Recombinant CPEB1 Antibody - Primary antibody, specific to CPEB1, Rabbit IgG

Cat. No.: Ab097517

GRADE & PURITY Recombinant, Validated, ExactAb™, See COA

Application

WB

Host species

Rabbit

Reactive species

Human

Isotype

Rabbit IgG

Conjugation

Unconjugated

Descripción general

Purity

Rabbit anti Human CPEB1 Antibody, Recombinant, could be used for WB and so on.
Application:
WB: 1/500-1/2000
Protein Function
Sequence-specific RNA-binding protein that regulates mRNA cytoplasmic polyadenylation and translation initiation during oocyte maturation, early development and at postsynapse sites of neurons. Binds to the cytoplasmic polyadenylation element (CPE), an uridine-rich sequence element (consensus sequence 5'-UUUUUAU-3') within the mRNA 3'-UTR. In absence of phosphorylation and in association with TACC3 is also involved as a repressor of translation of CPE-containing mRNA; a repression that is relieved by phosphorylation or degradation (By similarity). Involved in the transport of CPE-containing mRNA to dendrites; those mRNAs may be transported to dendrites in a translationally dormant form and translationally activated at synapses (By similarity). Its interaction with APLP1 promotes local CPE-containing mRNA polyadenylation and translation activation (By similarity). Induces the assembly of stress granules in the absence of stress.

Specifications

Product Name

Recombinant CPEB1 Antibody - Primary antibody, specific to CPEB1, Rabbit IgG

Sinónimos

CPE-binding protein 1 | CPE-BP1 | CPEB 1 | CPEB | CPEB1 | CPEB1 protein | CPEB1_HUMAN | Cytoplasmic polyadenylation binding protein 1 | Cytoplasmic polyadenylation element binding protein | Cytoplasmic polyadenylation element binding protein 1 | Cytoplasm

Especificaciones y pureza

Recombinant, ExactAb™, Validated, See COA

Especies hospedadoras

Rabbit

Especificidad

CPEB1

Inmunógeno

A synthesized peptide derived from human CPEB1 (AA 265-325)

Control positivo

WB: A549, K562, HeLa and SK-N-SH cell lysates.

Conjugación

Unconjugated

Grado

ExactAb™, Recombinant, Validated

Isotipo

Rabbit IgG

Tipo de cadena ligera

kappa

SDS-PAGE

150 kDa

Método de purificación

Protein A purified

Concentración

See COA

Almacenamiento y envío

Forma

Liquid

Condiciones de almacenamiento de almacenamiento

Store at -20°C,Avoid repeated freezing and thawing

Enviado en

Ice chest + Ice pads

Estabilidad y almacenamiento

Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Imágenes

Western Blot: Recombinant CPEB1 Antibody (Ab097517)

Recombinant CPEB1 Antibody (Ab097517) - Western Blot
All lanes: Recombinant CPEB1 Antibody (Ab097517) at 1/2000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution

Predicted band size: 63 kDa
Observed band size: 68 kDa
Exposure time: 26.0 s

Aplicación

• Aplicación: Dilution info
• WB:

  1/500-1/2000;

Objetivos asociados (humanos)

CPEB1 Tbio Cytoplasmic polyadenylation element-binding protein 1 (0 Activities)

Discover Target: CPEB1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)