Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA Animal Free,Azide Free,Carrier Free,ExactAb™,Low Endotoxin,Recombinant,Validated for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -80°C,Avoid repeated freezing and thawing Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Itolizumab (anti-CD6) is a humanized recombinant anti-CD6 monoclonal antibody (MAb) targeting the extracellular SRCR distal domain 1 of CD6. Itolizumab (anti-CD6) reduces T-cell proliferation and inhibits the production of pro-inflammatory cytokines, such as INF-γ, TNFα and IL-6. Itolizumab (anti-CD6) can be used in the research of psoriasis, rheumatoid arthritis (RA), COVID-19.
Purity
>95% (SDS-PAGE&SEC)
Endotoxin Level
< 1.0EU/mg
Itolizumab (anti-CD6) (Ab176610) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling CD6 with Itolizumab (anti-CD6) (Ab176610) conjugated with biotin (right panel) compared with Human IgG (Ab170213) conjugated with biotin - Isotype Control (left panel) and detected with SA-PE (rp156150).
Itolizumab (anti-CD6) (Ab176610) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling CD6 (red) with Itolizumab (anti-CD6) (Ab176610) conjugated with biotin and detected with SA-PE (rp156150). Blue - Isotype control, human IgG (Ab170213) conjugated with biotin. Black - Unlabelled control, cells without incubation with primary antibody.
Itolizumab (anti-CD6) (Ab176610) - Flow Cytometry
Flow Cytometry analysis of MOLT-4 cells labelling CD6 (red) with Itolizumab (anti-CD6) (Ab176610). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.
Itolizumab (anti-CD6) (Ab176610) - Flow Cytometry
Flow Cytometry analysis of Jurkat cells labelling CD6 (red) with Itolizumab (anti-CD6) (Ab176610). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.
Itolizumab (anti-CD6) (Ab176610) - SEC
The purity of Itolizumab (anti-CD6) (Ab176610) is more than 95% verified by HPLC.
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 ZJ23F1202085 | Certificate of Analysis | Dec 20, 2023 | Ab176610 |
| ZJ23F1202084 | Certificate of Analysis | Dec 20, 2023 | Ab176610 |
Our grade selection guide covers purity, stabilizer status, and application suitability for all variants in our catalog.
View Animal Free grade guide → View Carrier Free grade guide → View Recombinant grade guide → View Validated grade guide → View ExactAb™ grade guide → View Low Endotoxin grade guide → View Azide Free grade guide →
