GRADE & PURITYValidated?Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated.ExactAb™?ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications.1.0 mg/mL
ExactAb™, Validated, 1.0 mg/mL ExactAb™,Validated for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping
Store at -20°C,Avoid repeated freezing and thawing Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
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Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Overview
Rabbit anti Human hnRNP D Antibody, Polyclonal, could be used for WB, IHC, ICC, IF and so on. Application: WB: 1/500-1/2000 IHC: 1/100-1/300 ICC/IF: 1/200-1/1000 Protein Function Binds with high affinity to RNA molecules that contain AU-rich elements (AREs) found within the 3'-UTR of many proto-oncogenes and cytokine mRNAs. Also binds to double- and single-stranded DNA sequences in a specific manner and functions a transcription factor. Each of the RNA-binding domains specifically can bind solely to a single-stranded non-monotonous 5'-UUAG-3' sequence and also weaker to the single-stranded 5'-TTAGGG-3' telomeric DNA repeat. Binds RNA oligonucleotides with 5'-UUAGGG-3' repeats more tightly than the telomeric single-stranded DNA 5'-TTAGGG-3' repeats. Binding of RRM1 to DNA inhibits the formation of DNA quadruplex structure which may play a role in telomere elongation. May be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain.
Specifications
Product Name
hnRNP D/AUF1 Antibody - Primary antibody, specific to HNRNPD, Rabbit IgG
Synonyms
ARE binding protein AUFI type A antibody | AU-rich element RNA-binding protein 1 antibody | AUF antibody | AUF1 antibody | AUF1A antibody | Heterogeneous nuclear ribonucleoprotein D0 antibody | hnRNP D antibody | hnRNP D0 antibody | Hnrnpd antibody | hnRN
Specifications & Purity
ExactAb™, Validated, 1.0 mg/mL
Host species
Rabbit
Specificity
HNRNPD
Immunogen
Synthesized peptide derived from human hnRPD (AA 49-98)
Positive Control
WB: HEK293, Jurkat, HeLa, U2OS, K562, NIH/3T3 and C6 cell lysates. IHC: Human lung carcinoma tissue. ICC/IF: HeLa cells.
Conjugation
Unconjugated
Grade
ExactAb™, Validated
Isotype
Rabbit IgG
SDS-PAGE
150 kDa
Purification Method
Immunogen affinity purified
Concentration
1.0 mg/mL
Storage and Shipping
Shape
Liquid
Storage
Store at -20°C,Avoid repeated freezing and thawing
Shipped In
Ice chest + Ice pads
Stability And Storage
Store at -20°C long term (12 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
Images
hnRNP D/AUF1 Antibody (Ab108424) - Western Blot All lanes: hnRNP D/AUF1 Antibody (Ab108424) at 1/2000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 38 kDa Observed band size: 35 kDa Exposure time: 39.8 s
hnRNP D/AUF1 Antibody (Ab108424) - IF/ICC Immunofluorescence analysis of HeLa cells, using hnRNP D/AUF1 Antibody (Ab108424). The picture on the right is blocked with the synthesized peptide.
hnRNP D/AUF1 Antibody (Ab108424) - IHC Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using hnRNP D/AUF1 Antibody (Ab108424). The picture on the right is blocked with the synthesized peptide.
Application
Application
Dilution info
WB
1/500-1/2000
IF/ICC
1/200 - 1/1000
IHC
1/100-1/300
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
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