Muromonab (anti-CD3) - Primärer Antikörper, for ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) various applications, specific to CD3, >95%, Mouse IgG2a

CAS: 140608-64-6 Cat. No.: Ab170491
Zu bestellen verfügbar
GRADE & PURITY Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. ≥95%(SDS-PAGE&SEC-HPLC) See COA
Application
Animal Model, ELISA, Flow Cytometry, Functional Assay
Host species
Maus
Reactive species
Mensch
Isotype
Mouse IgG2a
Conjugation
Unconjugated
★
Size
Deutschland (EU)
USA*
Price
Qty
100μg
Ab170491-100μg
Auf Bestellung · 8–12 Wochen
117,93€
1mg
Ab170491-1mg
—
1 Auf Lager
589,98€
5mg
Ab170491-5mg
Auf Bestellung · 8–12 Wochen
1.475,07€
10mg
Ab170491-10mg
Auf Bestellung · 8–12 Wochen
2.377,52€
Enter a quantity for the sizes you want to add.
🧪
Why this grade

Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA Animal Free,Azide Free,Carrier Free,ExactAb™,Low Endotoxin,Recombinant,Validated for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -80°C,Avoid repeated freezing and thawing Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Übersicht

Muromonab (anti-CD3) is a mouse monoclonal antibody targeting the CD3 antigen. Muromonab (anti-CD3) specifically binds to the CD3 antigen on the surface of human and higher primate T cells. Muromonab (anti-CD3) blocks the function of T cell receptors to recognize foreign antigens and inhibits T cell-mediated immune responses, including cell-mediated lymphocyte lysis and T cell proliferation responses. Muromonab (anti-CD3) can be used to study acute kidney, liver, heart and combined kidney-pancreas transplant rejection, and can also be used to study graft-versus-host disease in bone marrow transplant patients.

Specifications

Product Name
Muromonab (anti-CD3) - Primärer Antikörper, for ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) various applications, specific to CD3, >95%, Mouse IgG2a
Synonyme
CD_antigen: CD3e | CD3 antigen, delta subunit | CD3 | CD3d antigen | CD3d antigen, delta polypeptide (TiT3 complex) | CD3d molecule, delta (CD3-TCR complex) | CD3-DELTA | CD3e antigen | CD3e antigen, epsilon polypeptide (TiT3 complex) | CD3e molecule, eps
Spezifikationen & Reinheit
Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Biochemische und physiologische Mechanismen
The CD3 complex mediates signal transduction.
Wirtsspezies
Maus
Spezifität
CD3
Anmeldung
ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR)
Konjugation
Unconjugated
Note
Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Antikörper Typ
Primary antibody
Klonalität
Recombinant
Isotyp
Mouse IgG2a
Lichterketten-Typ
kappa
SDS-PAGE
146.34 kDa
Verfahren zur Reinigung
Protein A purified
Reinheit
>95%
Quelle
CHO supernatant
Konzentration
See COA
CAS
140608-64-6
Lagerung und Versand
Form
Liquid
Storage
Store at -80°C,Avoid repeated freezing and thawing
Verschickt in
Dry ice packs + Cold packs
Stabilität und Lagerung
Store at -80℃ long term (24 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
Bilder

Muromonab (anti-CD3) (Ab170491) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling CD3 with Muromonab (anti-CD3) (Ab170491) (right panel) conjugated with biotin compared with Human IgG (Ab170213) conjugated with biotin - Isotype Control (left panel) and detected with SA-PE (rp156150).

Muromonab (anti-CD3) (Ab170491) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling CD3 (red) with Muromonab (anti-CD3) (Ab170491) conjugated with biotin and detected with SA-PE (rp156150). Blue - Isotype control, human IgG (Ab170213) conjugated with biotin. Black - Unlabelled control, cells without incubation with primary antibody.

Muromonab (anti-CD3) (Ab170491) - Flow Cytometry
Flow Cytometry analysis of Jurkat cells labelling CD3 (red) with Muromonab (anti-CD3) (Ab170491). Goat Anti-Human IgG (FITC) (Ab175834) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

Muromonab (anti-CD3) (Ab170491) - SEC
The purity of Muromonab (anti-CD3) (Ab170491) is more than 95% verified by HPLC.

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Zugehörige Ziele (menschlich)
CD3E Tclin T-cell surface glycoprotein CD3 epsilon chain (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CD3E Tclin T-cell surface glycoprotein CD3 epsilon chain (0 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Wirkungsmechanismen
Zertifikate (CoA, COO, BSE/TSE und Analyse-Diagramm)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

5 results found

Lot NumberCertificate TypeDatumArtikel
ZJ24F0708072Certificate of AnalysisMay 19, 2026 Ab170491
ZJ23F1001371Certificate of AnalysisAug 12, 2025 Ab170491
ZJ23F1001372Certificate of AnalysisAug 12, 2025 Ab170491
ZJ26F0636103Certificate of AnalysisAug 12, 2025 Ab170491
ZJ26F0737975Certificate of AnalysisAug 12, 2025 Ab170491
FAQs und Artikel
Lösungsrechner
Bewertungen

Kundenbewertungen

Häufig gestellte Fragen

What does Animal Free mean?
Animal Free indicates that the material has been processed and tested for specialty industrial processing. Specifications focus on the impurities that affect performance in that application — for example, metal content for electronics, particle size for batteries, refractive index for optics, or moisture content for moisture-sensitive processes.
What does Carrier Free mean?
Carrier Free indicates that the material has been processed and tested for specialty industrial processing. Specifications focus on the impurities that affect performance in that application — for example, metal content for electronics, particle size for batteries, refractive index for optics, or moisture content for moisture-sensitive processes.
How should this product be stored?
Store at ?80 °C. Avoid repeated freeze–thaw cycles. Aliquot into single-use volumes before freezing.
How is this product shipped?
This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.
What are the CAS number, molecular formula and molecular weight?
The CAS Number is 140608-64-6.
What documentation is provided?
Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.
Which species reactivity has this antibody been validated against?
Validated reactivity is listed on the PDP and on each lot's datasheet. We validate against the most commonly tested species for the target (Muromonab (anti-CD3)); cross-reactivity in untested species may exist but is not guaranteed. Contact technical support for specific species inquiries.

Need help choosing the grade?

Our grade selection guide covers purity, stabilizer status, and application suitability for all variants in our catalog.

View Animal Free grade guide → View Carrier Free grade guide → View Recombinant grade guide → View Validated grade guide → View ExactAb™ grade guide → View Low Endotoxin grade guide → View Azide Free grade guide →

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