What are the advantages of Friedel Crafts acylation?
What are the advantages of Friedel Crafts acylation?
posted this at Jun 9, 2025 Updated at Oct 9, 2023
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What are the advantages of Friedel Crafts acylation?
Compared to Friedel-Crafts alkylation, Friedel-Crafts acylation has several advantages: better control of the reaction products, while the acyl ions have a positive charge on the carbon, and are resonance stable, so there is no chance of rearrangement. Using Clemens reduction, the ketones obtained can be reduced to alkyl groups.
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