Formamide - Moligand™, ACS, ≥99.5% , CAS No.75-12-7

CAS: 75-12-7 Cat. No.: F120616 Formula: CH₃NO Molecular Weight: 45.04 Beilstein Registry Number: 505995 EC Number: 200-842-0

GRADE & PURITY Moligand™, ACS, ≥99.5%

Synonyms

Methanamide | Methanamid | DTXSID8025337 | HSDB 88 | Formimidic acid | Methanimidic acid | Amid kyseliny mravenci | formamide | Formic amide | CCRIS 6240 | formamid | carbamaldehyde | NSC 748 | Amid kyseliny mravenci [Czech] | Formic acid, amide | Methano

Storage

Room temperature,Argon charged

Shipped In

Normal

Overview

The addition of formamide may enhance the specificity and efficiency of amplification of PCR (polymerase chain reaction).It may be used as an ammonia equivalent for the palladium-catalyzed aminocarbonylation of 1-bromo-3-trifluoromethylbenzene to form 3-(trifluoromethyl)benzamide.

Formamide destabilizes nucleic acid duplexes and may be used, typically, at a concentration of 50%, in hybridization protocols requiring lower hybridization

Specifications

Synonyms

Methanamide | Methanamid | DTXSID8025337 | HSDB 88 | Formimidic acid | Methanimidic acid | Amid kyseliny mravenci | formamide | Formic amide | CCRIS 6240 | formamid | carbamaldehyde | NSC 748 | Amid kyseliny mravenci [Czech] | Formic acid, amide | Methano

Specifications & Purity

Moligand™, ACS, ≥99.5%

Storage

Room temperature,Argon charged

Shipped In

Normal

Grade

ACS, Moligand™

Purity

≥99.5%

Names and Identifiers

Pubchem Sid

488179541

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/488179541

Canonical Smiles

C(=O)N

IUPAC Name

formamide

InChIKey

ZHNUHDYFZUAESO-UHFFFAOYSA-N

INCHI

1S/CH3NO/c2-1-3/h1H,(H2,2,3)

Isomeric SMILES

C(=O)N

WGK Germany

1

RTECS

LQ0525000

Alternate CAS

75-12-7,28704-51-0

NSC Number

748

MeSH Entry Terms

formamide

Molecular Weight

45.04

Beilstein

505995

Reaxy-Rn

505995

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=505995&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Class Carboximidic acids and derivatives
      • Subclass Carboximidic acids

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Class: Carboximidic acids and derivatives
• Subclass: Carboximidic acids
• Intermediate Tree Nodes: Not available
• Direct Parent: Carboximidic acids
• Alternative Parents: Organopnictogen compounds Organooxygen compounds Imines Hydrocarbon derivatives
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Carboximidic acid - Organic nitrogen compound - Organic oxygen compound - Organopnictogen compound - Hydrocarbon derivative - Organooxygen compound - Organonitrogen compound - Imine - Aliphatic acyclic compound
• Description: This compound belongs to the class of organic compounds known as carboximidic acids. These are organic acids with the general formula RC(=N)-OH (R=H, organic group).
• External Descriptors: a small molecule

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Mechanisms of Action

Chemical and Physical Properties

• Sensitivity: Moisture sensitive.
• Freezing Point(°C): 2 °C
• Refractive Index: 1.447
• Flash Point(°F): 347℉
• Flash Point(°C): 175℃
• Boil Point(°C): 210°C
• Melt Point(°C): 2-3°C
• Molecular Weight: 45.041 g/mol
• XLogP3: -0.800
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 45.0215 Da
• Monoisotopic Mass: 45.0215 Da
• Topological Polar Surface Area: 43.100 Ų
• Heavy Atom Count: 3
• Formal Charge: 0
• Complexity: 12.300
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1