Kolliphor® EL - pH range: 6.0-8.0 , CAS No.61791-12-6

CAS: 61791-12-6 Cat. No.: K400327 EC Number: 500-151-7
AVAILABLE TO ORDER
GRADE & PURITY pH range: 6.0-8.0
Synonyms
2-[1,3-bis[2-[(Z)-11-hydroxyheptadec-8-enoxy]carbonyloxyethoxy]propan-2-yloxy]ethyl [(Z)-11-hydroxyheptadec-8-enyl] carbonate
Storage
Room temperature
Shipped In
Normal
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Size
Status
Price
Qty
50g
K400327-50g
≥10
$25.90
250g
K400327-250g
≥10
$61.90
Enter a quantity for the sizes you want to add.
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Why this grade

pH range: 6.0-8.0 for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Room temperature Ships Normal Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 54 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

A derivative of castor oil and ethylene oxide.
Used to emulsify and solubilize oils and other water-insoluble substances. Cremophor is the brand name for a range of non-ionic polyethoxylated detergents. It was originally developed for use as solubilizers and emulsifiers. This research grade product is intended for use in R&D and development only.

Specifications

Synonyms
2-[1, 3-bis[2-[(Z)-11-hydroxyheptadec-8-enoxy]carbonyloxyethoxy]propan-2-yloxy]ethyl [(Z)-11-hydroxyheptadec-8-enyl] carbonate
Specifications & Purity
pH range: 6.0-8.0
Legal Information
Kolliphor is a registered trademark of BASF
Storage
Room temperature
Shipped In
Normal
Names and Identifiers
Pubchem Sid504773672
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/504773672
Canonical SmilesCCCCCCC(CC=CCCCCCCCOC(=O)OCCOCC(COCCOC(=O)OCCCCCCCC=CCC(CCCCCC)O)OCCOC(=O)OCCCCCCCC=CCC(CCCCCC)O)O
IUPAC Name2-[1,3-bis[2-[(Z)-11-hydroxyheptadec-8-enoxy]carbonyloxyethoxy]propan-2-yloxy]ethyl [(Z)-11-hydroxyheptadec-8-enyl] carbonate
InChIKeyLXZHFNATOMRESM-AAKVHIHISA-N
INCHI1S/C63H116O15/c1-4-7-10-31-40-57(64)43-34-25-19-13-16-22-28-37-46-73-61(67)76-51-49-70-55-60(72-53-54-78-63(69)75-48-39-30-24-18-15-21-27-36-45-59(66)42-33-12-9-6-3)56-71-50-52-77-62(68)74-47-38-29-23-17-14-20-26-35-44-58(65)41-32-11-8-5-2/h25-27,34-36,57-60,64-66H,4-24,28-33,37-56H2,1-3H3/b34-25-,35-26-,36-27-
Isomeric SMILES CCCCCCC(O)C/C=C\CCCCCCCOC(=O)OCCOCC(OCCOC(=O)OCCCCCCC/C=C\CC(O)CCCCCC)COCCOC(=O)OCCCCCCC/C=C\CC(O)CCCCCC
WGK Germany 1
RTECS GO5661000

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

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✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

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📊 Datasheet

Quick-reference summary of product specifications and applications.

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🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

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Advanced Data

Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

33 results found

Lot NumberCertificate TypeDateItem
A2627430Certificate of AnalysisJan 19, 2026 K400327
A2627431Certificate of AnalysisJan 19, 2026 K400327
A2627432Certificate of AnalysisJan 19, 2026 K400327
I2523055Certificate of AnalysisOct 16, 2025 K400327
A2404324Certificate of AnalysisOct 11, 2025 K400327
J2511450Certificate of AnalysisSep 27, 2025 K400327
J2511449Certificate of AnalysisSep 27, 2025 K400327
J2511448Certificate of AnalysisSep 27, 2025 K400327
J2511447Certificate of AnalysisSep 27, 2025 K400327
H2301671Certificate of AnalysisMay 09, 2025 K400327
H2301555Certificate of AnalysisMay 09, 2025 K400327
D23141110Certificate of AnalysisJan 09, 2025 K400327
L2419662Certificate of AnalysisDec 12, 2024 K400327
L2419661Certificate of AnalysisDec 12, 2024 K400327
L2419660Certificate of AnalysisDec 12, 2024 K400327
E2428307Certificate of AnalysisMay 20, 2024 K400327
E2428305Certificate of AnalysisMay 20, 2024 K400327
E2428306Certificate of AnalysisMay 20, 2024 K400327
D2417022Certificate of AnalysisDec 23, 2023 K400327
A2404306Certificate of AnalysisDec 23, 2023 K400327
A2404307Certificate of AnalysisDec 23, 2023 K400327
A2404323Certificate of AnalysisDec 23, 2023 K400327
I2504039Certificate of AnalysisDec 23, 2023 K400327
L2125444Certificate of AnalysisSep 22, 2023 K400327
H2301751Certificate of AnalysisJul 05, 2023 K400327
H2301554Certificate of AnalysisJul 05, 2023 K400327
L2307136Certificate of AnalysisJul 05, 2023 K400327
H2301668Certificate of AnalysisJul 05, 2023 K400327
H2301660Certificate of AnalysisJul 05, 2023 K400327
D2327035Certificate of AnalysisDec 14, 2021 K400327
D23141138Certificate of AnalysisDec 14, 2021 K400327
L2214041Certificate of AnalysisDec 14, 2021 K400327
F2327410Certificate of AnalysisDec 14, 2021 K400327

