Trastuzumab emtansine (anti-ERBB2) - Primary antibody, specific to ERBB2, Human IgG1, INHIBITOR of Receptor protein-tyrosine kinase erbB-2 inhibitor, INHIBITOR of Receptor protein-tyrosine kinase erbB-2 inhibitor
Trastuzumab emtansine (anti-ERBB2) - Primary antibody, specific to ERBB2, Human IgG1, INHIBITOR of Receptor protein-tyrosine kinase erbB-2 inhibitor, INHIBITOR of Receptor protein-tyrosine kinase erbB-2 inhibitor
GRADE & PURITYAnimal Free?Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material.Carrier Free?Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays.Recombinant?Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin.Validated?Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated.ExactAb™?ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications.Low Endotoxin?Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere.Azide Free?Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory.≥90%(SDS-PAGE&SEC-HPLC)See COA
Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥90%(SDS-PAGE&SEC-HPLC), See COA Animal Free,Azide Free,Carrier Free,ExactAb™,Low Endotoxin,Recombinant,Validated for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping
Store at -80°C,Avoid repeated freezing and thawing Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
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Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Overview
Trastuzumab emtansine (anti-ERBB2) is an antibody-drug conjugate (ADC) that incorporates the HER2-targeted antitumor properties of trastuzumab with the cytotoxic activity of the microtubule-inhibitory agent DM1 (derivative of maytansine). Trastuzumab emtansine (anti-ERBB2) can be used for the research of advanced breast cancer.
Specifications
Product Name
Trastuzumab emtansine (anti-ERBB2) - Primary antibody, specific to ERBB2, Human IgG1, INHIBITOR of Receptor protein-tyrosine kinase erbB-2 inhibitor
INHIBITOR of Receptor protein-tyrosine kinase erbB-2 inhibitor
Isotype
Human IgG1
Light Chain Type
kappa
SDS-PAGE
145 kDa
Purification Method
Protein A purified
Concentration
See COA
CAS
1018448-65-1
Storage and Shipping
Shape
Liquid
Storage
Store at -80°C,Avoid repeated freezing and thawing
Shipped In
Dry ice packs + Cold packs
Stability And Storage
Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
Images
Trastuzumab emtansine (anti-ERBB2) (Ab175686) - Flow Cytometry Flow Cytometry analysis of MCF7 cells labelling ERBB2 (red) with Trastuzumab emtansine (anti-ERBB2) (Ab175686) at 1.0 μg/mL for 1 hour at 4°C. Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.
Trastuzumab emtansine (anti-ERBB2) (Ab175686) - ELISA Immobilized Recombinant Human ErbB2/HER2 protein (rp169607) at 1.0 μg/mL can bind Trastuzumab emtansine (anti-ERBB2) (Ab175686) with the EC₅₀ of 138.5 ng/mL.
Trastuzumab emtansine (anti-ERBB2) (Ab175686) - SEC The purity of Trastuzumab emtansine (anti-ERBB2) (Ab175686) is more than 95% verified by HPLC.
Trastuzumab emtansine (anti-ERBB2) (Ab175686) - SEC-MS The drug-to-antibody ratio (DAR) of the Trastuzumab emtansine (anti-ERBB2) (Ab175686) is 3.3.
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
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