Lipopolysaccharide(LPS) - Derived from Escherichia coli 055: B5, purified by trichloroacetic acid extraction , CAS No.93572-42-0

CAS: 93572-42-0 Cat. No.: L386714 EC Number: 297-473-0

GRADE & PURITY Derived from Escherichia coli 055: B5, purified by trichloroacetic acid extraction

Synonyms

LPS

Storage

Store at 2-8°C

Shipped In

Wet ice

Overview

Lipopolysaccharide,|E. coli|O55:B5 is a component of the cell wall of the O55:B5 serotype of the Gram-negative bacteria,|Escherichia coli|. Lipopolysaccharides (LPS) are made up of a hydrophobic lipid, a hydrophilic core polysaccharide chain and a hydrophilic O-antigenic polysaccharide side chain. LPS molecules contribute to the outer integrity of the cell membrane, protect the cell against bile salts and lipophilic antibiotics, and act as endotoxins in animals. LPS induces a strong immune response by binding to the CD14/TLR4/MD2 receptor complex, which promotes the secretion of pro-inflammatory cytokines. LPS is also an exogenous pyrogen. LPS O55:B5 has been derived from a serotype of|E. coli|O55:B5, which is part of a subdivision based on the O antigen component of LPS. Lipopolysaccharide, E. coli O55:B5 is a form of lipopolysaccharide (LPS) extracted from wild-type S-form E. coli serotype O55:B5. Lipopolysaccharide, E. coli O55:B5 is commonly used to activate toll-like receptor 4 (TLR4) on leukocytes, eliciting inflammatory signaling in isolated cells and in vivo.1,2,3,4 Lipopolysaccharide, E. coli O55:B5 includes three regions, the O-antigenic polysaccharide chain, the core oligosaccharide, and lipid A. Lipopolysaccharide, E. coli O55:B5 stimulates the activity of inducible nitric oxide synthase. Lipopolysaccharide, E. coli O55:B5 induces apoptosis in mouse thymus and swine lymphocytes. Lipopolysaccharide, E. coli O55:B5 is also known as LPS. Lipopolysaccharide, E. coli O55:B5is a component of the cell wall of Gram-negative bacteria and Specific activator of Toll-like receptor (TLR) 4.

Usage:

The product is soluble in water (5 mg/ml) or cell culture medium (1 mg/ml) yielding a hazy, faint yellow solution. A more concentrated, though still hazy, solution (20 mg/ml) has been achieved in aqueous saline after vortexing and warming to 70-80 oC. Lipopolysaccharides are molecules that form micelles in every solvent. Hazy solutions are observed in water and phosphate buffered saline. Organic solvents do not give clearer solutions. Methanol yields a turbid suspension with floaters, while water yields a homogeneously hazy solution.

Specifications

Synonyms

LPS

Specifications & Purity

Derived from Escherichia coli 055: B5, purified by trichloroacetic acid extraction

Biochemical and Physiological Mechanisms

Physiol Actions：Lipopolysaccharides (LPS) are localized in the outer layer of the membrane and are, in noncapsulated strains, exposed on the cell surface. They contribute to the integrity of the outer membrane, and protect the cell against the action of b

Storage

Store at 2-8°C

Shipped In

Wet ice

This product requires cold chain shipping. Ground and other economy services are not available.

Chemical and Physical Properties

• Solubility: Soluble in water (5 mg/ml).

References

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66. Qin Wang, Liming He, Donghao Fan, Wenlang Liang, Jiyu Fang.  (2020)  Improving the anti-inflammatory efficacy of dexamethasone in the treatment of rheumatoid arthritis with polymerized stealth liposomes as a delivery vehicle.  Journal of Materials Chemistry B,  8  (9): (1841-1851).  [PMID:32016224] [10.1039/C9TB02538C]

67. Minglei Chen, Kambere Amerigos Daddy J.C., Zhigui Su, Nida El Islem Guissi, Yanyu Xiao, Li Zong, Qineng Ping.  (2019)  Folate Receptor-Targeting and Reactive Oxygen Species-Responsive Liposomal Formulation of Methotrexate for Treatment of Rheumatoid Arthritis.  Pharmaceutics,  11  (11): (582).  [PMID:31698794] [10.3390/pharmaceutics11110582]

68. Ming-Quan Guo.  (2019)  Antioxidant and Anti-Inflammatory Activities of the Crude Extracts of Moringa oleifera from Kenya and Their Correlations with Flavonoids.  Antioxidants,  8  (8): (296).  [PMID:31404978] [10.3390/antiox8080296]

69. Xiao-Yan Zhu, Hao Wu, Xiao-Feng Guo, Hong Wang.  (2019)  Novel BODIPY-based fluorescent probes with large Stokes shift for imaging hydrogen sulfide.  DYES AND PIGMENTS,      [PMID:] [10.1016/j.dyepig.2019.02.050]

70. Zhi Na YIN, Wen Jia WU, Chong Zhen SUN, Hui Fan LIU, Wen Bo CHEN, Qi Ping ZHAN, Zhuo Gui LEI, Xuan XIN, Juan Juan MA, Kun YAO, Tian MIN, Meng Meng ZHANG, Hui WU.  (2019)  Antioxidant and Anti-inflammatory Capacity of Ferulic Acid Released from Wheat Bran by Solid-state Fermentation of Aspergillus niger.  BIOMEDICAL AND ENVIRONMENTAL SCIENCES,      [PMID:30696535] [10.3967/bes2019.002]

71. Han Wang, Yongkuan Li, Man Yang, Peng Wang, Yueqing Gu.  (2019)  FRET-Based Upconversion Nanoprobe Sensitized by Nd3+ for the Ratiometric Detection of Hydrogen Peroxide in Vivo.  ACS Applied Materials & Interfaces,      [PMID:30673225] [10.1021/acsami.8b21549]

72. Xiaolin Wang, Teng Ma, Xiaojian Wan, Yan Meng, Zhenzhen Zhao, Jinjun Bian, Rui Bao, Xiaoming Deng, Tao Yang.  (2018)  IGFBP7 regulates sepsis-induced acute kidney injury through ERK1/2 signaling.  JOURNAL OF CELLULAR BIOCHEMISTRY,  120  (5): (7602-7611).  [PMID:30450602] [10.1002/jcb.28035]

73. Cuicui Duan, Yujuan Zhao, Cheng Huang, Zijian Zhao, Lei Gao, Chunhua Niu, Chao Wang, Xiaoxiao Liu, Chuan Zhang, Shengyu Li.  (2018)  Hepatoprotective effects of Lactobacillus plantarum C88 on LPS/D-GalN–induced acute liver injury in mice.  Journal of Functional Foods,      [PMID:] [10.1016/j.jff.2018.02.005]

74. Yunfei Ji, Ruijun Wang, Ying Peng, Chongsheng Peng, Xiaobo Li.  (2017)  Purification, Preliminary Characterization, and Immunological Activity of Polysaccharides from Crude Drugs of Sijunzi Formula.  Evidence-based Complementary and Alternative Medicine,      [PMID:28804502] [10.1155/2017/2170258]

