Guandine thiocyanate - ≥99% , CAS No.593-84-0

CAS: 593-84-0 Cat. No.: G110926 Molecular Weight: 118.16 Beilstein Registry Number: 3563461 EC Number: 209-812-1

GRADE & PURITY ≥99%

Synonyms

Guanidine thiocyanate, >=97% (titration) | Guanidine thiocyanate | Guanidine thiocyanate, BioUltra, for molecular biology, >=99.0% (AT) | GCA2EU297U | AKOS015961014 | Guanidine thiocyanate, >=97.0% (AT) | Guanidine thiocyanate, BioReagent, for molecular b

Storage

Argon charged,Room temperature

Shipped In

Normal

Overview

Guanidine thiocyanate has been used:

· for the lysis of colorectal adenocarcinoma cell line prior to RNA isolation

· as a PCR inhibitor in triplex mitochondrial DNA (mtDNA) qPCR assay

· for DNA extraction from cerebrospinal fluid (CSF)

Specifications

Synonyms

Guanidine thiocyanate, >=97% (titration) | Guanidine thiocyanate | Guanidine thiocyanate, BioUltra, for molecular biology, >=99.0% (AT) | GCA2EU297U | AKOS015961014 | Guanidine thiocyanate, >=97.0% (AT) | Guanidine thiocyanate, BioReagent, for molecular b

Specifications & Purity

≥99%

Biochemical and Physiological Mechanisms

Guanidine thiocyanate (GTC) is a powerful protein denaturant and can denature endogenous ribonucleases.It plays a role in separation of ribosomal ribonucleic acid (rRNA) from ribosomes.GTC in combination with phenol and chloroform can be used in isolation

Storage

Argon charged, Room temperature

Shipped In

Normal

Purity

≥99%

Names and Identifiers

• Pubchem Sid: 504753945
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504753945
• Canonical Smiles: C(#N)S.C(=N)(N)N
• IUPAC Name: guanidine;thiocyanic acid
• InChIKey: ZJYYHGLJYGJLLN-UHFFFAOYSA-N
• INCHI: 1S/CH5N3.CHNS/c2-1(3)4;2-1-3/h(H5,2,3,4);3H
• Isomeric SMILES: C(#N)S.C(=N)(N)N
• WGK Germany: 2
• RTECS: XL1225000
• UN Number: 1759
• Packing Group: III
• Molecular Weight: 118.16
• Beilstein: 3563461
• Reaxy-Rn: 3563461
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=3563461&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organosulfur compounds
    • Class Thiocyanates

• Kingdom: Organic compounds
• Superclass: Organosulfur compounds
• Class: Thiocyanates
• Subclass: Not available
• Intermediate Tree Nodes: Not available
• Direct Parent: Thiocyanates
• Alternative Parents: Organopnictogen compounds Organonitrogen compounds Hydrocarbon derivatives
• Molecular Framework: Not available
• Substituents: Thiocyanate - Organic nitrogen compound - Organopnictogen compound - Hydrocarbon derivative - Organonitrogen compound - Aliphatic acyclic compound
• Description: This compound belongs to the class of organic compounds known as thiocyanates. These are salts or esters of thiocyanic acid, with the general formula RSC#N (R=alkyl, aryl).
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Solubility: Soluble in water and ethanol
• Sensitivity: Hygroscopic,light sensitive
• Melt Point(°C): 118-122°C
• Molecular Weight: 118.160 g/mol
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 0
• Exact Mass: 118.031 Da
• Monoisotopic Mass: 118.031 Da
• Topological Polar Surface Area: 101.000 Ų
• Heavy Atom Count: 7
• Formal Charge: 0
• Complexity: 57.600
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 2

XLogP3

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