Furo[2,3-d]pyrimidines

Description:

Aromatic heteropolycyclic compounds containing a furo[2,3-d]pyrimidine ring system, which is a furopyrimidine isomer having the on ring oxygen atom, and 2 nitrogen atoms at the 1-, 5-, and 7-positions, respectively.

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  1. Cf 1743
    CAS: 319425-66-6 PubChem CID: 493485 Formula: C22H26N2O5 Molecular Weight: 398.45
    Out of Stock Item #: C1026702
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    Technical Identifiers
    IUPAC Name
    3-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-6-(4-pentylphenyl)furo[2,3-d]pyrimidin-2-one
    SMILES
    CCCCCC1=CC=C(C=C1)C2=CC3=CN(C(=O)N=C3O2)C4CC(C(O4)CO)O
    InChIKey
    MFGSDSRTGUVZQG-DFQSSKMNSA-N
    InChI
    1S/C22H26N2O5/c1-2-3-4-5-14-6-8-15(9-7-14)18-10-16-12-24(22(27)23-21(16)29-18)20-11-17(26)19(13-25)28-20/h6-10,12,17,19-20,25-26H,2-5,11,13H2,1H3/t17-show more
  2. TIE-2/VEGFR-2 kinase-IN-1
    CAS: 453590-24-4 PubChem CID: 5329802 Formula: C13H11N3O2 Molecular Weight: 241.25
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    Out of Stock Item #: T646632
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    IUPAC Name
    6-(4-methoxyphenyl)furo[2,3-d]pyrimidin-4-amine
    SMILES
    COC1=CC=C(C=C1)C2=CC3=C(N=CN=C3O2)N
    InChIKey
    DIJLFIHLUYAZCI-UHFFFAOYSA-N
    InChI
    1S/C13H11N3O2/c1-17-9-4-2-8(3-5-9)11-6-10-12(14)15-7-16-13(10)18-11/h2-7H,1H3,(H2,14,15,16)
    Synonyms
    AB01092273-01 | DTXSID70416199 | BDBM5804 | MS-23414 | Oprea1_097150 | 6-(4-methoxyphenyl)furo[2,3-d]pyrimidin-4-amin...
  3. 4,6-Dimethylfuro[2,3-d]pyrimidin-2-amine
    CAS: 22727-43-1 Formula: C8H9N3O Molecular Weight: 163.18
    Reagent Grade ? General reagent-grade purity suitable for most laboratory work. Use as a dependable default when no specific higher grade is required.
    Out of Stock Item #: D478855
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    Technical Identifiers
    IUPAC Name
    4,6-dimethylfuro[2,3-d]pyrimidin-2-amine
    SMILES
    CC1=CC2=C(N=C(N=C2O1)N)C
    InChIKey
    MSEVJFYMGKQFNO-UHFFFAOYSA-N
    InChI
    1S/C8H9N3O/c1-4-3-6-5(2)10-8(9)11-7(6)12-4/h3H,1-2H3,(H2,9,10,11)
    Synonyms
    6-Amino-2,4-dimethyl-5,7-diazabenzofuran | 4,6-Dimethylfuro[2,3-d]pyrimidin-2-amine | Oprea1_258760 | Furo[2,3-d]pyri...
  4. WAY-647361
    CAS: 852399-94-1 PubChem CID: 4962030 Formula: C8H6N2O4 Molecular Weight: 194.14424
    In Stock Item #: W418252
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    Technical Identifiers
    IUPAC Name
    6-methyl-4-oxo-3H-furo[2,3-d]pyrimidine-5-carboxylic acid
    SMILES
    CC1=C(C2=C(O1)N=CNC2=O)C(=O)O
    InChIKey
    FUUXILGTYMNJST-UHFFFAOYSA-N
    InChI
    1S/C8H6N2O4/c1-3-4(8(12)13)5-6(11)9-2-10-7(5)14-3/h2H,1H3,(H,12,13)(H,9,10,11)
    Synonyms
    AKOS000117847 | AKOS027247963 | WAY-647361 | SCHEMBL13958247 | 6-methyl-4-oxo-3,4-dihydrofuro[2,3-d]pyrimidine-5-carb...
  5. WAY-647361
    CAS: 852399-94-1 EC Number: 843-300-4 PubChem CID: 4962030 Formula: C8H6N2O4 Molecular Weight: 194.14424
    10mM in DMSO
    In Stock Item #: W426282
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    Technical Identifiers
    IUPAC Name
    6-methyl-4-oxo-3H-furo[2,3-d]pyrimidine-5-carboxylic acid
    SMILES
    CC1=C(C2=C(O1)N=CNC2=O)C(=O)O
    InChIKey
    FUUXILGTYMNJST-UHFFFAOYSA-N
    InChI
    1S/C8H6N2O4/c1-3-4(8(12)13)5-6(11)9-2-10-7(5)14-3/h2H,1H3,(H,12,13)(H,9,10,11)
    Synonyms
    AKOS000117847 | AKOS027247963 | WAY-647361 | SCHEMBL13958247 | 6-methyl-4-oxo-3,4-dihydrofuro[2,3-d]pyrimidine-5-carb...
  6. 4-chlorofuro[2,3-d]pyrimidine
    CAS: 918340-51-9 Formula: C6H3ClN2O Molecular Weight: 154.55
    Out of Stock Item #: C178220
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    Technical Identifiers
    IUPAC Name
    4-chlorofuro[2,3-d]pyrimidine
    SMILES
    C1=COC2=C1C(=NC=N2)Cl
    InChIKey
    RXNNSCCBHMRHIX-UHFFFAOYSA-N
    InChI
    1S/C6H3ClN2O/c7-5-4-1-2-10-6(4)9-3-8-5/h1-3H
    Synonyms
    A844076 | AKOS006327886 | FT-0646724 | MFCD09834941 | Furo[2,3-d]pyrimidine,4-chloro- | RXNNSCCBHMRHIX-UHFFFAOYSA-N |...
  7. furo[2,3-d]pyrimidin-4-amine
    Out of Stock Item #: F175300
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    Technical Identifiers
    IUPAC Name
    furo[2,3-d]pyrimidin-4-amine
    SMILES
    C1=COC2=NC=NC(=C21)N
    InChIKey
    JPIPZNJBXFDXHH-UHFFFAOYSA-N
    InChI
    1S/C6H5N3O/c7-5-4-1-2-10-6(4)9-3-8-5/h1-3H,(H2,7,8,9)
    Synonyms
    furo[2,3-d]pyrimidin-4-amine (9ci) | AKOS006328321 | AMY6648 | DTXSID20432485 | SY323983 | MFCD09834959 | AS-41608 | ...
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