Dacetuzumab (anti-CD40) - Anticorpo primario, specific to CD40, Human IgG1, INHIBITOR of Tumor necrosis factor receptor superfamily member 5 inhibitor, INHIBITOR of Tumor necrosis factor receptor superfamily member 5 inhibitor

CAS: 880486-59-9 Cat. No.: Ab183418
Disponibile su ordine
QUALITÀ & PUREZZA Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ≥95%(SDS-PAGE&SEC-HPLC) See COA
Application
Animal Model, ELISA, Flow Cytometry, Functional Assay
Host species
Umano
Reactive species
Umano
Isotype
Human IgG1
Conjugation
Unconjugated
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Dimensione
Germania (EU)
USA*
Prezzo
Qtà
100μg
Ab183418-100μg
—
5 Disponibile
128,34€
1mg
Ab183418-1mg
—
2 Disponibile
635,10€
5mg
Ab183418-5mg
—
1 Disponibile
1.469,86€
10mg
Ab183418-10mg
Su ordinazione · 8–12 settimane
2.353,22€
Enter a quantity for the sizes you want to add.
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Perché questa qualità

Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA Animal Free,Azide Free,Carrier Free,ExactAb™,Low Endotoxin,Recombinant,Validated per flussi di lavoro cromatografici e analitici sensibili che richiedono un'interferenza minima della linea di base.

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Stoccaggio e spedizione

Store at -80°C,Avoid repeated freezing and thawing Spedizione Dry ice packs + Cold packs. Consultare il COA specifico del lotto per le specifiche esatte.

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Documenti di qualità

SDS, COA, scheda tecnica e scheda delle specifiche disponibili per il download. COA specifico del lotto accessibile tramite ricerca per numero di lotto.

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Prova documentale

Citato in 0 pubblicazioni peer-reviewed su cromatografia, sintesi organica e reazioni di accoppiamento incrociato.

Panoramica

Dacetuzumab (anti-CD40) is a humanized IgG1, anti-CD40 monoclonal antibody with anti-lymphoma activity. Dacetuzumab (anti-CD40) kills tumor cells via immune effector functions (antibody-dependent cellular cytotoxicity and phagocytosis [ADCC/ADCP]). Dacetuzumab (anti-CD40) can be used for multiple myeloma research.
Purity
>95% (SDS-PAGE&SEC)
Endotoxin Level
< 1.0EU/mg

Specifiche

Product Name
Dacetuzumab (anti-CD40) - Anticorpo primario, specific to CD40, Human IgG1, INHIBITOR of Tumor necrosis factor receptor superfamily member 5 inhibitor
Sinonimi
AI326936 antibody | B cell associated molecule CD40 antibody | B cell surface antigen CD40 antibody | B cell-associated molecule antibody | B-cell surface antigen CD40 antibody | Bp50 antibody | CD 40 antibody | CD40 antibody | CD40 antigen (TNF receptor
Specifiche e purezza
Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Specie ospite
Umano
Specificità
CD40
Coniugazione
Unconjugated
Grado
Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Tipo di azione
INHIBITOR
Meccanismo d'azione
INHIBITOR of Tumor necrosis factor receptor superfamily member 5 inhibitor
Isotipo
Human IgG1
Tipo di catena leggera
kappa
SDS-PAGE
145 kDa
Metodo di purificazione
Protein A purified
Concentrazione
See COA
CAS
880486-59-9
Product Line
Prodotti biologici
Stoccaggio e spedizione
Forma
Liquid
Condizioni di conservazione di stoccaggio
Store at -80°C,Avoid repeated freezing and thawing
Spedito in
Dry ice packs + Cold packs
Stabilità e conservazione
Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
Immagini

Dacetuzumab (anti-CD40) (Ab183418) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling CD40 with Dacetuzumab (anti-CD40) (Ab183418) conjugated with biotin (right panel) compared with Human IgG (Biotin) (Ab180314) - Isotype Control (left panel) and detected with SA-PE (rp156150).

Dacetuzumab (anti-CD40) (Ab183418) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling CD40 (red) with Dacetuzumab (anti-CD40) (Ab183418) conjugated with biotin and detected with SA-PE (rp156150). Blue - Isotype control, Human IgG (Biotin) (Ab180314). Black - Unlabelled control, cells without incubation with primary antibody.

Dacetuzumab (anti-CD40) (Ab183418) - Flow Cytometry
Flow Cytometry analysis of Raji cells labelling CD40 (red) with Dacetuzumab (anti-CD40) (Ab183418). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

Dacetuzumab (anti-CD40) (Ab183418) - ELISA
Immobilized Recombinant Human CD40 protein (rp183577) at 1.0 μg/mL can bind Dacetuzumab (anti-CD40) (Ab183418) with the EC₅₀ of 30.11 ng/mL.

Dacetuzumab (anti-CD40) (Ab183418) - SEC
The purity of Dacetuzumab (anti-CD40) (Ab183418) is more than 95% verified by HPLC.

Documentazione

📋 Scheda di dati di sicurezza (SDS)

Documento completo su pericoli, manipolazione, stoccaggio e conformità normativa.

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✅ Certificato di analisi (COA)

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🔬 Scheda delle specifiche

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Dati avanzati

Obiettivi associati (umani)
CD40 Tchem Tumor necrosis factor receptor superfamily member 5 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CD40 Tchem Tumor necrosis factor receptor superfamily member 5 (9 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Meccanismi d'azione
Certificati (CoA, COO, BSE/TSE e tabella di analisi)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot NumberCertificate TypeDataOggetto
ZJ24F0910138ZJ24F0910138Certificate of AnalysisJun 17, 2026 Ab183418
ZJ24F0910139ZJ24F0910139Certificate of AnalysisJun 17, 2026 Ab183418
ZJ24F0910140ZJ24F0910140Certificate of AnalysisJun 17, 2026 Ab183418
Calcolatori di soluzioni
Recensioni

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