GRADE & PURITYRecombinant?Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin.Validated?Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated.ExactAb™?ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications.0.5 mg/mL
ExactAb™, Validated, Recombinant, 0.5 mg/mL ExactAb™,Recombinant,Validated for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
🌡
Storage & shipping
Store at -20°C,Avoid repeated freezing and thawing Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
📋
Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
📚
Literature proof
Cited in 1 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Descripción general
Rabbit anti Human HMGCR Antibody, Recombinant, could be used for WB and so on.
Specifications
Product Name
Recombinant HMGCR Antibody - Primary antibody, specific to HMGCR, Rabbit IgG
Sinónimos
EC 1.1.1.34 | HMG-CoA reductase | 3 hydroxy 3 methylglutaryl CoA reductase | 3 hydroxy 3 methylglutaryl Coenzyme A reductase | 3 hydroxymethylglutaryl CoA reductase | 3-hydroxy-3-methylglutaryl CoA reductase (NADPH) | 3-hydroxy-3-methylglutaryl-coenzyme A
Especificaciones y pureza
ExactAb™, Validated, Recombinant, 0.5 mg/mL
Mecanismos bioquímicos y fisiológicos
This transmembrane glycoprotein is involved in the control of cholesterol biosynthesis. It is the rate-limiting enzyme of sterol biosynthesis.
Especies hospedadoras
Rabbit
Especificidad
HMGCR
Inmunógeno
A synthetic peptide derived from human HMGCR (AA 448-462)
Control positivo
WB: K562, HeLa, MCF7, NIH/3T3 and C6 cell lysates.
Conjugación
Unconjugated
Grado
ExactAb™, Recombinant, Validated
Isotipo
Rabbit IgG
Tipo de cadena ligera
kappa
SDS-PAGE
150 kDa
Método de purificación
Protein A purified
Concentración
0.5 mg/mL
Almacenamiento y envío
Forma
Liquid
Condiciones de almacenamiento de almacenamiento
Store at -20°C,Avoid repeated freezing and thawing
Enviado en
Ice chest + Ice pads
Estabilidad y almacenamiento
Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
Imágenes
Recombinant HMGCR Antibody (Ab108327) - Western Blot All lanes: Recombinant HMGCR Antibody (Ab108327) at 1/1000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 97 kDa Observed band size: 102 kDa Exposure time: 35.0 s
Recombinant HMGCR Antibody (Ab108327) - Western Blot All lanes: Recombinant HMGCR Antibody (Ab108327) at 1/1000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 97 kDa Observed band size: 102 kDa Exposure time: 20.0 s
Aplicación
Aplicación
Dilution info
WB
1/1000
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
1.Mei-Xin Li, Yiqing Yang, Qiuye Zhao, Yue Wu, Lei Song, Haiyan Yang, Ming He, Hongying Gao, Bao-Liang Song, Jie Luo, Yu Rao. (2020) Degradation versus Inhibition: Development of Proteolysis-Targeting Chimeras for Overcoming Statin-Induced Compensatory Upregulation of 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase. JOURNAL OF MEDICINAL CHEMISTRY, [PMID:32321253][10.1021/acs.jmedchem.0c00339]
Calculadoras de soluciones
Molarity Calculator
Determine the necessary mass, volume, or concentration for preparing a solution.
Dilution Calculator
Determine the dilution needed to prepare a stock solution.
Reconstitution Calculator
Reseñas
Reseñas de cliente
Need help choosing the grade?
Our grade selection guide covers purity, stabilizer status, and application suitability for all variants in our catalog.
We use cookies to ensure the website functions properly and, where permitted, to improve your experience. You can manage your preferences at any time in Settings. Learn more in our Cookie Policy.
Shall we send you a message when we have discounts available?
Remind me later
Thank you! Please check your email inbox to confirm.
Products are supplied to verified businesses, institutions, and qualified professionals for research and development use only. Not for use in humans, animals, diagnosis, or therapy.
ZJ24F0303883
