1mg
Ab177931-1mg
4
$575.90
5mg
Ab177931-5mg
1
$1,509.90
10mg
Ab177931-10mg
1-2 wks(?)
Item is derived from our semi-finished stock and is processed in 1-2 weeks.
$2,419.90
Enter a quantity for the sizes you want to add.
🧪

Why this grade

Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA Animal Free,Azide Free,Carrier Free,ExactAb™,Low Endotoxin,Recombinant,Validated for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -80°C,Avoid repeated freezing and thawing Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

Ganitumab (anti-IGF1R) is a recombinant human monoclonal antibody to the human type 1 insulin-like growth factor receptor (IGF1R).Ganitumab (anti-IGF1R) recognizes murine IGF1R with sub-nanomolar affinity (KD=0.22 nM) and inhibits the interaction of murine IGF1R with IGF1 and IGF2.Ganitumab (anti-IGF1R) can be used in research of cancer.

Specifications

Product Name
Ganitumab (anti-IGF1R) - Primary antibody, specific to IGF1R, >95%, Human IgG1, ANTAGONIST of Insulin-like growth factor I receptor antagonist
Synonyms
EC 2.7.10.1 | IGF-I receptor | Insulin-like growth factor I receptor
Specifications & Purity
Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species
Human
Specificity
IGF1R
Conjugation
Unconjugated
Grade
Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Action Type
ANTAGONIST
Mechanism of action
ANTAGONIST of Insulin-like growth factor I receptor antagonist
Isotype
Human IgG1
Light Chain Type
kappa
SDS-PAGE
26.8 kDa (Light Chain) & 50.4 kDa (Heavy Chain), under reducing conditions; 200.6 kDa, under non-reducing conditions.
Purification Method
Protein A purified
Purity
>95%
Concentration
See COA
CAS
905703-97-1
Storage and Shipping
Shape
Liquid
Storage
Store at -80°C,Avoid repeated freezing and thawing
Shipped In
Dry ice packs + Cold packs
Stability And Storage
Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
Images

Ganitumab (anti-IGF1R) (Ab177931) - Flow Cytometry
Flow Cytometry analysis of MCF-7 cells labelling IGF1R (red) with Ganitumab (anti-IGF1R) (Ab177931). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

Ganitumab (anti-IGF1R) (Ab177931) - SEC
The purity of Ganitumab (anti-IGF1R) (Ab177931) is more than 95% verified by HPLC.

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Associated Targets(Human)
IGF1R Tclin Insulin-like growth factor 1 receptor (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
IGF1R Tclin Insulin-like growth factor I receptor (8605 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot NumberCertificate TypeDateItem
ZJ24F0606938Certificate of AnalysisApr 16, 2026 Ab177931
ZJ24F0606939Certificate of AnalysisApr 16, 2026 Ab177931
ZJ24F0606940Certificate of AnalysisApr 16, 2026 Ab177931
Solution Calculators
Reviews

Customer Reviews

Need help choosing the grade?

Our grade selection guide covers purity, stabilizer status, and application suitability for all variants in our catalog.

View Animal Free grade guide → View Carrier Free grade guide → View Recombinant grade guide → View Validated grade guide → View ExactAb™ grade guide → View Low Endotoxin grade guide → View Azide Free grade guide →

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