75. Wanyu Li, Qingbang Ye, Zhonghao Jiang, Dong Xia, Zhuo Yan, Dan Wang, Yanan Chen, Tianshou Cao, Jilong Wang, Chihao Lin, Huiling Yang, Junjie Deng, Jiantao Lin.  (2024)  A cross-linked macropore hydrogel based on M1 macrophage lysate and alginate regulates tumor-associated macrophages for the treatment of melanoma.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:38705331] [10.1016/j.ijbiomac.2024.132089]

76. Xiaoliang Qi, Yizuo Shi, Chaofan Zhang, Erya Cai, XinXin Ge, Yajing Xiang, Ying Li, Bairui Zeng, Jianliang Shen.  (2024)  A Hybrid Hydrogel with Intrinsic Immunomodulatory Functionality for Treating Multidrug-Resistant Pseudomonas aeruginosa Infected Diabetic Foot Ulcers.  ACS Materials Letters,      [PMID:] [10.1021/acsmaterialslett.4c00392]

77. Zhouyu Zhang, Zi-Jin Wei, Mengjie Sun, Zichao Yan, Chang Yin, Wei Wang, Zhi Yuan.  (2024)  A hypochlorite-activatable persistent luminescence nanoprobe for assisted tumor resection.  Materials Chemistry Frontiers,      [PMID:] [10.1039/D3QM01308A]

78. Yanni Luo, Caiying Li, Fanggui Ye, Jianniao Tian, Xuecai Tan, Shengqiang Hu, Shulin Zhao.  (2024)  A Macrophage Membrane-Coated Cu–WO3–x-Hydro820 Nanoreactor for Treatment and Photoacoustic/Fluorescence Dual-Mode Imaging of Inflamed Liver Tissue.  ANALYTICAL CHEMISTRY,      [PMID:38613481] [10.1021/acs.analchem.4c00889]

79. Shulei Qi, Lina Guo, Jinxin Liang, Kaixuan Wang, Qinghong Liao, Siyu He, Weiping Lyu, Zimeng Cheng, Jiayi Wang, Xiaojia Luo, Xiaomei Yan, Ziyao Lu, Xiaohan Wang, Ziming Wang, Xuehong Chen, Qi Li.  (2024)  A new strategy for the treatment of Parkinson’s disease: Discovery and bio-evaluation of the first central-targeting tyrosinase inhibitor.  BIOORGANIC CHEMISTRY,      [PMID:38986418] [10.1016/j.bioorg.2024.107612]

80. Chengchen Pang, Bei Yuan, Keyun Ren, Haitao Xu, Kunying Nie, Chunlei Yu, Zhanli Liu, Yanyan Zhang, Sibel A. Ozkan, Qingqing Yang.  (2024)  Activates B lymphocytes and enhanced immune response: A promising adjuvant based on PLGA nanoparticle to improve the sensitivity of ZEN monoclonal antibody.  TALANTA,      [PMID:38599116] [10.1016/j.talanta.2024.126005]

81. Lei Li, Haoze Li, Junrong Wang, Yulin Xie, Minghong Gao, Zhongjun Yang, Chunxia Li.  (2024)  An Asymmetric Bacterial Cellulose Membrane Incorporating CuPt Nanozymes and Curcumin for Accelerating Wound Healing.  ACS Applied Materials & Interfaces,      [PMID:39586586] [10.1021/acsami.4c10720]

82. Yu Lan, Haixia Zhang, Ruichen Xie, Kecheng Li, Feiran Xie, Peihong Xiao, Li Jiang.  (2024)  An endoplasmic reticulum-targeted NIR fluorescent nanoprobe for early diagnosis of glaucoma in vivo.  SENSORS AND ACTUATORS B-CHEMICAL,      [PMID:] [10.1016/j.snb.2024.135441]

83. Yibiao Wang, Xiaomei Fu, Yang Zhu, Mingjing Lin, Renduan Cai, Yang Zhu, Tiantian Wu.  (2024)  An intratumor bacteria-targeted DNA nanocarrier for multifaceted tumor microenvironment intervention.  Materials Today Bio,      [PMID:39070095] [10.1016/j.mtbio.2024.101144]

84. Zhen He, Xiangyun Tan, Ming Yuan, Liang Chen, Yan Meng, Qi Wang, Junjie Hu, Zhenpeng Qiu, Yuan Yang.  (2025)  Anethole trithione mitigates LPS/D-Gal-induced acute liver injury by suppressing ROS production and NF-κB activity.  INTERNATIONAL IMMUNOPHARMACOLOGY,      [PMID:40054324] [10.1016/j.intimp.2025.114371]

85. Yueqi Hu, Li Zhou, Jian Yang, Ruibin Bai, Eric Marchioni, Minjie Zhao, Li Zhou.  (2024)  Anti-inflammatory mechanism of Houttuynia cordata polysaccharides against ulcerative colitis based on multi-omics conjoint analysis.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:39521219] [10.1016/j.ijbiomac.2024.137311]

86. Huang Lanli, Yao Yi, Ruan Zhuren, Zhang Shengqing, Feng Xianjing, Lu Chun, Zhao Jinmin, Yin Feiying, Cao Cunwei, Zheng Li.  (2024)  Baicalin nanodelivery system based on functionalized metal-organic framework for targeted therapy of osteoarthritis by modulating macrophage polarization.  JOURNAL OF NANOBIOTECHNOLOGY,  22  (1): (1-19).  [PMID:38724958] [10.1186/s12951-024-02494-5]

87. Yuxin Zhang, Lixuan Yang, Yonghui Gan, Chenchen Zhao, Chao Zhou, Jian Chen, Yanping Yin, Shengnan Xia, Haiyan Yang, Xinyu Bao, Meijuan Zhang, Yun Xu, Jingwei Li.  (2024)  Benzydamine attenuates microglia-mediated neuroinflammation and ischemic brain injury by targeting cathepsin s.  INTERNATIONAL IMMUNOPHARMACOLOGY,      [PMID:39700961] [10.1016/j.intimp.2024.113824]

88. Qiao Chen, Xu Yang, Yao Yu, Xinmei Duan, Rongrong Ni, Guojing Song, Li Zhu, Yuan Zhong, Kai Qu, Xian Qin, Kun Zhang, Yang Luo, Wei Wu.  (2025)  Biomimetic Cerium-Assisted Supra-Carbon Dots Assembly for Reactive Oxygen Species-Activated Atherosclerosis Theranostic.  Small,      [PMID:39777854] [10.1002/smll.202408980]

89. Kun Xu, Yanan Zou, Chuanchuan Lin, Liangshuai Zhang, Meijun Tan, Meng Li, Jing Wu, Xuan Li, Ye He, Peng Liu, Ke Li, Kaiyong Cai.  (2024)  Cascade catalysis nanozyme for interfacial functionalization in combating implant infections associated with diabetes via sonodynamic therapy and adaptive immune activation.  BIOMATERIALS,      [PMID:38850718] [10.1016/j.biomaterials.2024.122649]

90. Jingwei Wu, Zhihui Li, Zhuoting Zhang, Jian Zhang, Hangyu Hu, Hanglian Lan, Weilian Hong, Zhennai Yang.  (2025)  Characterization of a postbiotic exopolysaccharide produced by Lacticaseibacillus paracasei ET-22 with antioxidant and anti-inflammatory efficacy.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:40037455] [10.1016/j.ijbiomac.2025.141608]

