Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA Animal Free,Azide Free,Carrier Free,ExactAb™,Low Endotoxin,Recombinant,Validated for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -80°C,Avoid repeated freezing and thawing Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Dalotuzumab (anti-IGF1R) is a recombinant humanized monoclonal antibody (IgG1 type) targeting IGF-1R. Dalotuzumab (anti-IGF1R) acts by inhibiting IGF-1- and IGF-2-mediated tumor cell proliferation, IGF-1R autophosphorylation, and Akt phosphorylation. Dalotuzumab (anti-IGF1R) also induces apoptosis and cycle arrest. Dalotuzumab (anti-IGF1R) in combination with other anticancer agents such as statins can enhance the antitumor activity of Dalotuzumab (anti-IGF1R) in vitro and in vivo.
Dalotuzumab (anti-IGF1R) (Ab183419) - Flow Cytometry
Flow Cytometry analysis of A549 cells labelling IGF1R (red) with Dalotuzumab (anti-IGF1R) (Ab183419). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.
Dalotuzumab (anti-IGF1R) (Ab183419) - Flow Cytometry
Flow Cytometry analysis of MCF-7 cells labelling IGF1R (red) with Dalotuzumab (anti-IGF1R) (Ab183419). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.
Dalotuzumab (anti-IGF1R) (Ab183419) - Flow Cytometry
Flow Cytometry analysis of HeLa cells labelling IGF1R (red) with Dalotuzumab (anti-IGF1R) (Ab183419). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.
Dalotuzumab (anti-IGF1R) (Ab183419) - SEC
The purity of Dalotuzumab (anti-IGF1R) (Ab183419) is more than 95% verified by HPLC.
Dalotuzumab (anti-IGF1R) (Ab183419) - ELISA
Immobilized Recombinant Human AVItag His-IGF1R-Sino protein at 2.0 μg/mL can bind Dalotuzumab (anti-IGF1R) (Ab183419) with the EC50 of 1.09 ng/mL.
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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Our grade selection guide covers purity, stabilizer status, and application suitability for all variants in our catalog.
View Animal Free grade guide → View Carrier Free grade guide → View Recombinant grade guide → View Validated grade guide → View ExactAb™ grade guide → View Low Endotoxin grade guide → View Azide Free grade guide →
