Determine the necessary mass, volume, or concentration for preparing a solution.
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Moligand™, ≥99% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at 2-8°C Ships Wet ice Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 34 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
5-Fluoro-2′-deoxyuridine, also called floxuridine elicits DNA-directed cytotoxicity in cancer cells. Floxuridine is effective for treating liver cancer and eliminating virulence of Staphylococcus aureus. Dipeptide prodrugs combination of floxuridine with gemcitabine are more cell permeable and display enhanced anti-proliferative activity. Floxuridine is effective on solid tumours and advanced stage cancers.
5-Fluoro-2′-deoxyuridine has been used as a mitotic inhibitor in schwann cell proliferation, glia proliferation and nonneuronal cells in dorsal root ganglion cultures.
| ALogP | -1.2 |
|---|
| Pubchem Sid | 504750939 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/504750939 |
| Canonical Smiles | C1C(C(OC1N2C=C(C(=O)NC2=O)F)CO)O |
| IUPAC Name | 5-fluoro-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione |
| InChIKey | ODKNJVUHOIMIIZ-RRKCRQDMSA-N |
| INCHI | 1S/C9H11FN2O5/c10-4-2-12(9(16)11-8(4)15)7-1-5(14)6(3-13)17-7/h2,5-7,13-14H,1,3H2,(H,11,15,16)/t5-,6+,7+/m0/s1 |
| Isomeric SMILES | C1[C@@H]([C@H](O[C@H]1N2C=C(C(=O)NC2=O)F)CO)O |
| RTECS | YU7525000 |
| UN Number | 1760 |
| Packing Group | I |
| Molecular Weight | 246.19 |
| Reaxy-Rn | 24714617 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=24714617&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Nucleosides, nucleotides, and analogues |
| Class | Pyrimidine nucleosides |
| Subclass | Pyrimidine 2'-deoxyribonucleosides |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Pyrimidine 2'-deoxyribonucleosides |
| Alternative Parents | Pyrimidones Halopyrimidines Hydroxypyrimidines Aryl fluorides Hydropyrimidines Tetrahydrofurans Heteroaromatic compounds Secondary alcohols Oxacyclic compounds Azacyclic compounds Organic oxides Hydrocarbon derivatives Organofluorides Organonitrogen compounds Organopnictogen compounds Primary alcohols |
| Molecular Framework | Aromatic heteromonocyclic compounds |
| Substituents | Pyrimidine 2'-deoxyribonucleoside - Halopyrimidine - Hydroxypyrimidine - Pyrimidone - Aryl fluoride - Aryl halide - Hydropyrimidine - Pyrimidine - Heteroaromatic compound - Tetrahydrofuran - Secondary alcohol - Oxacycle - Organoheterocyclic compound - Azacycle - Alcohol - Hydrocarbon derivative - Primary alcohol - Organooxygen compound - Organonitrogen compound - Organofluoride - Organohalogen compound - Organic oxide - Organopnictogen compound - Organic oxygen compound - Organic nitrogen compound - Aromatic heteromonocyclic compound |
| Description | This compound belongs to the class of organic compounds known as pyrimidine 2'-deoxyribonucleosides. These are compounds consisting of a pyrimidine linked to a ribose which lacks a hydroxyl group at position 2. |
| External Descriptors | organofluorine compound - nucleoside analogue - pyrimidine 2'-deoxyribonucleoside |
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Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Jun 15, 2026 | F110732 | |
| Certificate of Analysis | Jan 17, 2026 | F110732 | |
| Certificate of Analysis | Jan 17, 2026 | F110732 | |
| Certificate of Analysis | Jan 17, 2026 | F110732 | |
| Certificate of Analysis | Jan 17, 2026 | F110732 | |
| Certificate of Analysis | Mar 30, 2024 | F110732 | |
| Certificate of Analysis | Mar 30, 2024 | F110732 | |
| Certificate of Analysis | Jul 21, 2023 | F110732 | |
| Certificate of Analysis | Jul 21, 2023 | F110732 | |
| Certificate of Analysis | Jul 21, 2023 | F110732 | |
| Certificate of Analysis | Jul 21, 2023 | F110732 | |
| Certificate of Analysis | Jul 21, 2023 | F110732 | |
| Certificate of Analysis | Jul 21, 2023 | F110732 | |
| Certificate of Analysis | Jul 21, 2023 | F110732 | |
| Certificate of Analysis | Jul 21, 2023 | F110732 | |
| Certificate of Analysis | Jul 21, 2023 | F110732 | |
| Certificate of Analysis | Jul 21, 2023 | F110732 | |
| Certificate of Analysis | Jul 21, 2023 | F110732 | |
| Certificate of Analysis | Jul 21, 2023 | F110732 | |
| Certificate of Analysis | Jul 21, 2023 | F110732 | |
| Certificate of Analysis | Jul 21, 2023 | F110732 | |
| Certificate of Analysis | Mar 17, 2023 | F110732 | |
| Certificate of Analysis | Aug 09, 2022 | F110732 | |
| Certificate of Analysis | Aug 09, 2022 | F110732 | |
| Certificate of Analysis | Aug 09, 2022 | F110732 |
| Solubility | Soluble in water, alcohol, isopropyl alcohol, methanol, aqueous buffers, acetone, dimethyl sulfoxide, and ethanol. Insoluble in ether, benzene and chloroform. |
|---|---|
| Sensitivity | heat sensitive |
| Specific Rotation[α] | 38 ° (C=1, H2O) |
| Melt Point(°C) | 148°C |
| Molecular Weight | 246.190 g/mol |
| XLogP3 | -1.200 |
| Hydrogen Bond Donor Count | 3 |
| Hydrogen Bond Acceptor Count | 6 |
| Rotatable Bond Count | 2 |
| Exact Mass | 246.065 Da |
| Monoisotopic Mass | 246.065 Da |
| Topological Polar Surface Area | 99.100 Ų |
| Heavy Atom Count | 17 |
| Formal Charge | 0 |
| Complexity | 386.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 3 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
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| 25. Kaijun Gu, Yu Tan, Sitong Li, Siyue Chen, Bing Fang, Kaili Lin, Yanmei Tang, Min Zhu. (2024) Sensory Nerve Regulation via H3K27 Demethylation Revealed in Akermanite Composite Microspheres Repairing Maxillofacial Bone Defect. Advanced Science, [PMID:38874525] [10.1002/advs.202400242] |
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