91. Sun Yujiao, Li Baobao, Xue Yuanye, Wang Jiankang, Miao Bingbing, Liu Yang, Li Yanjun, Cao Yungang, Chang Dawei.  (2024)  Comparison of immunomodulatory activity of polysaccharides and soluble dietary fibers and adsorption capacities of insoluble dietary fibers extracted from Lentinus edodes stipes.  Food Production Processing and Nutrition,  6  (1): (1-17).  [PMID:] [10.1186/s43014-024-00240-w]

92. Xu Wei, Chang Wan, Xu Peng, Yihao Luo, Mengyue Hu, Can Cheng, Shaoxiong Feng, Xixun Yu.  (2024)  Copper-based carbon dots modified hydrogel with osteoimmunomodulatory and osteogenesis for bone regeneration.  Journal of Materials Chemistry B,      [PMID:38771222] [10.1039/D4TB00526K]

93. Qi Tao, Hang Yao, Feifei Wang, Zehao Gu, Xiaofei Yang, Yuchi Zhao, Huan Pang, Dong-An Wang, Hui Chong.  (2024)  Curcumin-Encapsulated Co-ZIF-8 for Ulcerative Colitis Therapy: ROS Scavenging and Macrophage Modulation Effects.  ACS Omega,      [PMID:39035970] [10.1021/acsomega.4c02446]

94. Yue Xiyue, Lai Lunmeng, Wang Ruina, Tan Lulu, Wang Yanping, Xie Qing, Li Yunsen.  (2024)  DGA ameliorates severe acute pancreatitis through modulating macrophage pyroptosis.  INFLAMMATION RESEARCH,      [PMID:39231819] [10.1007/s00011-024-01931-3]

95. Zi-Qiang Feng, Jing Ding, Min-Zhen Zhu, Wei-Song Xie, Rui-Chen Liu, Si-Si Liu, Si-Meng Liu, Ming-Jia Yu, Xin-Hong Zhu, Jian-Hua Liang.  (2024)  Discovery of a novel lead characterized by a stilbene-extended scaffold against sepsis as soluble epoxide hydrolase inhibitors.  EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY,      [PMID:38215588] [10.1016/j.ejmech.2023.116113]

96. Shuyan Liu, Shunqing Zhou, Bo Wang, Zanhui Jia.  (2024)  Effects of curcumin nanoparticles on the proliferation and migration of human ovarian cancer cells assessed through the NF-κB/PRL-3 signaling pathway.  INTERNATIONAL IMMUNOPHARMACOLOGY,      [PMID:39168025] [10.1016/j.intimp.2024.112964]

97. Zhiwei Zeng, Yuhan Meng, Zunxian Yang, Yuliang Ye, Qiuxiang Lin, Zongyi Meng, Hongyi Hong, Songwei Ye, Zhiming Cheng, Qianting Lan, Jiaxiang Wang, Ye Chen, Hui Zhang, Yuting Bai, Xudong Jiang, Benfang Liu, Jiajie Hong, Tailiang Guo, Fushan Li, Yongyi Chen, Zhenzhen Weng.  (2024)  Efficient CsPbBr3 Perovskite Light-Emitting Diodes via Novel Multi-Step Ligand Exchange Strategy Based on Zwitterionic Molecules.  ACS Applied Materials & Interfaces,      [PMID:38364294] [10.1021/acsami.3c17324]

98. Xinqi Xu, Fahui Xu, Jingjing Chen, Shumin Wang, Xialian Wang, Bingmei Su, Lian Xu, Juan Lin.  (2025)  Engineering of a (R)-selective Baeyer-Villiger monooxygenase to minimize overoxidation activity for asymmetric synthesis of active pharmaceutical prazoles.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:39793827] [10.1016/j.ijbiomac.2025.139561]

99. Qianqian Zheng, Gui Mei, Ping Cheng, Yahong Li, Qingfeng Zhang, Mingwei Ye.  (2025)  Exploration of ω-9MUFAs: mitigating effect on lipopolysaccharide-induced acute lung injury..  EUROPEAN JOURNAL OF PHARMACOLOGY,      [PMID:40058759] [10.1016/j.ejphar.2025.177396]

100. Junpeng Lv, Di Wu, Yingming Ma, Xiyao Zhang, Wenhui Xu, Mengge Wang, Songmin Chen, Qiong Hu, Dongxue Han, Li Niu.  (2024)  Glycan-Evocated Metallization for Amplification-Free Electrochemical Detection of Glycoproteins at Low Concentration Levels.  ANALYTICAL CHEMISTRY,      [PMID:39432685] [10.1021/acs.analchem.4c04054]

101. Wanyu Li, Zhonghao Jiang, Zhuo Yan, Zhihao Chen, Lianhai Li, Dan Wang, Jilong Wang, Li Li, Huiling Yang, Junjie Deng, Jiantao Lin.  (2024)  Hydrogel based on M1 macrophage lysate and alginate loading with oxaliplatin for effective immunomodulation to inhibit melanoma progression, recurrence and metastasis.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:39276890] [10.1016/j.ijbiomac.2024.135542]

102. Zou Caomin, Chen Qianru, Li Jiasheng, Meng Jiang.  (2024)  Identification of potential anti-inflammatory components in Moutan Cortex by bio-affinity ultrafiltration coupled with ultra-performance liquid chromatography mass spectrometry.  Frontiers in Pharmacology,      [PMID:38384290] [10.3389/fphar.2024.1358640]

103. Daqian Zhou, Tao Liu, Yongliang Mei, Jiale Lv, Kang Cheng, Weiye Cai, Silong Gao, Daru Guo, Xianping Xie, Zongchao Liu.  (2024)  Identifying critical modules and biomarkers of intervertebral disc degeneration by using weighted gene co-expression network.  JOR Spine,  7  (4): (e70004).  [PMID:39430414] [10.1002/jsp2.70004]

104. Shaofei Yuan, Linjia Zhu, Yi Luo, Xiaoqiang Chen, Haibo Jing, Jiaqi Wang, Xiangyu Su, Meizhen Liang, Zhixiang Zhuang.  (2024)  Igniting tumour microenvironment in triple-negative breast cancer using a mannose/hyaluronic acid dual-coated Ganoderma polysaccharide-superparamagnetic iron oxide nanocomplex for combinational therapies.  JOURNAL OF DRUG TARGETING,      [PMID:39470031] [10.1080/1061186X.2024.2408721]

105. Qin Wang, Jianheng Ren, Xin Lin, Bin Zhang, Jiao Li, Yajun Weng.  (2024)  Inflammatory Stimulus-Responsive Polymersomes Reprogramming Glucose Metabolism Mitigates Rheumatoid Arthritis.  BIOMATERIALS,      [PMID:39163825] [10.1016/j.biomaterials.2024.122760]

106. Xu Han, Xiaqing Wu, Fanglin Liu, Huan Chen, Hongwei Hou.  (2024)  Inhibition of LPS-induced inflammatory response in RAW264.7 cells by natural Chlorogenic acid isomers involved with AKR1B1 inhibition.  BIOORGANIC & MEDICINAL CHEMISTRY,      [PMID:39396466] [10.1016/j.bmc.2024.117942]

