β-Nicotinamide adenine dinucleotide phosphate - Moligand™, ≥90% , CAS No.53-59-8

CAS: 53-59-8 Cat. No.: N303921 Molecular Weight: 743.41 EC Number: 200-178-1

GRADE & PURITY Moligand™, ≥90%

Synonyms

Coenzyme II | NADP | TPN | BRN 3885115 | nicotinamide adenine dinucleotide phosphate | SCHEMBL7869 | TPN-ox | nadp nicotinamide-adenine-dinucleotide phosphate | 944A1E1D-E8B9-42AF-B61D-7C4242AB099A | Adenosine 5'-(trihydrogen diphosphate), 2'-(dihydrogen

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Specifications

Synonyms

Coenzyme II | NADP | TPN | BRN 3885115 | nicotinamide adenine dinucleotide phosphate | SCHEMBL7869 | TPN-ox | nadp nicotinamide-adenine-dinucleotide phosphate | 944A1E1D-E8B9-42AF-B61D-7C4242AB099A | Adenosine 5'-(trihydrogen diphosphate), 2'-(dihydrogen

Specifications & Purity

Moligand™, ≥90%

Biochemical and Physiological Mechanisms

β-nicotinamide adenine dinucleotide 2 ′-phosphate (NADP+) and β-nicotinamide adenine dinucleotide 2 ′-phosphate reduction (NADPH) form a coenzyme redox pair (NADP+:NADPH), which participates in a wide range of enzyme-catalyzed redox reactions. NADP+/NADPH

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Grade

Moligand™

Purity

≥90%

Names and Identifiers

• Pubchem Sid: 488179953
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/488179953
• Canonical Smiles: C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)([O-])OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)OP(=O)(O)O)O)O)O)C(=O)N
• IUPAC Name: [[(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-3-hydroxy-4-phosphonooxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(2R,3S,4R,5R)-5-(3-carbamoylpyridin-1-ium-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphate
• InChIKey: XJLXINKUBYWONI-NNYOXOHSSA-N
• INCHI: 1S/C21H28N7O17P3/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(44-46(33,34)35)14(30)11(43-21)6-41-48(38,39)45-47(36,37)40-5-10-13(29)15(31)20(42-10)27-3-1-2-9(4-27)18(23)32/h1-4,7-8,10-11,13-16,20-21,29-31H,5-6H2,(H7-,22,23,24,25,32,33,34,35,36,37,38,39)/t10-,11-,13-,14-,15-,16-,20-,21-/m1/s1
• Isomeric SMILES: C1=CC(=C[N+](=C1)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)([O-])OP(=O)(O)OC[C@@H]3[C@H]([C@H]([C@@H](O3)N4C=NC5=C(N=CN=C54)N)OP(=O)(O)O)O)O)O)C(=O)N
• Molecular Weight: 743.41
• Reaxy-Rn: 25351893
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=25351893&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Nucleosides, nucleotides, and analogues
    • Class (5'->5')-dinucleotides

• Kingdom: Organic compounds
• Superclass: Nucleosides, nucleotides, and analogues
• Class: (5'->5')-dinucleotides
• Subclass: Not available
• Intermediate Tree Nodes: Not available
• Direct Parent: (5'->5')-dinucleotides
• Alternative Parents: Purine nucleotide sugars Purine ribonucleoside diphosphates Purine ribonucleoside 2',5'-bisphosphates Nicotinamide nucleotides Pentose phosphates Glycosylamines Monosaccharide phosphates 6-aminopurines Organic pyrophosphates Nicotinamides Monoalkyl phosphates Aminopyrimidines and derivatives Imidolactams Pyridinium derivatives N-substituted imidazoles Heteroaromatic compounds Tetrahydrofurans Secondary alcohols Oxacyclic compounds Azacyclic compounds Carboximidic acids Hydrocarbon derivatives Organic oxides Organic zwitterions Organopnictogen compounds Primary amines
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: (5'->5')-dinucleotide - Purine nucleotide sugar - Purine ribonucleoside 2',5'-bisphosphate - Purine ribonucleoside bisphosphate - Purine ribonucleoside diphosphate - Nicotinamide-nucleotide - Pyridine nucleotide - Pentose phosphate - Pentose-5-phosphate - Glycosyl compound - N-glycosyl compound - 6-aminopurine - Monosaccharide phosphate - Organic pyrophosphate - Imidazopyrimidine - Nicotinamide - Purine - Aminopyrimidine - Monoalkyl phosphate - Monosaccharide - N-substituted imidazole - Organic phosphoric acid derivative - Pyrimidine - Alkyl phosphate - Phosphoric acid ester - Pyridinium - Pyridine - Imidolactam - Imidazole - Tetrahydrofuran - Heteroaromatic compound - Azole - Secondary alcohol - Carboximidic acid derivative - Oxacycle - Azacycle - Organoheterocyclic compound - Carboximidic acid - Primary amine - Alcohol - Organopnictogen compound - Organic oxygen compound - Organic nitrogen compound - Amine - Organonitrogen compound - Organooxygen compound - Organic oxide - Organic zwitterion - Hydrocarbon derivative - Aromatic heteropolycyclic compound
• Description: This compound belongs to the class of organic compounds known as (5'->5')-dinucleotides. These are dinucleotides where the two bases are connected via a (5'->5')-phosphodiester linkage.
• External Descriptors: NADP