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Chemical and Physical Properties
Flash Point(°C)257°C
Documents & Articles
Citations of This Product
References
1. Xiaoqiang Zeng, Hongwu Sun, Yan Ye, Xing Luo, Dingyi Cai, Yun Yang, Ting Chen, Cun Sun, Shaotong Zhang, Hao Zeng.  (2023)  Evaluating the Immune Response of a Nanoemulsion Adjuvant Vaccine Against Methicillin-Resistant Staphylococcus aureus (MRSA) Infection.  Jove-Journal of Visualized Experiments,      [PMID:37677037] [10.3791/65152]
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20. Da-xia Zhang, Xian-peng Zhang, Jian Luo, Bei-xing Li, Yan Wei, Feng Liu.  (2018)  Causation Analysis and Improvement Strategy for Reduced Pendimethalin Herbicidal Activity in the Field after Encapsulation in Polyurea.  ACS Omega,      [PMID:31457926] [10.1021/acsomega.7b01651]
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36. Huang Xingzhen, Feng Lizhen, Lu Xuefang, Yang Fan, Liu Shengjun, Wei Xueqian, Huang Jinping, Wang Yao, Huang Dongyi, Huang Tingting.  (2024)  Development and optimization of a self micro-emulsifying drug delivery system (SMEDDS) for co-administration of sorafenib and curcumin.  Drug Delivery and Translational Research,      [PMID:39207633] [10.1007/s13346-024-01699-3]
37. Dihao Xie, Simin Zhong, Meixue Luo, Jiahao Xu, Ruoyan Zheng, Jiading Luo, Yiting Wang, Yongxing Guo, Lianxia Guo, Baojian Wu, Danyi Lu.  (2024)  Disruption of local circadian clocks in aristolochic acid-induced nephropathy in mice.  PHYTOMEDICINE,      [PMID:39541665] [10.1016/j.phymed.2024.156235]
38. Yinglan Li, Qipeng Wei, Jianshuo Su, Huaizhen Zhang, Zhiping Fan, Zhuang Ding, Min Wen, Min Liu, Yanna Zhao.  (2024)  Encapsulation of astaxanthin in OSA-starch based amorphous solid dispersions with HPMCAS-HF/Soluplus® as effective recrystallization inhibitor.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:39349321] [10.1016/j.ijbiomac.2024.135421]
39. Zou Zhihui, Xue Yuanyuan, Adu-Frimpong Michael, Wang ChengWei, Jin Zhou, Xu Ying, Yu Jiangnan, Xu Ximing, Zhu Yuan.  (2024)  Formononetin-Loaded Self-Microemulsion Drug Delivery Systems for Improved Solubility and Oral Bioavailability: Fabrication, Characterization, In Vitro and In Vivo Evaluation.  AAPS PHARMSCITECH,  25  (8): (1-18).  [PMID:39487315] [10.1208/s12249-024-02975-8]
40. Fangqi Cao, Shuchen Yu, Xiujuan Chen, Lu Xiao, Tingting Qiu, Xiru Wang, Daiwen Zhang, Xiaoliang Yuan, Ping Shi.  (2024)  Identification and pharmacological properties of 2-(1H-indazole-3-carboxamido)-3,3-dimethylbutanoate (MDMB-INACA), N-(1-amino-3,3-dimethyl-1-oxobutan-2-yl)-1H-indazole-3-carboxamide (ADB-INACA), and N-(1-amino-3,3-dimethyl-1-oxobutan-2-yl)-1-hexyl-1H-indazole-3-carboxamide (ADB-HINACA).  JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS,      [PMID:39616837] [10.1016/j.jpba.2024.116566]
41. Tingting Zhang, Congcong Zhang, Xue Li, Dongfang Ren, Mingshuang Zheng, Shuo Zhang, Fangping Yuan, Xin Du, Zhenguo Zhang.  (2024)  Inflammation assessment and therapeutic monitoring based on highly sensitive and multi-level electrochemical detection of PGE2.  BIOSENSORS & BIOELECTRONICS,      [PMID:38950517] [10.1016/j.bios.2024.116539]
42. Dongyan Duan, Hua Xie, Jiayi Jiang, Ping Yang, Zhiyuan Guo, Xiaoqiang Guo, Xingyu Chen, Qian Yao.  (2025)  Permeability-Enhancing and Protective Effect on Small Intestine of Punicic Acid in Different Forms and Their Nanoemulsions With Low Toxicity.  International Journal of Nanomedicine,      [PMID:39931527] [10.2147/IJN.S486709]
43. Haimei Li, Xinjia Tan, Liyan Qin, Mansour K. Gatasheh, Lei Zhang, Wenmin Lin, Feng Hu, Rian Yan, Mariam K. Alshammri, Yingbin Shen, Arshad Mehmood Abbasi, Jing Qi.  (2024)  Preparation, process optimisation, stability and bacteriostatic assessment of composite nanoemulsion containing corosolic acid.  Heliyon,      [PMID:39386795] [10.1016/j.heliyon.2024.e38283]