107. Jiaxuan Li, Kuirong Mao, Xiandi Meng, Jialiang Wang, Mengfei Zhao, Yue Lv, Yanbao Xin, Huating Sun, Yuning Zhang, Yong-Guang Yang, Tianmeng Sun.  (2025)  Injectable hydrogel-assisted local lipopolysaccharide delivery improves immune checkpoint blockade therapy.  Acta Biomaterialia,      [PMID:39827003] [10.1016/j.actbio.2025.01.021]

108. Peng Chen, Yulai Wang, Jing Xie, Jiexin Lei, Benhong Zhou.  (2024)  Methylated urolithin A, mitigates cognitive impairment by inhibiting NLRP3 inflammasome and ameliorating mitochondrial dysfunction in aging mice.  NEUROPHARMACOLOGY,      [PMID:38636727] [10.1016/j.neuropharm.2024.109950]

109. Maochang Xu, Dan Ran, Jian Hu, Jingying Mao, Dehui Qiao, Zongquan Zhang, Xiaoya Liang, Li Zhang, Yu Nie, Hong Yang, Xiangyu Zhou, Chunhong Li.  (2024)  Multifunctional Prussian blue nanozymes alleviate atherosclerosis through inhibiting the inflammation feedback loop.  Journal of Materials Chemistry B,      [PMID:39692245] [10.1039/D4TB01926A]

110. Weiya Zeng, Ying Wang, Qing Zhang, Chengyi Hu, Jing Li, Jinwei Feng, Chenglu Hu, Yong Su, Jie Lou, Ling Long, Xing Zhou.  (2024)  Neutrophil Nanodecoys Inhibit Tumor Metastasis by Blocking the Interaction between Tumor Cells and Neutrophils.  ACS Nano,      [PMID:38422392] [10.1021/acsnano.3c08946]

111. Wenxiang Hong, Hongbo Ma, Zhaoxu Yang, Jiaying Wang, Bowen Peng, Longling Wang, Yiwen Du, Lijun Yang, Lijiang Zhang, Zhibin Li, Han Huang, Difeng Zhu, Bo Yang, Qiaojun He, Jiajia Wang, Qinjie Weng.  (2025)  Optineurin restrains CCR7 degradation to guide type II collagen-stimulated dendritic cell migration in rheumatoid arthritis.  Acta Pharmaceutica Sinica B,      [PMID:40370566] [10.1016/j.apsb.2025.02.004]

112. Hui Huang, Guanhua Wang, Dali Zeng.  (2024)  Peimine ameliorates LPS-induced acute lung injury by regulating Nrf2 and NF-κB pathways.  American Journal of Translational Research,  16  (10): (5385).  [PMID:39544744] [10.62347/ULSH9862]

113. Yang S. J., Ying J. L., Xie W. J..  (2024)  Rapamycin Regulates Lipopolysaccharide-Induced Microglial Phagocytosis In Vitro.  MOLECULAR BIOLOGY,      [PMID:] [10.1134/S0026893324700109]

114. Zhenwei Lan, Rui Yang, Hu Wang, Xingyang Xue, Yue Sun, Shumei Wang, Ying Zhang, Jiang Meng.  (2024)  Rapid identifying of COX-2 inhibitors from turmeric (Curcuma longa) by bioaffinity ultrafiltration coupled with UPLC-Q Exactive-Orbitrap-MS and zebrafish-based in vivo validation.  BIOORGANIC CHEMISTRY,      [PMID:38604020] [10.1016/j.bioorg.2024.107357]

115. Xinmei Duan, Xu Yang, Nianlian Mou, Yu Cao, Zhigui He, Li Zhu, Yuan Zhong, Kun Zhang, Kai Qu, Xian Qin, Qiao Chen, Yang Luo, Wei Wu.  (2024)  Reactive Oxygen Species-Triggered Carbon Dots-Based Biomimetic Nanotheranostic Agents for Atherosclerosis Management.  ADVANCED FUNCTIONAL MATERIALS,      [PMID:] [10.1002/adfm.202405629]

116. Zhao Kui, Qi Luming, Li Qi, Wang Yin, Qian Cheng, Shi Zhengjun.  (2024)  Self-absorbing multilayer skin-like composite with Phyllostachys nigra polysaccharides promotes wound healing.  Advanced Composites and Hybrid Materials,  7  (6): (1-18).  [PMID:] [10.1007/s42114-024-01018-x]

117. Jing Ye, Linjing Zheng, Weipeng Pan, Yayan Huang, Na Zhang, Dongda Yang, Yucheng Yang, Bingde Zheng, Xueqin Zhang, Meitian Xiao.  (2024)  Sulfated polysaccharide from Apostichopus japonicus viscera exhibits anti-inflammatory properties in vitro and in vivo.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:39276906] [10.1016/j.ijbiomac.2024.135500]

118. Hanzhe Liu, Zhenan Liu, Weilian Liang, Hokeung Tang, Lili Yu, Tong Wang, Lan Liu, Qingli Chen, Jia-Wei Wang, Xian-Zheng Zhang, Guo-Feng Luo, Zhengjun Shang.  (2024)  Tea leaf-derived nanovesicles for ferric-supply-amplified ICD and macrophage reprogramming to boost immunotherapy against head and neck squamous carcinoma.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2024.158469]

119. Dalin Sun, Dong Xing, Dandan Wang, Yuanyuan Liu, Bin Cai, Weimin Deng, Qinglin Hu, Wenjun Ma, Baofang Jin.  (2024)  The Protective Effects of Bushen Daozhuo Granule on Chronic Non-bacterial Prostatitis.  Frontiers in Pharmacology,      [PMID:38239203] [10.3389/fphar.2023.1281002]

120. Chenchen Zhao, Liang Sun, Yuxin Zhang, Xin Shu, Yujie Hu, Duo Chen, Zhi Zhang, Shengnan Xia, Haiyan Yang, Xinyu Bao, Jingwei Li, Yun Xu.  (2024)  Thymol improves ischemic brain injury by inhibiting microglia-mediated neuroinflammation.  BRAIN RESEARCH BULLETIN,      [PMID:39009094] [10.1016/j.brainresbull.2024.111029]

121. Geng Xiaoyu, Wang Ying, Li Huan, Song Liang, Luo Chen, Gu Xiaojie, Zhong Haixin, Chen Huilin, Chen Xinzhu, Wang Jianwei, Pan Zheng.  (2024)  Total iridoid glycoside extract of Lamiophlomis rotata (Benth) Kudo accelerates diabetic wound healing by the NRF2/COX2 axis.  Chinese Medicine,  19  (1): (1-19).  [PMID:38519940] [10.1186/s13020-024-00921-1]

122. Zixuan Dong, Song Liu, Xiaobing Liu, Dong He, Qi Chu, Linjie Zhong, Xiangyu Yu, Xiaoling Fu.  (2025)  Therapeutic Mitochondrial Transfer via Mesenchymal Stem Cell-Derived Microvesicles for Macrophage Modulation in Myocardial Infarction Complicated by Diabetes.  BIOMATERIALS,      [PMID:40706127] [10.1016/j.biomaterials.2025.123563]

