Triton™ X-100 - for electrophoresis , CAS No.9002-93-1

CAS: 9002-93-1 Cat. No.: T109028 Summenformel: C₈H₁₇C₆H₄(OCH₂CH₂)nOH(n≈10) Beilstein Registry Number: 2315025 EG-Nummer: 618-344-0 PubChem CID: 5590

GRADE & PURITY Suitable for electrophoresis

Synonyms

Igepal CA-210 | CAS_118-96-7 | PDSP1_001087 | Ethanol,1,3,3-tetramethylbutyl)phenoxy]- | 2-(4-(2,4,4-Trimethylpentan-2-yl)phenoxy)ethan-1-ol | Octoxynol-1 | Triton X 305 | P-TERT-OCTYLPHENYL (2-HYDROXYETHYL)ETHER | AT25387 | Igepal CA 630 | FT-0673247 | T

Storage

Room temperature

Shipped In

Normal

Übersicht

General description

Triton™ X-100 is a common non-ionic surfactant and emulsifier which is often used in biochemical applications to solubilize proteins. It is considered a comparatively mild detergent, non-denaturing, and is reported in numerous references as a routinely added reagent. It is utilized for lysing cells to extract protein and cellular organelles. It can also permeabilize the living cell membrane for transfection

Application

Triton™ X-100 has been used:

• In immunohistochemistry for staining the Flat-mount retinas

• Along with ice-cold PBS (phosphate buffered saline) in suspension of cells for cell DNA analysis and Annexin V assay

• To permeabilise cells during Immunofluorescent microscopic studies

• As a positive control in LDH assay to determine the cell membrane integrity

• For estimating the lipase activity in postheparin plasma by using modified Belfrage and Vaughan radioenzymatic procedure

• For the preparation of outer membrane protein exctract

• As a component of extraction buffer along with tris-HCl, NaCl, CaCl2, ZnCl2, Brij 35 for homogenization of mice lung cells

• In the treatment of tissue sections for Immunofluorescence labeling

Specifications

Synonyme

Igepal CA-210 | CAS_118-96-7 | PDSP1_001087 | Ethanol,1,3,3-tetramethylbutyl)phenoxy]- | 2-(4-(2,4,4-Trimethylpentan-2-yl)phenoxy)ethan-1-ol | Octoxynol-1 | Triton X 305 | P-TERT-OCTYLPHENYL (2-HYDROXYETHYL)ETHER | AT25387 | Igepal CA 630 | FT-0673247 | T

Spezifikationen & Reinheit

for electrophoresis

Biochemische und physiologische Mechanismen

Widely used non-ionic surfactant for recovery of membrane components under mild non-denaturing conditions.

Rechtliche Informationen

Triton is a trademark of The Dow Chemical Company or an affiliated company of Dow

Storage

Room temperature

Verschickt in

Normal

Note

Für die Elektrophorese geeignet

Namen und Kennungen

Pubchem Sid

508813680

Kanonisches Lächeln

CC(C)(C)CC(C)(C)C1=CC=C(C=C1)OCCO

IUPAC Name

2-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]ethanol

InChIKey

JYCQQPHGFMYQCF-UHFFFAOYSA-N

INCHI

1S/C16H26O2/c1-15(2,3)12-16(4,5)13-6-8-14(9-7-13)18-11-10-17/h6-9,17H,10-12H2,1-5H3

Isomere SMILES

CC(C)(C)CC(C)(C)C1=CC=C(C=C1)OCCO

WGK Deutschland

1

RTECS

MD0907700

Alternative CAS-Nummer

9036-19-5

PubChem CID

5590

UN-Nummer

3082

Beilstein

2315025

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Benzenoids
    • Klasse Benzene and substituted derivatives
      • Subclass Phenylpropanes

• Kingdom: Organic compounds
• Superclass: Benzenoids
• Klasse: Benzene and substituted derivatives
• Subclass: Phenylpropanes
• Intermediate Tree Nodes: Not available
• Direct Parent: Phenylpropanes
• Alternative Parents: Phenoxy compounds Phenol ethers Alkyl aryl ethers Primary alcohols Hydrocarbon derivatives
• Molecular Framework: Aromatic homomonocyclic compounds
• Substituents: Phenylpropane - Phenoxy compound - Phenol ether - Alkyl aryl ether - Ether - Organic oxygen compound - Hydrocarbon derivative - Primary alcohol - Organooxygen compound - Alcohol - Aromatic homomonocyclic compound
• Beschreibung: This compound belongs to the class of organic compounds known as phenylpropanes. These are organic compounds containing a phenylpropane moiety.
• External Descriptors: a small molecule

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

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NR3C1 Tclin Glucocorticoid receptor (14987 Activities)

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KCNH2 Tclin HERG (29587 Activities)

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CYP3A4 Tclin Cytochrome P450 3A4 (53859 Activities)

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HaCaT (4069 Activities)

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Lymphoblastoid cell (5959 Activities)

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TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)

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SMN1 Tchem Survival motor neuron protein (34246 Activities)

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Cruzipain (33337 Activities)

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Plasmodium falciparum (966862 Activities)

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Rattus norvegicus (775804 Activities)

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Nfe2l2 Nuclear factor erythroid 2-related factor 2 (214 Activities)

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Rorc Nuclear receptor ROR-gamma (89407 Activities)

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Wirkungsmechanismen

Chemische und physikalische Eigenschaften

• Brechungsindex: 1.491
• Flammpunkt (°C): 251°C
• Siedepunkt (°C): 270°C
• Schmelzpunkt (°C): 6°C
• Molekulargewicht: 250.380 g/mol
• XLogP3: 4.600
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 6
• Exact Mass: 250.193 Da
• Monoisotopic Mass: 250.193 Da
• Topological Polar Surface Area: 29.500 Ų
• Heavy Atom Count: 18
• Formal Charge: 0
• Complexity: 232.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1