2-(Dodecylthiocarbonothioylthio)-2-methylpropionic acid N-succinimidyl ester - ≥98% , CAS No.925232-64-0

CAS: 925232-64-0 Cat. No.: N405131 Molecular Weight: 461.69 EC Number: 106-353-8

GRADE & PURITY ≥98%

Synonyms

2-(Dodecylthiocarbonothioylthio)-2-methylpropionic acid N-hydroxysuccinimide ester | N-Hydroxysuccinimide 2-(dodecylthiocarbonothioylthio)isobutyrate | N-Succinimidyl 2-(Dodecylthiocarbonothioylthio)-2-methylpropionate

Storage

Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

Overview

Application：
Functionalized RAFT agent for controlled radical polymerization; especially suited for the polymerization of styrene; acrylate and acrylamide monomers. NHS ester terminus can be used to conjugate to a variety of biomolecules. Chain Transfer Agent (CTA).

Specifications

Synonyms

2-(Dodecylthiocarbonothioylthio)-2-methylpropionic acid N-hydroxysuccinimide ester | N-Hydroxysuccinimide 2-(dodecylthiocarbonothioylthio)isobutyrate | N-Succinimidyl 2-(Dodecylthiocarbonothioylthio)-2-methylpropionate

Specifications & Purity

≥98%

Storage

Store at -20°C, Argon charged

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥98%

Names and Identifiers

• Canonical Smiles: CCCCCCCCCCCCSC(=S)SC(C)(C)C(=O)ON1C(=O)CCC1=O
• IUPAC Name: (2,5-dioxopyrrolidin-1-yl) 2-dodecylsulfanylcarbothioylsulfanyl-2-methylpropanoate
• InChIKey: HKWLQDYVQCZTQP-UHFFFAOYSA-N
• INCHI: 1S/C21H35NO4S3/c1-4-5-6-7-8-9-10-11-12-13-16-28-20(27)29-21(2,3)19(25)26-22-17(23)14-15-18(22)24/h4-16H2,1-3H3
• Isomeric SMILES: CCCCCCCCCCCCSC(=S)SC(C)(C)C(=O)ON1C(=O)CCC1=O
• Molecular Weight: 461.69
• Reaxy-Rn: 27380973
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=27380973&ln=

Chemical and Physical Properties

• Sensitivity: Light Sensitive,Moisture Sensitive,Heat Sensitive
• Melt Point(°C): 101 °C
• Molecular Weight: 461.700 g/mol
• XLogP3: 7.400
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 17
• Exact Mass: 461.173 Da
• Monoisotopic Mass: 461.173 Da
• Topological Polar Surface Area: 146.000 Ų
• Heavy Atom Count: 29
• Formal Charge: 0
• Complexity: 550.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

References

1. Mengfei Ji, Xiaojing Qiu, Lin Hou, Shengnan Huang, Yuanmin Li, Yang Liu, Shaofeng Duan, Yurong Hu.  (2018)  Construction and application of a liver cancer-targeting drug delivery system based on core–shell gold nanocages.  International Journal of Nanomedicine,      [PMID:29606870] [10.2147/IJN.S151043]