123. Chang Peng, Ting Fang, Hanjie Sun, Dongkai Wang, Ji Li.  (2025)  Charge-Reversal Nanoassembly for Rheumatoid Arthritis Therapy via Cell-Free DNA Scavenging and Microenvironment Reprogramming.  BIOMATERIALS,      [PMID:40753785] [10.1016/j.biomaterials.2025.123591]

124. Mingxuan Huang, Huafeng Wang, Shicong Gui, Chujia Xu, Yi Chen, Shaohua Hu, Yubo Li.  (2025)  Electrochemical Biosensor Based on Ultrathin 2D CN-rGO@AgNPs for ROS Detection in Leukemia Cells.  ELECTROCHIMICA ACTA,      [PMID:] [10.1016/j.electacta.2025.146821]

125. Mengling Zhong, Mingmei Feng, Xinlin Chen, Yuxin Zhang, Yupeng Wang, Peizhi Yuan, Tianyao Zhang, Zhipeng Han, Chenglun Tang, Qi Zhang, Yang Sun.  (2025)  Cordycepin attenuated cyclophosphamide (CTX)-induced immunosuppression in mice via EGFR/Nrf2 antioxidant signaling pathway.  INTERNATIONAL IMMUNOPHARMACOLOGY,      [PMID:40695148] [10.1016/j.intimp.2025.115235]

126. Yue Wang, Xiangshu Cheng, Junchao Cai, Rui Peng, Lulu Wang, Jiarong Zhao, Tao Deng, Peng Xie.  (2025)  Near-Infrared Fluorescent GABA-Trp CDs with BBB Penetration for Treatment of Inflammatory Depression.  ADVANCED FUNCTIONAL MATERIALS,      [PMID:] [10.1002/adfm.202513805]

127. Bingyang Lu, Junchang Guo, Hao Yang, Xiao Han, Peng Yu, Shengjun Cheng, Zhenxu Shi, Dehui Wang, Weifeng Zhao, Jing Luo, Xu Deng.  (2025)  Antifouling blood-repellent surface enhanced gas exchange via gas-liquid direct diffusion in extracorporeal membrane oxygenation.  JOURNAL OF MEMBRANE SCIENCE,      [PMID:] [10.1016/j.memsci.2025.124566]

128. Bowen Sui, Yanling Sun, Jingzhi Wang, Yuan Cui, Haibo Xu, Daqing Zhao, Meichen Liu, Zhengqi Dong, Siming Wang, Shichao Liu.  (2025)  Complexes of Dendrobium officinale anthocyanins and polysaccharides: Structural characteristics, stability, antioxidant properties, and bioavailability.  Food Bioscience,      [PMID:] [10.1016/j.fbio.2025.107449]

129. Huadan Zhang, Congcong Sun, Kailin Li, Xianliang Luo, Zebin Guo, Song Miao, Baodong Zheng.  (2025)  Low-molecular-weight fucoidan prepared by ultrasonic/H2O2/VC degradation: Characterization, gut microbiota regulation, and anti-inflammatory effects.  Food Bioscience,      [PMID:] [10.1016/j.fbio.2025.107532]

130. Shangmin Yu, Xinying Wang, Linlin Lv, Tongyan Liu, Qingxiang Guan.  (2023)  Borneol-modified PEGylated graphene oxide as a nanocarrier for brain-targeted delivery of ginsenoside Rg1 against depression.  INTERNATIONAL JOURNAL OF PHARMACEUTICS,      [PMID:37527732] [10.1016/j.ijpharm.2023.123284]

131. Yongshuai Jing, Yameng Zhang, Meng Yan, Ruijuan Zhang, Beibei Hu, Shiguo Sun, Danshen Zhang, Yuguang Zheng, Lanfang Wu.  (2023)  Structural characterization of a heteropolysaccharide from the fruit of Crataegus pinnatifida and its bioactivity on the gut microbiota of immunocompromised mice.  FOOD CHEMISTRY,      [PMID:36780857] [10.1016/j.foodchem.2023.135658]

132. Chunyan Liao, Xiang Wang, Xueying Zhou, Dequan Wang, Ziyin Zhang, Yan Liu, Xiao Wu, Ying Chen, Yifeng Tan, Xin Dai, Pei Jing, Jie Pang, Xiao Xiao, Jie Liu, Xiaoming Liao, Shiyong Zhang.  (2022)  Dietary Antioxidant-Constructed Nanodrugs Can High-Efficiently Kill Cancer Cells while Protecting Noncancer Cells.  ACS Applied Materials & Interfaces,      [PMID:36315104] [10.1021/acsami.2c12043]

133. Aili Wang, Xi Ruan, Xuejiao Wang, Yuyu Ren, Chunjiao Shen, Kaiyi Zhang, Zhenjie Song, Bai Xiang, Yinling Ma, Feng Zhao.  (2024)  A one-stop integrated natural antimicrobial microneedles with anti-inflammatory, pro-angiogenic and long-term moisturizing properties to accelerate diabetic wound healing.  EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS,      [PMID:39134098] [10.1016/j.ejpb.2024.114448]

134. Baoting Dou, Hui Shen, Zhimin Li, Huanyu Cheng, Po Wang.  (2025)  Chemically modified DNAzymes-based electrochemical sensor for binary and highly sensitive detection of reactive oxygen species.  Chemical Science,      [PMID:39867952] [10.1039/D4SC05512H]

135. Taiping Li, Yougang Zhang, Rong Dong, Wenjie Bi, Songsong Wang, Kewu Zeng, Liwen Han.  (2024)  Identification and mechanistic exploration of key anti-inflammatory molecules in American ginseng: Impacts on signal transducer and activator of transcription 3 STAT3 phosphorylation and macrophage polarization.  PHYTOTHERAPY RESEARCH,      [PMID:38973353] [10.1002/ptr.8277]

136. Yuwei Zhao, Xingyu Zhu, Letao Hu, Fangyu Hao, Xianglei Ji, Xiaofang Hu, Meimei Luo, Linyu Zheng, Bo Xiao, Yingmei Wu, Changcan Shi, Hui Zhu, Nong Zhou, Weidong Li.  (2025)  Macrophage membrane-coated polydopamine nanomedicine for treating acute lung injury through modulation of neutrophil extracellular traps and M2 macrophage polarization.  Materials Today Bio,      [PMID:40225128] [10.1016/j.mtbio.2025.101708]

137. Yuehan Cui, Meng Song, Ruilai Liu, Zhenhao Xi, Ling Zhao, Lian Cen.  (2025)  Microfluidic development of liposome nanoparticles encapsulated with yam polysaccharide.  JOURNAL OF PHARMACEUTICAL SCIENCES,      [PMID:40054528] [10.1016/j.xphs.2025.103718]

138. Wu Tao, Wu Ji, Liu Li, Song Hongping.  (2024)  PDZK1 gene transfer ameliorates lipopolysaccharide-induced cholestasis in rats by rescuing hepatic ABC transporters.  BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY,      [PMID:39658368] [10.1093/bbb/zbae190]

