Acetyl chloride - AR, ≥98% , CAS No.75-36-5

CAS: 75-36-5 Cat. No.: A108662 Molecular Weight: 78.5 EC Number: 200-865-6
AVAILABLE TO ORDER
GRADE & PURITY AR ? Analytical Reagent grade — high-purity chemicals meeting strict assay limits for lab analysis. Use when accuracy matters and trace impurities could skew results. ≥98%
Synonyms
Acetic acid chloride | acetylchlorid | acetyl chlorid | EC 200-865-6 | Ethanoyl chloride | UN1717 (DOT) | Acetic acid, chloride | DB14623 | EINECS 200-865-6 | UNII-QD15RNO45K | Acetyl chloride [UN1717] [Flammable liquid] | ACETYL CHLORIDE [MI] | ETHANOIC
Storage
Store at 2-8°C,Argon charged
Shipped In
Wet ice,FedEx DG Service
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
100ml
A108662-100ml
3
$13.90
500ml
A108662-500ml
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$28.90
Enter a quantity for the sizes you want to add.
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Why this grade

AR, ≥98% AR for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at 2-8°C,Argon charged Ships Wet ice,FedEx DG Service Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 48 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Synonyms
Acetic acid chloride | acetylchlorid | acetyl chlorid | EC 200-865-6 | Ethanoyl chloride | UN1717 (DOT) | Acetic acid, chloride | DB14623 | EINECS 200-865-6 | UNII-QD15RNO45K | Acetyl chloride [UN1717] [Flammable liquid] | ACETYL CHLORIDE [MI] | ETHANOIC
Specifications & Purity
AR, ≥98%
Storage
Store at 2-8°C, Argon charged
Shipped In
Wet ice, FedEx DG Service
This product requires cold chain shipping. Ground and other economy services are not available.
Grade
AR
Purity
≥98%
Names and Identifiers
Canonical SmilesCC(=O)Cl
IUPAC Nameacetyl chloride
InChIKeyWETWJCDKMRHUPV-UHFFFAOYSA-N
INCHI1S/C2H3ClO/c1-2(3)4/h1H3
Isomeric SMILES CC(=O)Cl
UN Number 1717
Packing Group II
Molecular Weight 78.5
Reaxy-Rn 605303
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=605303&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganohalogen compounds
ClassAcyl halides
SubclassAcyl chlorides
Intermediate Tree Nodes Not available
Direct ParentAcyl chlorides
Alternative Parents Organochlorides  Organic oxides  Hydrocarbon derivatives  Carbonyl compounds  
Molecular FrameworkAliphatic acyclic compounds
Substituents Acyl chloride - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Organochloride - Carbonyl group - Aliphatic acyclic compound
DescriptionThis compound belongs to the class of organic compounds known as acyl chlorides. These are organic compounds containing the functional group -CO-Cl.
External Descriptors acyl chloride
3D Structure
Interactive Chemical Structure Model





Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

92 results found

Lot NumberCertificate TypeDateItem
F2616512Certificate of AnalysisJun 18, 2026 A108662
F2616511Certificate of AnalysisJun 18, 2026 A108662
F2616510Certificate of AnalysisJun 18, 2026 A108662
F2616508Certificate of AnalysisJun 18, 2026 A108662
H2521210Certificate of AnalysisJun 11, 2026 A108662
B2527141Certificate of AnalysisJun 11, 2026 A108662
L2404144Certificate of AnalysisJun 11, 2026 A108662
B2527136Certificate of AnalysisJun 11, 2026 A108662
E2423145Certificate of AnalysisJun 11, 2026 A108662
A2417068Certificate of AnalysisJun 11, 2026 A108662
J2530199Certificate of AnalysisMay 11, 2026 A108662
K2406216Certificate of AnalysisMay 11, 2026 A108662
A2622172Certificate of AnalysisMay 09, 2026 A108662
A2622169Certificate of AnalysisMay 09, 2026 A108662
D2624502Certificate of AnalysisApr 29, 2026 A108662
D2624501Certificate of AnalysisApr 29, 2026 A108662
D2624500Certificate of AnalysisApr 29, 2026 A108662
D2624499Certificate of AnalysisApr 29, 2026 A108662
I2522107Certificate of AnalysisApr 07, 2026 A108662
A2614155Certificate of AnalysisApr 07, 2026 A108662
J2330095Certificate of AnalysisApr 07, 2026 A108662
J2530197Certificate of AnalysisFeb 05, 2026 A108662
I2522108Certificate of AnalysisJan 19, 2026 A108662
I2522106Certificate of AnalysisJan 19, 2026 A108662
L2501149Certificate of AnalysisDec 05, 2025 A108662
L2501147Certificate of AnalysisDec 04, 2025 A108662
J2530173Certificate of AnalysisNov 04, 2025 A108662
I2522122Certificate of AnalysisSep 23, 2025 A108662
B2527140Certificate of AnalysisSep 10, 2025 A108662
L2404195Certificate of AnalysisSep 10, 2025 A108662
L2404196Certificate of AnalysisSep 10, 2025 A108662
H2521209Certificate of AnalysisAug 29, 2025 A108662
H2521211Certificate of AnalysisAug 22, 2025 A108662
K2406215Certificate of AnalysisAug 11, 2025 A108662
B2527204Certificate of AnalysisMar 03, 2025 A108662
L2404197Certificate of AnalysisDec 13, 2024 A108662
K2406214Certificate of AnalysisNov 08, 2024 A108662
H2427077Certificate of AnalysisAug 28, 2024 A108662
H2427080Certificate of AnalysisAug 28, 2024 A108662
H2427079Certificate of AnalysisAug 28, 2024 A108662
H2427078Certificate of AnalysisAug 28, 2024 A108662
E2423433Certificate of AnalysisMay 27, 2024 A108662
E2423146Certificate of AnalysisMay 27, 2024 A108662
E2423147Certificate of AnalysisMay 27, 2024 A108662
D2417114Certificate of AnalysisMar 27, 2024 A108662
A2417075Certificate of AnalysisJan 25, 2024 A108662
A2417069Certificate of AnalysisJan 22, 2024 A108662
A2417070Certificate of AnalysisJan 22, 2024 A108662
L2308434Certificate of AnalysisDec 19, 2023 A108662
L2308433Certificate of AnalysisDec 19, 2023 A108662
L2308432Certificate of AnalysisDec 19, 2023 A108662
J2330088Certificate of AnalysisNov 03, 2023 A108662
J2330087Certificate of AnalysisNov 03, 2023 A108662
C2407198Certificate of AnalysisNov 03, 2023 A108662
J2330094Certificate of AnalysisNov 02, 2023 A108662
G2307511Certificate of AnalysisJul 13, 2023 A108662
G2311130Certificate of AnalysisJul 12, 2023 A108662
G2311133Certificate of AnalysisJul 12, 2023 A108662
G2311142Certificate of AnalysisJul 12, 2023 A108662
G2307510Certificate of AnalysisJul 12, 2023 A108662
B2322644Certificate of AnalysisJun 06, 2023 A108662
D2310209Certificate of AnalysisApr 15, 2023 A108662
B2322510Certificate of AnalysisFeb 27, 2023 A108662
B2322645Certificate of AnalysisFeb 27, 2023 A108662
B2322675Certificate of AnalysisFeb 27, 2023 A108662
K2217081Certificate of AnalysisNov 23, 2022 A108662
K2217080Certificate of AnalysisNov 23, 2022 A108662
K2217082Certificate of AnalysisNov 22, 2022 A108662
K2217083Certificate of AnalysisNov 22, 2022 A108662
I2223415Certificate of AnalysisSep 30, 2022 A108662
I2223487Certificate of AnalysisSep 30, 2022 A108662
I2223488Certificate of AnalysisSep 29, 2022 A108662
I2223416Certificate of AnalysisSep 29, 2022 A108662
H2210019Certificate of AnalysisAug 16, 2022 A108662
G2216021Certificate of AnalysisJul 19, 2022 A108662
C2211199Certificate of AnalysisJul 14, 2022 A108662
F2222313Certificate of AnalysisJul 05, 2022 A108662
F2222323Certificate of AnalysisJul 05, 2022 A108662
L2123354Certificate of AnalysisApr 26, 2022 A108662
L2123203Certificate of AnalysisApr 26, 2022 A108662
L2123355Certificate of AnalysisApr 26, 2022 A108662
L2123345Certificate of AnalysisApr 26, 2022 A108662
F2222320Certificate of AnalysisApr 21, 2022 A108662
F2222314Certificate of AnalysisApr 21, 2022 A108662
D2219058Certificate of AnalysisApr 21, 2022 A108662
D2219069Certificate of AnalysisApr 21, 2022 A108662
D2219120Certificate of AnalysisApr 21, 2022 A108662
D2220008Certificate of AnalysisApr 21, 2022 A108662
K2119069Certificate of AnalysisMar 08, 2022 A108662
J2114443Certificate of AnalysisFeb 14, 2022 A108662
J2114442Certificate of AnalysisFeb 14, 2022 A108662
J2114427Certificate of AnalysisFeb 14, 2022 A108662

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Chemical and Physical Properties
SolubilityMiscible with Ether,Benzene,Chloroform; Soluble in Acetone
SensitivityHeat and Moisture Sensitive
Refractive Index1.39
Flash Point(°C)(closed cup)4.4°C
Boil Point(°C)52°C
Melt Point(°C)-112°C
Molecular Weight78.500 g/mol
XLogP30.800
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count1
Rotatable Bond Count0
Exact Mass77.9872 Da
Monoisotopic Mass77.9872 Da
Topological Polar Surface Area17.100 Ų
Heavy Atom Count4
Formal Charge0
Complexity33.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Documents & Articles
Friedel–Crafts Acylation
What is Friedel Craft reaction with example?
What are the advantages of Friedel Crafts acylation?
Is Friedel-Crafts alkylation reversible?
How is a Lewis acid used in Friedel Crafts acylation?
What is alkylation of benzene?
Why does nitrobenzene not undergo the Friedel-Crafts acylation reaction?
What are the limitations of Foucault alkylation reaction?
What are the limitations of the Foucault acylation reaction?
Protection Reagents
Reconsidering N-Acyl Amino Protecting Groups: Deprotection Differences, Strategic Roles, and Experimental Selection of Ac, Bz, and Tfa
DMAP Is More Than Just an Organic Base: Experimental Judgment from Nucleophilic Acyl Transfer to Esterification and Macrolactonization
How to Troubleshoot Abnormal Impurities in Peptide Synthesis? Locating Process Issues Through Amino-Related Side Reactions
Citations of This Product
References
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