for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 24 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
| Pubchem Sid | 488187800 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488187800 |
| Isomeric SMILES | CCN1C(C2=C(C=CC(=C2)N)C3=C1C=C(C=C3)N)C4=CC=CC=C4 |
| PubChem CID | 128682 |
| Molecular Weight | 315.4 |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
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View spec sheet →Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 I2503698 | Certificate of Analysis | Jun 15, 2026 | R353922 |
| C2311484 | Certificate of Analysis | May 20, 2026 | R353922 |
| B2603554 | Certificate of Analysis | Dec 23, 2025 | R353922 |
| I2503697 | Certificate of Analysis | Jul 04, 2025 | R353922 |
| D2508631 | Certificate of Analysis | Mar 12, 2025 | R353922 |
| J2425746 | Certificate of Analysis | Sep 10, 2024 | R353922 |
| J2430116 | Certificate of Analysis | Sep 10, 2024 | R353922 |
| H2406654 | Certificate of Analysis | Jun 20, 2024 | R353922 |
| F2316746 | Certificate of Analysis | Mar 20, 2024 | R353922 |
| E2413573 | Certificate of Analysis | Mar 15, 2024 | R353922 |
| K2310231 | Certificate of Analysis | Oct 28, 2023 | R353922 |
| K2310230 | Certificate of Analysis | Oct 27, 2023 | R353922 |
| F2316737 | Certificate of Analysis | Jun 08, 2023 | R353922 |
| C2311480 | Certificate of Analysis | Jan 03, 2023 | R353922 |
| K2208505 | Certificate of Analysis | Nov 03, 2022 | R353922 |
| Sensitivity | light sensitive |
|---|---|
| Molecular Weight | 315.400 g/mol |
| XLogP3 | 3.900 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 3 |
| Rotatable Bond Count | 2 |
| Exact Mass | 315.174 Da |
| Monoisotopic Mass | 315.174 Da |
| Topological Polar Surface Area | 55.300 Ų |
| Heavy Atom Count | 24 |
| Formal Charge | 0 |
| Complexity | 419.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 1 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
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| 3. Xueliang Liu, Yingmin Zhou, Jin Liu, Hongjun Xia. (2020) The intrinsic enzyme mimetic activity of platinum oxide for biosensing of glucose. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, [PMID:33310614] [10.1016/j.saa.2020.119280] |
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