139. Zhongjie Ji, Dong Yang, Hongru Wang, Zhenqian Sun, Linyang Song, Xin Liu, Hongliang Wang, Yunzhen Chen, Hongxin Cao, Yunhao You, Guangjun Jiao.  (2025)  A NIR-Responsive MXene-Based Hydrogel with Antibacterial and Repair-Promoting Functions for Treating Infected Wounds.  ADVANCED FUNCTIONAL MATERIALS,      [PMID:] [10.1002/adfm.202525674]

140. Shu-Long He, Guo-Bin Wang, Xue-Li Cheng, Lin-Lin Han, Wei Pan, Han-Yang Zou, Shi-Li Shen, Xian-Hong Pang, Yan Zhu.  (2025)  Aggregation-induced emission–twisted intramolecular charge transfer-activated fluorescent probe for analyzing mitochondrial viscosity in cells and zebrafish.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,      [PMID:39919476] [10.1016/j.saa.2025.125831]

141. Yingcui Bu, Yingyu Zhu, Yuxin Yang, Ting Wang, Xiaojiao Zhu, Xingxing Chen, Qiong Zhang, Mingdi Yang, Hongping Zhou.  (2025)  Mitochondrial SO2-Activated NIR Photodiagnostic Agent Harnessing Hydroxyl Radicals for Efficient Inflammation Eradication and Tumor Suppression.  ANALYTICAL CHEMISTRY,      [PMID:39743497] [10.1021/acs.analchem.4c06034]

142. Hong Wenxiang, Ma Hongbo, Li Zhibin, Du Yiwen, Xia Wenjing, Yin Han, Huang Han, Sun Zebing, Gai Renhua, Tong Lexian, Zhu Hong, Wang Jincheng, Yang Bo, He Qiaojun, Weng Qinjie, Wang Jiajia.  (2025)  Inhibition of EED-mediated histone methylation alleviates neuroinflammation by suppressing WNT-mediated dendritic cell migration.  Journal of Neuroinflammation,  22  (1): (1-20).  [PMID:40169990] [10.1186/s12974-025-03429-z]

143. Zhaoyu Wang, Qingxia Ji, Tingting Wang, Weiliang Hua, Yanhong Bi, Yongzhou Chi, Rongling Yang.  (2025)  A novel strategy for encapsulation and controlled release of Schisantherin a employing biofriendly polydopamine microparticles built on biomineralized calcium carbonate crystals.  JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY,      [PMID:] [10.1016/j.jddst.2025.106893]

144. Yang Du, Boshu Ouyang, Yao Liu, Yuzhen Yin, Yining Wu, Huishu Guo.  (2025)  A Hydrogel for Nitric Oxide Sensitization Chemotherapy Mediated by Tumor Microenvironment Changes in 3D Spheroids and Breast Tumor Models.  CURRENT PHARMACEUTICAL DESIGN,  31  (15): (1227-1238).  [PMID:39819416] [10.2174/0113816128348357241209050425]

145. Lushan Xu, Chenggang Li, ChenChen Zhao, Zibu Wang, Zhi Zhang, Xin Shu, Xiang Cao, Shengnan Xia, Xinyu Bao, Pengfei Shao, Yun Xu.  (2025)  Shionone protects cerebral ischemic injury through alleviating microglia-mediated neuroinflammation.  Chinese Journal of Natural Medicines,      [PMID:40274349] [10.1016/S1875-5364(25)60812-0]

146. Qimeng Tian, Hong Jiang, Yajun Luan, Jingge Sun, Yihang Sui, Ling Chen, Yongxiang Wang, Ninghua Tan.  (2025)  Vicenin-2 in Suhuang antitussive capsule attenuates mitophagy-dependent ferroptosis via LRP1 for treating post-infectious cough.  JOURNAL OF ETHNOPHARMACOLOGY,      [PMID:40288661] [10.1016/j.jep.2025.119880]

147. Jiao Wu, Xiaoyan Du, Fangchao Tong, Shuangling Zhang, Jiaojie Guo, Changchun Zhu, Rui Cui, Qirong Bai, Mengyao Chen, Li Meng, Linlin Song, Haichuan Yu.  (2025)  Chemical profiling, discriminant analysis, antioxidants, and anti-inflammatory activities of Lonicerae Japonicae Flos tea varieties.  Future Foods,      [PMID:] [10.1016/j.fufo.2025.100642]

148. Ziwei Kang, Ruoyan Xie, Yiming Cui, Zhiwei Chen, Jincheng Li, Jinyu Lv, Weijia Ye, Peixin Zhao, Keke Zhang, Jian Hong, Hengdong Qu.  (2025)  Macrophage PKM2 depletion ameliorates hepatic inflammation and acute liver injury in mice.  Frontiers in Pharmacology,      [PMID:40351417] [10.3389/fphar.2025.1546045]

149. Jiyou Wu, Xiaoguang Yang, Yuhua Yang.  (2025)  Enhancing Effects of Lactobacillus brevis CQPC12 on Motor Function in Mice Damaged by Antibiotics.  JOURNAL OF FOOD QUALITY,  2025  (1): (5049955).  [PMID:] [10.1155/jfq/5049955]

150. Shan Liu, Yue Zhang, Hao Zhou, Yating Ma, Fangzhou Huang, Tianyuan Lei, Qingbin Wang, Shangmin Yu.  (2025)  Ginsenoside Re Inhibits NLRP3 Inflammasome Activation in Depressive Mice by Promoting PINK1-Mediated Mitophagy.  JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,      [PMID:40298124] [10.1021/acs.jafc.4c09773]

151. Xinxin Chen, Jiang Sun, Tingxian Ye, Fanzhu Li.  (2025)  Neutrophil-Camouflaged Stealth Liposomes for Photothermal-Induced Tumor Immunotherapy Through Intratumoral Bacterial Activation.  Pharmaceutics,  17  (5): (614).  [PMID:40430905] [10.3390/pharmaceutics17050614]

152. Peng Chen, Wenhao Xiao, Fanzhao Zou, Jiexin Lei, Fuchao Chen, Ruhong Zhang.  (2025)  Methylated urolithin a attenuates lipopolysaccharide-induced memory impairment and behavioral disorders by inhibiting mitochondrial inflammation through the Drp1/HK1/NLRP3 pathway.  Journal of Functional Foods,      [PMID:] [10.1016/j.jff.2025.106851]

153. Heng Wang, Zhaofei Liu, Xiangjun Xu, Haitao Zhang, Lei He, Ming Li.  (2025)  Calycosin Protects Against Chronic Prostatitis via Regulating Cellular Pyroptosis.  AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY,  93  (5): (e70084).  [PMID:40349356] [10.1111/aji.70084]

154. Qiang Zhang, Tuo Wang, Junyu Ren, Yanru Guo, Ziyi Yin, Chenrui Zhang, Honglin Fan, Yinting Ren, Junlong Da, Narisu Hu.  (2025)  Multifunctional astragalus polysaccharide composited microneedle promotes oral ulcers healing by inhibiting ferroptosis via Nrf2/HO-1/SLC7A11 axis.  Materials Today Bio,      [PMID:40510835] [10.1016/j.mtbio.2025.101873]

