Topic

Tumors

Browse protocols, FAQs, guidelines, and technical articles tagged “Tumors”, newest first. For research use only.

5 resources · protocols, FAQs, guidelines & articles
Article

From Tumor Sequencing to “One Patient, One Drug”: Machine-Learning-Assisted Design of V940 Individualized Neoantigen mRNA and the Phase III Breakthrough in Melanoma

On August 19, 2026, Merck and Moderna announced positive topline results from a Phase III clinical trial in melanoma. The study evaluated a patient-specific messenger RNA (mRNA) neoantigen therapy in combination with pembrolizumab. The therapy was previously designated mRNA-4157/V940 during ...

Updated ·29 min read
Article

New Progress in the Solid-Phase Synthesis of Sterically Hindered Peptides: Background, Core Breakthroughs, and Implications for Automation Compatibility of the RMMR Strategy

Peptides have become an important class of molecules in modern medicinal chemistry and chemical biology. Compared with traditional small molecules, peptides often offer higher target selectivity and stronger molecular recognition capability, while still retaining good structural tunability. As a ...

Updated ·22 min read
Article

VEGFR Inhibitors

Vascular endothelial growth factor receptor (VEGFR) inhibitors are a class of compounds that block signaling through VEGF receptor tyrosine kinases. VEGFR plays a central role in angiogenesis, the formation of new blood vessels, which is a critical process in tumor growth and progression.

Updated ·2 min read

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