GRADE & PURITYRecombinant?Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin.Validated?Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated.ExactAb™?ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications.0.5 mg/mL
ExactAb™, Validated, Recombinant, 0.5 mg/mL ExactAb™,Recombinant,Validated for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping
Store at -20°C,Avoid repeated freezing and thawing Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
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Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Overview
Rabbit anti Human Mad2L2/REV7 Antibody, Recombinant, could be used for WB, IF, ICC and so on.
Application: WB: 1/500-1/1000 ICC/IF: 1/50-1/200
Protein Function： Adapter protein able to interact with different proteins and involved in different biological processes. Mediates the interaction between the error-prone DNA polymerase zeta catalytic subunit REV3L and the inserter polymerase REV1, thereby mediating the second polymerase switching in translesion DNA synthesis. Translesion DNA synthesis releases the replication blockade of replicative polymerases, stalled in presence of DNA lesions. May also regulate another aspect of cellular response to DNA damage through regulation of the JNK-mediated phosphorylation and activation of the transcriptional activator ELK1. Inhibits the FZR1- and probably CDC20-mediated activation of the anaphase promoting complex APC thereby regulating progression through the cell cycle. Regulates TCF7L2-mediated gene transcription and may play a role in epithelial-mesenchymal transdifferentiation.
Specifications
Product Name
Recombinant Mad2L2/REV7 Antibody - Primary antibody, specific to MAD2L2, Rabbit IgG
Synonyms
hREV7 | MAD2-like protein 2 | Mitotic arrest deficient 2-like protein 2 | REV7 homolog | Homolog of REV7 S cerevisiae | HREV7 | MAD2 homolog | MAD2 like 2 | MAD2 mitotic arrest deficient like 2 | MAD2B | Mitotic Arrest Deficient 2 L2 | Mitotic arrest defi
Specifications & Purity
ExactAb™, Validated, Recombinant, 0.5 mg/mL
Host species
Rabbit
Specificity
MAD2L2
Immunogen
A synthetic peptide derived from human Mad2L2 (AA 178-191)
Positive Control
WB: Jurkat, K562, HeLa, MOLT-4 and SK-N-SH cell lysates. ICC/IF: HeLa cells.
Conjugation
Unconjugated
Grade
ExactAb™, Recombinant, Validated
Isotype
Rabbit IgG
SDS-PAGE
150 kDa
Purification Method
Immunogen affinity purified
Concentration
0.5 mg/mL
Storage and Shipping
Shape
Liquid
Storage
Store at -20°C,Avoid repeated freezing and thawing
Shipped In
Ice chest + Ice pads
Stability And Storage
Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
Images
Recombinant Mad2L2/REV7 Antibody (Ab113958) - Western Blot All lanes: Recombinant Mad2L2/REV7 Antibody (Ab113958) at 1/1000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 24 kDa Observed band size: 24 kDa Exposure time: 30.0 s
Recombinant Mad2L2/REV7 Antibody (Ab113958) - IF/ICC Immunocytochemistry analysis of Mad2L2/REV7 (green) in HeLa using Recombinant Mad2L2/REV7 Antibody (Ab113958), and cells were counterstained with DAPI (blue).
Application
Application
Dilution info
WB
1/500-1/1000
IF/ICC
1/50-1/200
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
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