155. Niu Mengya, Zhao Luo, Gong Shuang, Liu Xinxin, Zheng Cuixia, Jiao Jiannan, Wang Fangfang, Wang Lei.  (2025)  Oral administration of probiotic spores-based biohybrid system for efficient attenuation of Salmonella Typhimurium-induced colitis.  JOURNAL OF NANOBIOTECHNOLOGY,  23  (1): (1-18).  [PMID:40414932] [10.1186/s12951-025-03468-x]

156. Meili Yang, Zuzhe Kang, Xinpei Zhong, Sirui Bai, Dong-En Wang, Qin Tu, Sheng Chen, Jinyi Wang, Mao-Sen Yuan.  (2025)  Visualizing GSH-ONOO− Redox and Tracking Lesion-Remedy of Acute Kidney Oxidative Injury Based on a Dual-Site Chemosensor.  Advanced Healthcare Materials,      [PMID:40424091] [10.1002/adhm.202500907]

157. Cheng Chen, Qingyun Wei, Zhen Zhu, Wenhui Wu, Tiantian Gong, Yangbo Lv, Aimei Zhang, Chunping Hu, Qichen Zhan, Tao Cao, Peng Cao.  (2025)  A thermoresponsive magnetic nanocarrier with the DNA-mimetic base pairing-guided controlled release of methotrexate in the treatment of rheumatoid arthritis.  JOURNAL OF CONTROLLED RELEASE,      [PMID:40513670] [10.1016/j.jconrel.2025.113952]

158. Wei Zhang, Xiangbing Wu, Wenming Li, Haifeng Zhang, Yijun Wang, Jing Xu, Wenhao Li, Yi Qin, Zebin Wu, Gaoran Ge, Shujun Lv, Lu Mao, Liangliang Wang, Dechun Geng.  (2025)  Pinosylvin Inhibits Inflammatory and Osteoclastogenesis via NLRP3 Inflammasome.  Advanced Science,      [PMID:40492417] [10.1002/advs.202501532]

159. Yunhe Lin, Chunlin Wang, Siwei Li, Shuaimei Xu, Bo Jia, Han Zhang, Binbin Gong, Yu Lu, Chengxia Liu, Zhongjun Liu.  (2025)  Therapeutic effects of an injectable multifunctional thermosensitive hydrogel loaded with ascorbic acid carbon quantum dots and chitosan/chondroitin sulfate complex on periodontitis.  CARBON,      [PMID:] [10.1016/j.carbon.2025.120570]

160. Yanxue Si, Ruitao Cha, Pai Zhang, Fengshan Zhou, Wenbing Yuan, Xingyu Jiang.  (2025)  CD-MOF Based pH/ROS Sensitive 5-ASA Delivery System for Ulcerative Colitis Therapy.  Advanced Healthcare Materials,      [PMID:40545915] [10.1002/adhm.202501160]

161. Renjie Cao, Tingting Zhao, Ying Wang, Shaofei Song, Yuan Li, Mengling Hou, Yanxin Zhang, Sengpeng Wong, Siqi Wang, Yuran Wang, Hong Peng, Min Huang, Yiming Jiang.  (2025)  Constitutive Androstane Receptor in Macrophages Regulates Toll-Like Receptor 4-Mediated Innate Immune Responses Against Endotoxemic Liver Injury.  Advanced Science,      [PMID:40820881] [10.1002/advs.202506725]

162. Shuo Yang, Jiaxi Han, Miao Xue, Yiming Zhang, Aohan Yan, Xiyu Gao, Jiangmei He, Xiaojia Sun, Shoupeng Fu, Dianfeng Liu, Bingxu Huang.  (2025)  Coixol ameliorates dopaminergic neurodegeneration by inhibiting neuroinflammation and protecting mitochondrial function.  Frontiers in Pharmacology,      [PMID:41111524] [10.3389/fphar.2025.1657910]

163. Xu Guobin, Wang Junlong, Gu Na, Yang Tiansong.  (2025)  NSUN7-mediated m5C methylation of NLRP3 promotes pyroptosis in ovarian granulosa cells in polycystic ovary syndrome.  Scientific Reports,  15  (1): (1-11).  [PMID:41062800] [10.1038/s41598-025-19209-x]

164. Lamei Liu, Min Zhang, Yan Zhou, Lin He, Mingjian Chen, Yuchen Wu, Guanyu Yin, Hui He, Lanlin Qi, Bin Zhang, Xiaoxiao He, Kemin Wang.  (2025)  An injectable ROS-responsive hydrogel comprising chondroitin sulfate@resveratrol liposome package for osteoarthritis alleviation.  BIOMATERIALS,      [PMID:41075429] [10.1016/j.biomaterials.2025.123766]

165. Yuling Wang, Jun Deng, Xi Wang, Dan Luo, Shujing Ren, Xueping Guo, Dan Chen, Rui Liu, Siyuan Chen, Wei Liu.  (2025)  Mini Hyaluronic Acid-modified Nanoliposomes for Topical Co-Delivery of Paeonol, Totarol and Ergothioneine: A Synergistic Adjuvant Therapy for Acne.  JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY,      [PMID:] [10.1016/j.jddst.2025.107648]

166. Kai Xie, Zhengwei Liu, Kai Chen, Junyi Che, Yongxiang Wang.  (2025)  A matrix metalloproteinase-responsive hydrogel with spatially orchestrated delivery of stem cells and raleukin for enhanced bone regeneration.  Materials Today Bio,      [PMID:41293488] [10.1016/j.mtbio.2025.102475]

167. Jing Chen, Yuan Ma, Zhi-Min Rao, Song-Lin Jiang, Ying-Jun Lou, Karim Malik, Arman Chowdhury, Hua-Zhong Ying, Chen-Huan Yu.  (2025)  A new fucosylated glucuronoxylomannan from the fruit bodies of Tremella aurantia: structural characterization and immunoenhancing activity on seasonal influenza mRNA vaccine.  CARBOHYDRATE POLYMERS,      [PMID:41320418] [10.1016/j.carbpol.2025.124660]

168. Jingwei Wu, Zhuoting Zhang, Hanglian Lan, Ting Sun, Zhihui Li, Weilian Hung, Hangyu Hu, Zhennai Yang, Jian Zhang.  (2025)  Response surface analysis and anti-inflammatory activity of a potential postbiotic exopolysaccharide produced by probiotic Lacticaseibacillus paracasei K56.  Journal of Functional Foods,      [PMID:] [10.1016/j.jff.2025.107126]

169. Peng Pan, Sixv Ding, Wang Yang, Yibo Wang, Hua Qian, Ayang Zhao, Wengang Ding.  (2025)  Flurbiprofen@ZIF-8 nanoformulation with potential for analgesia.  BMC Anesthesiology,      [PMID:41331754] [10.1186/s12871-025-03467-3]

170. Cai Cheng, Yan Lin, Xin Chen, Yang Xie, Xing Jiang, Jinting Chen, Yanling Wu, Zaiyi Luo, Jiayi Xu, Zhirong Zhang, Changguang Wang, Pei Jing, Zhongbing Liu, Xingjie Du, Jun Jiang, Xiaoduan Sun, Xiangyu Zhou, Zhirong Zhong.  (2025)  Nanoformulated resveratrol enhanced the treatment of atherosclerosis.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2025.172076]

