Trimethylsilyl cyanide（TMSCN） - ≥96% , CAS No.7677-24-9

CAS: 7677-24-9 Cat. No.: T106618 Molecular Weight: 99.21 Beilstein Registry Number: 1737612 EC Number: 231-657-3 PubChem CID: 82115

GRADE & PURITY ≥96%

Synonyms

TMSCN | Cyanotrimethylsilane | cyanotrimethyl-silane | Trimethyl silyl nitrile | trimethysilyl cyanide | EN300-29571 | LS-06137 | Trimethylsilanecyanide | Trimethylsilylcyanide,99% | T0990 | DTXSID9064766 | Trimethylsilyl cyanide, 98% | Crystal Scarlet 6R

Storage

Store at 2-8°C,Argon charged

Shipped In

Wet ice

Specifications

Synonyms

TMSCN | Cyanotrimethylsilane | cyanotrimethyl-silane | Trimethyl silyl nitrile | trimethysilyl cyanide | EN300-29571 | LS-06137 | Trimethylsilanecyanide | Trimethylsilylcyanide, 99% | T0990 | DTXSID9064766 | Trimethylsilyl cyanide, 98% | Crystal Scarlet 6R

Specifications & Purity

≥96%

Storage

Store at 2-8°C, Argon charged

Shipped In

Wet ice

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥96%

Names and Identifiers

• Canonical Smiles: C[Si](C)(C)C#N
• IUPAC Name: trimethylsilylformonitrile
• InChIKey: LEIMLDGFXIOXMT-UHFFFAOYSA-N
• INCHI: 1S/C4H9NSi/c1-6(2,3)4-5/h1-3H3
• Isomeric SMILES: C[Si](C)(C)C#N
• WGK Germany: 3
• PubChem CID: 82115
• UN Number: 3383
• Molecular Weight: 99.21
• Beilstein: 1737612

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organometallic compounds
    • Class Organometalloid compounds
      • Subclass Organosilicon compounds
        • Level5 Alkylsilanes
          • Level6 Trialkylsilanes

• Kingdom: Organic compounds
• Superclass: Organometallic compounds
• Class: Organometalloid compounds
• Subclass: Organosilicon compounds
• Intermediate Tree Nodes: Alkylsilanes
• Direct Parent: Trialkylsilanes
• Alternative Parents: Organic metalloid salts Organopnictogen compounds Organonitrogen compounds Hydrocarbon derivatives
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Trialkylsilane - Organic metalloid salt - Organic nitrogen compound - Organopnictogen compound - Hydrocarbon derivative - Organic salt - Organonitrogen compound - Aliphatic acyclic compound
• Description: This compound belongs to the class of organic compounds known as trialkylsilanes. These are organosilicon compounds containing exactly one alkyl chain attached to the silicon atom.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Solubility: Miscible with organic solvents.
• Sensitivity: Moisture & Heat sensitive
• Freezing Point(°C): 10 °C
• Refractive Index: 1.388-1.392
• Flash Point(°F): 33.8 °F
• Flash Point(°C): 1℃
• Boil Point(°C): 114-117°C
• Melt Point(°C): 11°C
• Molecular Weight: 99.210 g/mol
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 99.0504 Da
• Monoisotopic Mass: 99.0504 Da
• Topological Polar Surface Area: 23.800 Ų
• Heavy Atom Count: 6
• Formal Charge: 0
• Complexity: 81.500
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

XLogP3

References

1. Jinsheng Lin, Feifei Chen, Chaohua Bao, Jian Ma, Dan Li, Lewei Zheng, Wenquan Zhu, Wenbin Chen, Xiaoming Liu.  (2021)  Investigation of an artificial solution degradant of linagliptin: An undesired linagliptin urea derivative generates in sample preparation of linagliptin tablet treated by sonication in acetonitrile containing diluent.  JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS,      [PMID:34954487] [10.1016/j.jpba.2021.114540]

2. Shuang Xu, Ai-Min Pang, Zhuo Wu, Hai-Tao Li, Wei Li, Jie Kong.  (2021)  Synthesis of Polyetheramine Based Bonding Agents and Their Effect on Mechanical Properties of an AP/CL-20/GAP Formulation.  PROPELLANTS EXPLOSIVES PYROTECHNICS,  46  (8): (1216-1226).  [PMID:] [10.1002/prep.202000206]

3. Li Jie, Shang Shuxia, Lin Zhengguo, Yao Zishuo, Zhen Ni, Li Zhen, Chi Yingnan, Hu Changwen.  (2020)  Assembly of Lanthanide-Containing Tungstotellurates(VI): Syntheses, Structures, and Catalytic Properties.  Frontiers in Chemistry,      [PMID:33330390] [10.3389/fchem.2020.598961]

4. Jinsheng Lin, Tianpei Huang, Mengxue Feng, Dan Li, Danna Zhao, Jichao Wang, Jianyang Jin, Wenquan Zhu, Min Li.  (2019)  Solution degradant of mirabegron extended release tablets resulting from a Strecker-like reaction between mirabegron, minute amounts of hydrogen cyanide in acetonitrile, and formaldehyde in PEG during sample preparation.  JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS,      [PMID:30818256] [10.1016/j.jpba.2019.01.045]

5. Lulu Wang, Minxin Yang, Xiaochong Liu, He Song, Lu Han, Wenyi Chu, Zhizhong Sun.  (2016)  Pd-catalyzed direct C?H cyanation of picolinamides via bidentate chelation assistance.  APPLIED ORGANOMETALLIC CHEMISTRY,  30  (8): (680-683).  [PMID:] [10.1002/aoc.3489]

6. Kangyu Zhao, Mengfei Xie, Xin Long, Ping Lan, Zizhe Cai, Yong Wang.  (2025)  Synergistic interaction between maillard reaction product and γ-tocopherol in enhancing the oxidation stability of flaxseed oil.  FOOD RESEARCH INTERNATIONAL,      [PMID:41074373] [10.1016/j.foodres.2025.117140]