ExactAb™, Validated, Carrier Free, 2.0 mg/mL Carrier Free,ExactAb™,Validated for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -20°C,Avoid repeated freezing and thawing Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Rabbit anti Human PP2A-alpha Antibody, Polyclonal, could be used for WB, IHC and so on.
Application:
WB: 1/1000
IHC: 1/100-1/500
Protein Function:
PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGOL2 to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I (By similarity). Can dephosphorylate SV40 large T antigen and p53/TP53. Dephosphorylates SV40 large T antigen, preferentially on serine residues 120, 123, 677, and perhaps 679. The C subunit was most active, followed by the AC form, which was more active than the ABC form, and activity of all three forms was strongly stimulated by manganese, and to a lesser extent by magnesium. Dephosphorylation by the AC form, but not C or ABC form is inhibited by small T antigen.
PP2A-alpha Antibody (Ab122718) - Western Blot
All lanes: PP2A-alpha Antibody (Ab122718) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 36 kDa
Observed band size: 35 kDa
Exposure time: 48.1 s
PP2A-alpha Antibody (Ab122718) - IHC
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of PP2A-alpha Antibody (Ab122718) for immunohistochemistry; clinical relevance has not been evaluated. HC = hepatocarcinoma.
| Aplicación | Dilution info |
|---|---|
| IHC | 1/100-1/500 |
| WB |
1/1000
|
| IF/ICC | 1/200 |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Fecha | Articulo |
|---|---|---|---|
 ZJ24F0303423 | Certificate of Analysis | Mar 20, 2024 | Ab122718 |
| ZJ24F0303424 | Certificate of Analysis | Mar 20, 2024 | Ab122718 |
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View Carrier Free grade guide → View Validated grade guide → View ExactAb™ grade guide →
