FAP

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  1. SP-13786
    CAS: 1448440-52-5 PubChem CID: 71621488 Summenformel: C17H14F2N4O2 Molekulargewicht: 344.32
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥97%
    ● Auf Lager — US-Lager, Versand in die EU* Artikel #: S174266
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    N-[2-[(2S)-2-cyano-4,4-difluoropyrrolidin-1-yl]-2-oxoethyl]quinoline-4-carboxamide
    SMILES
    C1C(N(CC1(F)F)C(=O)CNC(=O)C2=CC=NC3=CC=CC=C23)C#N
    InChIKey
    PUOOCZVRHBHJRS-NSHDSACASA-N
    InChI
    1S/C17H14F2N4O2/c18-17(19)7-11(8-20)23(10-17)15(24)9-22-16(25)13-5-6-21-14-4-2-1-3-12(13)14/h1-6,11H,7,9-10H2,(H,22,25)/t11-/m0/s1
    Synonyme
    AKOS027423971 | EX-A2803 | N-[2-[(2S)-2-Cyano-4,4-difluoro-1-pyrrolidinyl]-2-oxoethyl]-4-quinolinecarboxamide | ZB149...
  2. WAY-323975
    CAS: 510716-65-1 PubChem CID: 1073012 Summenformel: C16H22ClN3O5S Molekulargewicht: 403.88
    10mM in DMSO
    ● Auf Lager — US-Lager, Versand in die EU* Artikel #: W424395
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    ethyl 4-[2-[(4-chlorophenyl)sulfonyl-methylamino]acetyl]piperazine-1-carboxylate
    SMILES
    CCOC(=O)N1CCN(CC1)C(=O)CN(C)S(=O)(=O)C2=CC=C(C=C2)Cl
    InChIKey
    GVRRKYYMISVYGI-UHFFFAOYSA-N
    InChI
    1S/C16H22ClN3O5S/c1-3-25-16(22)20-10-8-19(9-11-20)15(21)12-18(2)26(23,24)14-6-4-13(17)5-7-14/h4-7H,3,8-12H2,1-2H3
  3. WAY-323975
    CAS: 510716-65-1 PubChem CID: 1073012 Summenformel: C16H22ClN3O5S Molekulargewicht: 403.88
    ● Auf Lager — US-Lager, Versand in die EU* Artikel #: W416981
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    IUPAC-Bezeichnung
    ethyl 4-[2-[(4-chlorophenyl)sulfonyl-methylamino]acetyl]piperazine-1-carboxylate
    SMILES
    CCOC(=O)N1CCN(CC1)C(=O)CN(C)S(=O)(=O)C2=CC=C(C=C2)Cl
    InChIKey
    GVRRKYYMISVYGI-UHFFFAOYSA-N
    InChI
    1S/C16H22ClN3O5S/c1-3-25-16(22)20-10-8-19(9-11-20)15(21)12-18(2)26(23,24)14-6-4-13(17)5-7-14/h4-7H,3,8-12H2,1-2H3
  4. FAPI-34
    CAS: 2374782-07-5 Summenformel: C50H57F2N13O18 Molekulargewicht: 1166.06
    ◐ .Auf Bestellung · 8–12 Wochen Artikel #: F647693
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    SMILES
    O=C(C1=CC=NC(C=C2)=C1C=C2OCCCN(CC3)CCN3C(CN(CC4=NC=CN4CC(N[C@H](C(O)=O)CC(C(O)=O)C(O)=O)=O)CC5=NC=CN5CC(N[C@H](C(O)=O)CC(C(O)=O)C(O)=O)=O)=O)NCC(N(CC6show more
  5. FAPI-4 TFA salt
    CAS: 2374782-02-0(free base) Summenformel: C40H54F2N10O10(free base) Molekulargewicht: 872.91(free base)
    Feststoff Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ◐ .Auf Bestellung · 8–12 Wochen Artikel #: F648286
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    2-[4,7-bis(carboxymethyl)-10-[2-[4-[3-[4-[[2-[(2S)-2-cyano-4,4-difluoropyrrolidin-1-yl]-2-oxoethyl]carbamoyl]quinolin-6-yl]oxypropyl]piperazin-1-yl]-2show more
    SMILES
    C1CN(CCN1CCCOC2=CC3=C(C=CN=C3C=C2)C(=O)NCC(=O)N4CC(CC4C#N)(F)F)C(=O)CN5CCN(CCN(CCN(CC5)CC(=O)O)CC(=O)O)CC(=O)O
    InChIKey
    ICWDAESAANBIGG-LJAQVGFWSA-N
    InChI
    1S/C40H54F2N10O10/c41-40(42)21-29(22-43)52(28-40)34(53)23-45-39(61)31-4-5-44-33-3-2-30(20-32(31)33)62-19-1-6-46-15-17-51(18-16-46)35(54)24-47-7-9-48(2show more
    Synonyme
    MS-31619 | FAPI-04 | FAPI-4 | ICWDAESAANBIGG-LJAQVGFWSA-N | AT39479 | DOTA-fapi-04 | EX-A5967 | 2-[4,7-bis(carboxymet...
  6. Suc-Gly-Pro-AMC
    CAS: 80049-85-0 PubChem CID: 21121742 Summenformel: C21H23N3O7 Molekulargewicht: 429.42
    ◐ .Auf Bestellung · 8–12 Wochen Artikel #: S648136
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    4-[[2-[(2S)-2-[(4-methyl-2-oxochromen-7-yl)carbamoyl]pyrrolidin-1-yl]-2-oxoethyl]amino]-4-oxobutanoic acid
    SMILES
    CC1=CC(=O)OC2=C1C=CC(=C2)NC(=O)C3CCCN3C(=O)CNC(=O)CCC(=O)O
    InChIKey
    NKEPCOOQNLGSLJ-HNNXBMFYSA-N
    InChI
