Letolizumab (anti-TNFSF5) - Primary antibody, specific to CD40LG, VHH-Fc

CAS: 1450981-87-9 Cat. No.: Ab182769
Disponible para pedir
GRADE & PURITY Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. ≥95%(SDS-PAGE&SEC-HPLC) See COA
Application
Animal Model, ELISA, Flow Cytometry, Functional Assay
Host species
Human
Reactive species
Human
Isotype
VHH-Fc
Conjugation
Unconjugated
 ·  off list, applied to all prices below.
Size
Estado
Price
Qty
100μg
Ab182769-100μg
5
99,90US$
1mg
Ab182769-1mg
2
495,90US$
5mg
Ab182769-5mg
1
1.293,90US$
10mg
Ab182769-10mg
1-2 wks(?)
Item is derived from our semi-finished stock and is processed in 1-2 weeks.
2.071,90US$
Enter a quantity for the sizes you want to add.
🧪

Why this grade

Carrier Free, Recombinant, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA Animal Free,Azide Free,Carrier Free,Low Endotoxin,Recombinant,Validated for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -80°C,Avoid repeated freezing and thawing Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Descripción general

Letolizumab (anti-TNFSF5) is a monoclonal antibody targeting CD40L, which is produced to express mutant IgG1 lacking effector function, including Fc binding and complement fixation. Letolizumab (anti-TNFSF5) reduces rejection, thromboembolism and prolongs the survival time.
Purity
≥95% (SDS-PAGE&SEC)
Endotoxin Level
≤1.0EU/mg

Specifications

Product Name
Letolizumab (anti-TNFSF5) - Primary antibody, specific to CD40LG, VHH-Fc
Sinónimos
CD154 antibody | CD40 antigen ligand antibody | CD40L antibody | CD40LG antibody | Gp39 antibody | HIGM1 antibody | Hyper IgM syndrome antibody | IGM antibody | IMD3 antibody | Ly62 antibody | T B cell activating molecule antibody | TBAM antibody | TNF re
Especificaciones y pureza
Carrier Free, Recombinant, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Especies hospedadoras
Human
Especificidad
CD40LG
Conjugación
Unconjugated
Grado
Animal Free, Azide Free, Carrier Free, Low Endotoxin, Recombinant, Validated
Tipo de acción
INHIBITOR
Isotipo
VHH-Fc
SDS-PAGE
26.3 kDa (Light Chain) & 53.0 kDa (Heavy Chain), under reducing conditions; 205.5 kDa, under non-reducing conditions.
Método de purificación
Protein A purified
Concentración
See COA
CAS
1450981-87-9
Almacenamiento y envío
Forma
Liquid
Condiciones de almacenamiento de almacenamiento
Store at -80°C,Avoid repeated freezing and thawing
Enviado en
Dry ice packs + Cold packs
Estabilidad y almacenamiento
Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
Imágenes

Letolizumab (anti-TNFSF5) (Ab182769) - Flow
Flow Cytometry analysis of pLVX-puro-SYMX10-TNFSF5(CD40L)-FL-HEK293 cells labelling TNFSF5 with Letolizumab (anti-TNFSF5) (Ab182769), and negative control protein respectively, washed and then followed by PE and analyzed with the FACS EC ₅₀  is 0.05 nM.

Letolizumab (anti-TNFSF5) (Ab182769) - ELISA
Immobilized Recombinant Human CD40 Ligand protein (rp169583) at 1.0 μg/mL can bind Letolizumab (anti-TNFSF5) (Ab182769) with the EC ₅₀   of 11.26 ng/mL.

Letolizumab (anti-TNFSF5) (Ab182769) - SEC
The purity of Letolizumab (anti-TNFSF5) (Ab182769) is more than 95% verified by HPLC.

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Objetivos asociados (humanos)
CD40LG Tbio CD40 ligand (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
Mecanismos de acción
Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot NumberCertificate TypeFechaArticulo
ZJ24F0708868Certificate of AnalysisMay 21, 2026 Ab182769
ZJ24F0708869Certificate of AnalysisMay 21, 2026 Ab182769
ZJ24F0708870Certificate of AnalysisMay 21, 2026 Ab182769
Calculadoras de soluciones
Reseñas

Reseñas de cliente

Need help choosing the grade?

Our grade selection guide covers purity, stabilizer status, and application suitability for all variants in our catalog.

View Animal Free grade guide → View Carrier Free grade guide → View Recombinant grade guide → View Validated grade guide → View Low Endotoxin grade guide → View Azide Free grade guide →

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