44. Jiamin Mao, Xiaoyuan Liu, Lie Zhang, Yu Chen, Shiyu Zhou, Yujiao Liu, Jing Ye, Xiaohong Xu, Quan Zhang.  (2024)  Self-Nanoemulsifying Drug Delivery System of Morin: A New Approach for Combating Acute Alcohol Intoxication.  International Journal of Nanomedicine,      [PMID:39439503] [10.2147/IJN.S472287]
45. Li Wang, Jianlu Qu, Zixuan Yan, Cunhao Li, Xingchu Gong, Wenlong Li.  (2025)  Design of a self-assembled curcumin nanoemulsion and construction of a micropellet delivery system for enhanced stability.  COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS,      [PMID:] [10.1016/j.colsurfa.2025.138370]
46. Yongjing Li, Jiaxun Wan, Fang Wang, Jia Guo, Changchun Wang.  (2019)  Effect of increasing liver blood flow on nanodrug clearance by the liver for enhanced antitumor therapy.  Biomaterials Science,  (4): (1507-1515).  [PMID:30675877] [10.1039/C8BM01371C]
47. Tianchen Zhang, Yijiao Xue, Fei Song, Zheng Pan, Meng Zhang, Yonghong Zhou.  (2024)  Vibration-damping, fire-retardant, smoke-suppressing, and anti-dripping bio-based polyurethane composites enabled by functionalized UiO-66-NH2 nanomaterials.  COMPOSITES PART B-ENGINEERING,      [PMID:] [10.1016/j.compositesb.2024.112046]
48. Hongxing Ma, Mingjuan Chu, Kiyoshi Itagaki, Ping Xin, Xuegang Zhou, Dawei Zhang, Youzhi Wang, Jia Fu, Shiqin Sun.  (2014)  Formulation and in Vitro Characterization of a Novel Solid Lipid-Based Drug Delivery System.  CHEMICAL & PHARMACEUTICAL BULLETIN,  62  (12): (1173-1179).  [PMID:25450625] [10.1248/cpb.c14-00339]
49. Jiayu Song, Huanhuan Zhang, Xiaohui Zhang, Meiying Liu, Dan Peng, Yuan Ren, Yan Sun, Yunlan Li.  (2025)  Galactose-modified erythrocyte membrane fusion liposomes enable the targeted delivery of drug nanoparticles to the liver.  RSC Advances,  15  (22): (17781-17794).  [PMID:40443690] [10.1039/D4RA07489K]
50. Yaxin Zheng, Qing Zhou, Hailong Ma, Hongling Xu, Can Yin, Yihong Su, Yuyang Li, Yang Li.  (2025)  Revealing the Incidence of the Accelerated Blood Clearance Phenomenon of PEGylated Liposomes in Individuals Using a Drug-Release Reporter Liposome.  Small,      [PMID:40552565] [10.1002/smll.202500526]
51. Yu Chun Wang, Shuai Ding, Ya Feng Wang, Han Xie, Shan Shan Liu, Hong Wei Chen, Dan Wu, Ying Xie, Xin Wen, Yi Zhun Zhu, Ling Yun Sun.  (2025)  A Potential Approach of Mesenchymal Stem Cells Combined Silybin for Synergistic Treatment in Rheumatoid Arthritis via ICOS/ICOSL.  MedComm,  (11): (e70450).  [PMID:41164800] [10.1002/mco2.70450]
52. Liang Liu, Huaiyu Zhang, Junjie Wang, Yueli Zhou, Dayuan Chen, Ya Yang, Jing Li, Haotian Ma, Zhao-Jun Wei.  (2026)  Ursolic acid nanoemulsion system for inhibition of goji berry black mold caused by Alternaria alternata.  FOOD CHEMISTRY,      [PMID:41579538] [10.1016/j.foodchem.2026.148066]
53. Yutong Ding, Jiayi Gong, Ping Yang, Zhengxi Zhao, Zhenglu Jiang, Xinru Yang, Meisha Xu, Xiaoqiang Guo, Yun Yan, Qian Yao.  (2026)  Punicic acid ethyl ester, a superior absorption-enhancer over pomegranate seed oil, dramatically improves quercetin bioavailability via strong interaction and rapid lipolysis.  International Journal of Pharmaceutics-X,      [PMID:41675219] [10.1016/j.ijpx.2026.100499]
54. Juan Tao, Yuning Wei, Mengyu Zhao, Zirong Dong, Zibo Wei, Shuyan Li, Jiaxin Zhao, Jinlong Yang, Jianping Qi.  (2026)  Overcoming mucus trapping by engineering PEGylated self-nanoemulsions for enhanced oral absorption of a novel AMPK activator.  INTERNATIONAL JOURNAL OF PHARMACEUTICS,      [PMID:41740768] [10.1016/j.ijpharm.2026.126704]
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