GRADE & PURITYBioReagent?BioReagent grade — tested suitable for life-science and molecular-biology use. Use for cell culture, assays, and biochemical work needing biological compatibility.
BioReagent BioReagent for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
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Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Overview
Cytosolic Isocitrate Dehydrogenase (EC 1.1.1.42) is widely distributed in animals, plants, microorganisms, and cultured cells. It catalyzes the oxidative decarboxylation of isocitrate to produce α-ketoglutarate while simultaneously reducing NADP⁺ to NADPH. ICDHc serves as another important source of NADPH in the cytoplasm, in addition to the pentose phosphate pathway, and its activity typically undergoes significant changes under stress conditions.
Assay Principle: The activity is determined by measuring the increase in NADPH concentration at 340 nm, which results from the ICDHc-catalyzed reduction of NADP⁺.
Storage and Shipping
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
Stability And Storage
Store at -20℃ for 6 months.
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
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