(R)-(+)-α,α-Diphenyl-2-pyrrolidinemethanol trimethylsilyl ether - ≥96% , CAS No.943757-71-9

CAS: 943757-71-9 Cat. No.: R468479 Molecular Weight: 325.53 EC Number: 693-884-8

GRADE & PURITY ≥96%

Synonyms

(R)-(+)-alpha,alpha-Diphenyl-2-pyrrolidinemethanol trimethylsilyl ether, 96% | A859453 | (R)-(+)-2-[Diphenyl(trimethylsilyloxy)methyl]pyrrolidine | DTXSID60584871 | (2R)-2-{Diphenyl[(trimethylsilyl)oxy]methyl}pyrrolidine | (r)-(+)-2-(diphenyltrimethylsila

Storage

Store at 2-8°C

Shipped In

Wet ice

Overview

Description

(R)-(+)-α,α-Diphenyl-2-pyrrolidinemethanol trimethylsilyl ether is a diarylprolinol silyl ether organocatalyst.(R)-(+)-α,α-Diphenyl-2-pyrrolidinemethanol trimethylsilyl ether can be used as a catalyst to synthesize:Glycofused tricyclic derivatives, which are used in the development of amyloid β-peptide diagnostic tools.Cyclohexene carbaldehyde derivatives by reacting benzoylnitromethane with aliphatic enals.

Specifications

Synonyms

(R)-(+)-alpha, alpha-Diphenyl-2-pyrrolidinemethanol trimethylsilyl ether, 96% | A859453 | (R)-(+)-2-[Diphenyl(trimethylsilyloxy)methyl]pyrrolidine | DTXSID60584871 | (2R)-2-{Diphenyl[(trimethylsilyl)oxy]methyl}pyrrolidine | (r)-(+)-2-(diphenyltrimethylsila

Specifications & Purity

≥96%

Storage

Store at 2-8°C

Shipped In

Wet ice

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥96%

Names and Identifiers

• Pubchem Sid: 488199300
• Canonical Smiles: C[Si](C)(C)OC(C1CCCN1)(C2=CC=CC=C2)C3=CC=CC=C3
• IUPAC Name: [diphenyl-[(2R)-pyrrolidin-2-yl]methoxy]-trimethylsilane
• InChIKey: RSUHWMSTWSSNOW-LJQANCHMSA-N
• INCHI: 1S/C20H27NOSi/c1-23(2,3)22-20(19-15-10-16-21-19,17-11-6-4-7-12-17)18-13-8-5-9-14-18/h4-9,11-14,19,21H,10,15-16H2,1-3H3/t19-/m1/s1
• Isomeric SMILES: C[Si](C)(C)OC([C@H]1CCCN1)(C2=CC=CC=C2)C3=CC=CC=C3
• Molecular Weight: 325.53
• Reaxy-Rn: 18829165
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=18829165&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Benzenoids
    • Class Benzene and substituted derivatives
      • Subclass Diphenylmethanes

• Kingdom: Organic compounds
• Superclass: Benzenoids
• Class: Benzene and substituted derivatives
• Subclass: Diphenylmethanes
• Intermediate Tree Nodes: Not available
• Direct Parent: Diphenylmethanes
• Alternative Parents: Aralkylamines Trialkylheterosilanes Pyrrolidines Silyl ethers Organic metalloid salts Dialkylamines Azacyclic compounds Organopnictogen compounds Organooxygen compounds Hydrocarbon derivatives
• Molecular Framework: Aromatic heteromonocyclic compounds
• Substituents: Diphenylmethane - Aralkylamine - Pyrrolidine - Trialkylheterosilane - Silyl ether - Secondary aliphatic amine - Organoheterosilane - Secondary amine - Azacycle - Organic metalloid salt - Organoheterocyclic compound - Amine - Organic salt - Organosilicon compound - Hydrocarbon derivative - Organopnictogen compound - Organooxygen compound - Organonitrogen compound - Organic oxygen compound - Organic nitrogen compound - Aromatic heteromonocyclic compound
• Description: This compound belongs to the class of organic compounds known as diphenylmethanes. These are compounds containing a diphenylmethane moiety, which consists of a methane wherein two hydrogen atoms are replaced by two phenyl groups.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Sensitivity: Heat sensitive
• Refractive Index: 1.55
• Specific Rotation[α]: 55° (C=1,CHCl3)
• Molecular Weight: 325.500 g/mol
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 5
• Exact Mass: 325.186 Da
• Monoisotopic Mass: 325.186 Da
• Topological Polar Surface Area: 21.300 Ų
• Heavy Atom Count: 23
• Formal Charge: 0
• Complexity: 348.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 1
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

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