≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Stat5 Inhibitor is a cell permeable nonpetidic nicotinoyl hydrazone which suppresses STAT5 via binding to the SH2 domain. Studies indicate that Stat5 Inhibitor suppresses the SH2 domain of STAT1 and STAT3 to a lesser extent than STAT5 inhibition. In addition, STAT5/STAT5 DNA binding in K562 nuclear extracts are inhibited by Stat5 Inhibitor. STAT5 functions biologically in various processes such as homeostasis of hematopoietic stem cells, development of blood cells, growth hormone effects, and differentiation of mammary epithelium. Stat5 Inhibitor is shown to block STAT5/STAT5 DNA binding activity in K562 nuclear extract and inhibit IFN-α-stimulated STAT5, but not STAT1 or STAT3, tyrosine phosphorylation in Daudi cells.
| Pubchem Sid | 504764823 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/504764823 |
| Canonical Smiles | C1=CC=C2C(=C1)C(=O)C(=CO2)C=NNC(=O)C3=CN=CC=C3 |
| IUPAC Name | N-[(E)-(4-oxochromen-3-yl)methylideneamino]pyridine-3-carboxamide |
| InChIKey | DAVIKTBRCQWOGT-GIJQJNRQSA-N |
| INCHI | 1S/C16H11N3O3/c20-15-12(10-22-14-6-2-1-5-13(14)15)9-18-19-16(21)11-4-3-7-17-8-11/h1-10H,(H,19,21)/b18-9+ |
| Isomeric SMILES | C1=CC=C2C(=C1)C(=O)C(=CO2)/C=N/NC(=O)C3=CN=CC=C3 |
| PubChem CID | 9566174 |
| Molecular Weight | 293.28 |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organoheterocyclic compounds |
| Class | Benzopyrans |
| Subclass | 1-benzopyrans |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Chromones |
| Alternative Parents | Nicotinamides Pyranones and derivatives Benzenoids Heteroaromatic compounds Oxacyclic compounds Carboxylic acids and derivatives Azacyclic compounds Organooxygen compounds Organonitrogen compounds Organic oxides Hydrocarbon derivatives |
| Molecular Framework | Aromatic heteropolycyclic compounds |
| Substituents | Chromone - Nicotinamide - Pyridine carboxylic acid or derivatives - Pyranone - Pyran - Pyridine - Benzenoid - Heteroaromatic compound - Oxacycle - Carboxylic acid derivative - Azacycle - Hydrocarbon derivative - Organic oxide - Organooxygen compound - Organonitrogen compound - Organic oxygen compound - Organic nitrogen compound - Aromatic heteropolycyclic compound |
| Description | This compound belongs to the class of organic compounds known as chromones. These are compounds containing a benzopyran-4-one moiety. |
| External Descriptors | Not available |
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 H2222026 | Certificate of Analysis | Jun 09, 2025 | S339995 |
| H2222027 | Certificate of Analysis | Jun 09, 2025 | S339995 |
| H2222028 | Certificate of Analysis | Jun 09, 2025 | S339995 |
| H2222029 | Certificate of Analysis | Jun 09, 2025 | S339995 |
| Solubility | Soluble in DMSO (25 mg/ml). |
|---|---|
| Refractive Index | n20D1.66 (Predicted) |
| Molecular Weight | 293.280 g/mol |
| XLogP3 | 1.600 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 5 |
| Rotatable Bond Count | 3 |
| Exact Mass | 293.08 Da |
| Monoisotopic Mass | 293.08 Da |
| Topological Polar Surface Area | 80.700 Ų |
| Heavy Atom Count | 22 |
| Formal Charge | 0 |
| Complexity | 501.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 1 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 1 |
| Covalently-Bonded Unit Count | 1 |