    1S/C21H23N3O7/c1-12-9-20(29)31-16-10-13(4-5-14(12)16)23-21(30)15-3-2-8-24(15)18(26)11-22-17(25)6-7-19(27)28/h4-5,9-10,15H,2-3,6-8,11H2,1H3,(H,22,25)(Hshow more
    Synonyme
    4-[[2-[(2S)-2-[(4-methyl-2-oxochromen-7-yl)carbamoyl]pyrrolidin-1-yl]-2-oxoethyl]amino]-4-oxobutanoic acid | HY-14598...
  7. Ac-Gly-BoroPro
    CAS: 886992-99-0 PubChem CID: 102176419 Summenformel: C8H15BN2O4 Molekulargewicht: 214.03
    ◐ .Auf Bestellung · 8–12 Wochen Artikel #: A650587
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    [(2S)-1-(2-acetamidoacetyl)pyrrolidin-2-yl]boronic acid
    SMILES
    B(C1CCCN1C(=O)CNC(=O)C)(O)O
    InChIKey
    UUOZISWTWURDGU-SSDOTTSWSA-N
    InChI
    1S/C8H15BN2O4/c1-6(12)10-5-8(13)11-4-2-3-7(11)9(14)15/h7,14-15H,2-5H2,1H3,(H,10,12)/t7-/m1/s1
  8. OncoFAP
    CAS: 2639365-69-6 Summenformel: C21H19F2N5O5 Molekulargewicht: 459.40
    ◐ .Auf Bestellung · 8–12 Wochen Artikel #: O651308
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    SMILES
    OC(CCC(NC1=CC=CC2=C1N=CC=C2C(NCC(N3[C@@H](CC(F)(C3)F)C#N)=O)=O)=O)=O
  9. FAP-2286
    CAS: 2581741-18-4 Summenformel: C67H99N13O18S3 Molekulargewicht: 1470.77
    ◐ .Auf Bestellung · 8–12 Wochen Artikel #: F646366
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    SMILES
    O=C(N1[C@@](C(N[C@@](C(N[C@H](C(N[C@H](C2=O)CC3=CC=CC=C3)=O)CCC(N)=O)=O)([H])[C@H](O)C)=O)([H])CCC1)[C@@](CCC4)([H])N4C([C@H](CSCC5=CC(CSCCNC(CN(CCN(Cshow more
  10. FAPI-46
    CAS: 2374782-04-2 PubChem CID: 139400499 Summenformel: C41H57F2N11O9 Molekulargewicht: 885.96
    ◐ .Auf Bestellung · 8–12 Wochen Artikel #: F650690
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    IUPAC-Bezeichnung
    2-[4,7-bis(carboxymethyl)-10-[2-[4-[3-[[4-[[2-[(2S)-2-cyano-4,4-difluoropyrrolidin-1-yl]-2-oxoethyl]carbamoyl]quinolin-6-yl]-methylamino]propyl]piperashow more
    SMILES
    CN(CCCN1CCN(CC1)C(=O)CN2CCN(CCN(CCN(CC2)CC(=O)O)CC(=O)O)CC(=O)O)C3=CC4=C(C=CN=C4C=C3)C(=O)NCC(=O)N5CC(CC5C#N)(F)F
    InChIKey
    SDBGUEFOSXNKBX-HKBQPEDESA-N
    InChI
    1S/C41H57F2N11O9/c1-47(30-3-4-34-33(21-30)32(5-6-45-34)40(63)46-24-35(55)54-29-41(42,43)22-31(54)23-44)7-2-8-48-17-19-53(20-18-48)36(56)25-49-9-11-50(show more
    Synonyme
    2374782-04-2 | 59QC5DY68A | AKOS040757603 | FAPI-46 | SCHEMBL21257093 | MS-31645 | EX-A5968 | [10-[2-[4-[3-[[4-[[[2-[...
  11. Sibrotuzumab (anti-FAP), BINDING AGENT of Fibroblast activation protein alpha binding agent
    CAS: 216669-97-5
    Flüssigkeit Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ≥95%(SDS-PAGE&SEC-HPLC) See COA
    ● Auf Lager — US-Lager, Versand in die EU* Artikel #: Ab183093
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    Associated targets
    FAP
    Short Overview
    Purity≥95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
    Reaktive Spezies
    Mensch
    Isotyp
    Human IgG1
    Wirtsspezies
    Mensch
    Konjugation
    Unconjugated
    SMILES
    [Sibrotuzumab]
    Synonyme
    170 kDa melanoma membrane-bound gelatinase antibody | Dipeptidyl peptidase FAP antibody | DPPIV antibody | FAP antibo...
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Häufig gestellte Fragen

How is the FAP listing put together?
It draws on reported FAP annotations within Immunology/Inflammation and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.
How do I choose a FAP modulator for my assay?
Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the FAP entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.
Which specifications matter most for FAP compounds?
Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For FAP work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What if the FAP compound I need is not listed?
Search by CAS number or SMILES first, since analogs of FAP compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.

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