171. Ting Pan, Xianwei Zhu, Ying Sui, Zhixin Zhang, Yongtao Su.  (2025)  Tanshinone IIA Accelerates Diabetic Wound Healing via Suppression of Macrophage NLRP3 Inflammasome Activity.  BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,      [PMID:41435748] [10.1016/j.bbrc.2025.153171]

172. Qian-ni Wu, Zi-ren Feng, Qin Tang, Jiu-ping Jin, Xue-hui Liu, Zhi-bin Mai, Sheng-nan Zhao, Yong-qi Lan, Kai-xin Chen, Jin-duan Lin, Peng-cheng Xu, Ji-jun Fu.  (2025)  Redox-Active Cerium Oxide Nanoparticles Protect Against Acetaminophen-Induced Acute Liver Injury by Modulating Oxidative Stress and Inflammatory Pathways.  MOLECULAR PHARMACEUTICS,      [PMID:41472557] [10.1021/acs.molpharmaceut.5c01647]

173. Yuze Luo, Ying Wang, Cheng Jin, Ke Yang, Zefeng Wang, Yinbang Zheng, Junqin Li, Chunlei Ou, Li Wang, Dinggeng He.  (2026)  pH-responsive tannic acid-iron nanozymes capable of self-adaptive regulation of oxidative stress for enhancing the treatment of MRSA-infected wound via disrupting PBP2a to restore methicillin sensitivity.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2026.173215]

174. Qiaoyu Sun, Qingqing Zhou, Sitong Ge, Danli Wu, Ping Li, Qing Gu.  (2026)  Indole-3-Acetic Acid Improves Intestinal Inflammation and Intestinal Barrier Dysfunction In Vitro via the AHR/NF-κB Signaling Pathway.  Food Frontiers,  7  (1): (e70225).  [PMID:] [10.1002/fft2.70225]

175. Hai Zhou, Chaoyang Huang, Yanqi Chen, Tingzi Zhao, Fengyi Zhu, Gong Jun, Jinrong Zhang, Yingsong Pan, Qiulan Wen, Lei Yang, Huihui Zhang, Lianglong Chen.  (2026)  An In Situ Embedded B-MOF Sponge With Shape-Memory for All-in-One Diabetic Wound Therapy.  Advanced Healthcare Materials,      [PMID:41568870] [10.1002/adhm.202505350]

176. Yuan-yu Yang, Li-guo Li, Shang Li, Ya Su, Li-ming Liu, Quan Tang, Rui Qiu, Yong-Biao Li, Yong Cheng, Hui Zhou.  (2026)  Siraitia grosvenorii extract (Sweet Mogrosides) alleviates LPS-induced depressive-like behaviors through modulating neuroinflammation-pyroptosis axis.  Journal of Functional Foods,      [PMID:] [10.1016/j.jff.2026.107170]

177. Chuang Liu, Wenqi Xie, Zheng Cao, Yicheng Lv, Xiaoling Fu.  (2026)  Fusogenic Hybrid Gelled Nanovesicles Combining Mesenchymal Stromal Cell Cargo with Cholesterol-Modified Macrophage Membranes for Targeted Myocardial Infarction Therapy.  ACS Nano,      [PMID:41674372] [10.1021/acsnano.5c17217]

178. Weizuo Liao, Yuxuan Xiao, Qunying Leng, Xinxin Yin, Ziyin Li, Junfeng Deng, Shixiong Zheng, Ruixue Liu, Biao Chen, Shiwei Li, Qiang Niu, Xingfen Yang, Zhini He.  (2026)  Enhanced Sensitivity and Human Relevance: a TNF-α-Induced HaCaT Keratinocyte Model for Screening Anti-Inflammatory Cosmetic Materials.  JOURNAL OF APPLIED TOXICOLOGY,      [PMID:41742400] [10.1002/jat.70120]

179. Chao Song, Xiaofei Wu, Chaoqi Chen, Baoxin Shen, Yuheng He, Fei Liu, Feng Chen, Zhijiang Fu, Zongchao Liu.  (2026)  Resveratrol Alleviates Intervertebral Disc Degeneration by Targeting NCOA4-Mediated Ferritinophagy Through Dual Antioxidant and Anti-Inflammatory Effects.  Drug Design Development and Therapy,      [PMID:] [10.2147/DDDT.S575321]

180. Kebi Li, Xiaopei Wu, Peijun Xiong, Hanping He, Zinuo Xia, Yang Zhou, Liang Zhao, Jiaxin Li, Tao Liu, Hongwei Shi, Peihu Xu, Haixing Xu.  (2026)  Electroactive Dual-Drug Hydrogel-PLA Conduit for Nerve Regeneration.  JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS,  114  (4): (e70066).  [PMID:] [10.1002/jbm.b.70066]

181. Sheng Yin, Yashi Wang, Hao Guo, Shiyong Zhang.  (2026)  Cross-Linked Lipoic Acid Trisulfide Nanoparticles against Acute Liver Injury by Multipathway Regulation.  CHEMISTRY OF MATERIALS,      [PMID:] [10.1021/acs.chemmater.5c03307]

182. Xiaoliang Zhao, Lixia Xiong, Haidong Wen, Yuanyuan Ma, Yuxin Wang, Cunjin Wang, Pengcheng Shao, Jing Zhang, Yuhui Zhao, Ji Zhang, Weijie Zhang.  (2026)  Ultrasound-Assisted Extraction, Chemical Modification, Structural Characterization, and Activity Studies of Polysaccharides From Corn Silk.  CHEMISTRY & BIODIVERSITY,  23  (3): (e03369).  [PMID:] [10.1002/cbdv.202503369]

183. Liang Chen, Shuai Tan, Jianwei Wang, Xiang Shi, Zhou Zhang, Jinjiang He, Haixing Wang.  (2026)  Mechanistic study of locally transplanted bone marrow mesenchymal stem cells combined with erythropoietin in acute spinal cord injury.  NEUROLOGICAL RESEARCH,      [PMID:] [10.1080/01616412.2026.2622479]

184. Shangping Xing, Xue Cheng, Shiyu Hou, Lidan Qin, Juan Wang, Yue Ding, Zhangyang Shen, Ziteng Dai, Xiaoming Huang, Yanying Liu, Dan Zhu.  (2026)  Identification of monomethylsulochrin as a novel agent to ameliorate DSS-induced ulcerative colitis through dual modulation of the IL-17/TNF pathway and gut microbiota.  INTERNATIONAL IMMUNOPHARMACOLOGY,      [PMID:] [10.1016/j.intimp.2026.116451]

185. Kai Dong, Zelin Guan, Danyang Wang, Jinyao Sun, Ying Zhang, Cuiyu You, Yuanming Xing.  (2026)  A “One-Stone-Three-Birds” Inspired Nanoplatform for Multi-Targeted Ulcerative Colitis Therapy via Combined AhR Activation and ROS Scavenging.  Biomaterials Research,      [PMID:] [10.34133/bmr.0356]