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Associated Targets(Human)

DHFR Tclin Dihydrofolate reductase (3072 Activities)

Discover Target: DHFR

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CHAT Tchem Choline acetylase (63 Activities)

Discover Target: CHAT

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Homo sapiens (32628 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 (2672 Activities)

Discover Target: SLCO1B1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 (2517 Activities)

Discover Target: SLCO1B3

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Fdft1 Squalene synthetase (34 Activities)

Discover Target: Fdft1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mus musculus (284745 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

panE Ketopantoate reductase (28 Activities)

Discover Target: panE

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

rep Replicase polyprotein 1ab (378 Activities)

Discover Target: rep

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Chemical and Physical Properties

• Solubility: Soluble in water and methanol, slightly soluble in ethanol, insoluble in ether
• Sensitivity: heat sensitive
• Molecular Weight: 743.400 g/mol
• XLogP3: -7.100
• Hydrogen Bond Donor Count: 8
• Hydrogen Bond Acceptor Count: 21
• Rotatable Bond Count: 13
• Exact Mass: 743.075 Da
• Monoisotopic Mass: 743.075 Da
• Topological Polar Surface Area: 368.000 Ų
• Heavy Atom Count: 48
• Formal Charge: 0
• Complexity: 1290.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 8
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

References

1. Huang Mingjun, Wu Fanchang, Zuo Xue, Liu Jinman, Yu Wenqian, Xie Ruiye, Liu Guoqing, Tan Qiwen, Wang Qi, Liang Yong.  (2023)  Quercetin Simultaneously Inhibited Cytochrome P450 and P-Glycoprotein to Improve the Pharmacokinetics of Osthole in Rat Plasma.  Revista Brasileira de Farmacognosia-Brazilian Journal of Pharmacognosy,      [PMID:] [10.1007/s43450-023-00487-3]

2. Lai Liang, Zhang Mengyun, Liu Chusheng, Qu Jiahuan, Xu Dongsheng, Jiang Zhengjin.  (2023)  A comprehensive evaluation of a polymeric zwitterionic hydrophilic monolith for nucleotide separation.  ANALYTICAL SCIENCES,      [PMID:37843729] [10.1007/s44211-023-00430-5]

3. Yan Shi, Wei Xu, Dawei Ni, Wenli Zhang, Cuie Guang, Wanmeng Mu.  (2023)  Identification and application of a novel deoxynivalenol-degrading enzyme from Youhaiella tibetensis.  FOOD CHEMISTRY,      [PMID:37783127] [10.1016/j.foodchem.2023.137609]

4. Jiang Zhu, Ruinan Qu, Yawei Wang, Ruoyao Ni, Kai Tian, Chan Yang, Mei Li, Michael Kristensen, Xinghui Qiu.  (2023)  Up-regulation of CYP6G4 mediated by a CncC/maf binding-site-containing insertion confers resistance to multiple classes of insecticides in the house fly Musca domestica.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:37769776] [10.1016/j.ijbiomac.2023.127024]

5. Nawaz Muhammad, Jiang Yipeng, Xiao Ying, Yu Hao, Wang Zikang, Hu Kun, Zhang Tianao, Hu Jiajun, Gao Min-Tian.  (2023)  Influence of Different Pretreatment Steps on the Ratio of Phenolic Compounds to Saccharides in Soluble Polysaccharides Derived from Rice Straw and Their Effect on Ethanol Fermentation.  APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY,  195  (7): (4552-4569).  [PMID:36701092] [10.1007/s12010-023-04337-9]

6. Zhongzhong Lu, Jincong Yan, Mingsheng Xu, Lina Sun, Jihuan Liu, Ye Zhang, Lei Shi, Xifeng Fei, Yi Cao, Renjun Pei.  (2022)  Hypoxia-Responsive Aggregation of Iron Oxide Nanoparticles for T1-to-T2 Switchable Magnetic Resonance Imaging of Tumors.  ACS Applied Nano Materials,      [PMID:] [10.1021/acsanm.2c03850]

7. Jiang Zhu, Jing Feng, Kai Tian, Chong Li, Mei Li, Xinghui QIU.  (2022)  Functional characterization of CYP6G4 from the house fly in propoxur metabolism and resistance.  PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY,      [PMID:36127048] [10.1016/j.pestbp.2022.105186]

8. Xinxing Gao, Qianqian Pei, Nianqing Zhu, Yi Mou, Jilei Liang, Xin Zhang, Shoushuai Feng.  (2022)  Efficient Asymmetric Synthesis of (S)-N-Boc-3-hydroxypiperidine by Coexpressing Ketoreductase and Glucose Dehydrogenase.  Catalysts,  12  (3): (304).  [PMID:] [10.3390/catal12030304]

9. Xiaoxiang Hu, Yajun Bai, Tai-Ping Fan, Xiaohui Zheng, Yujie Cai.  (2020)  A novel type alanine dehydrogenase from Helicobacter aurati: Molecular characterization and application.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:32534087] [10.1016/j.ijbiomac.2020.06.067]

10. Jie Liu, Yuli Wang, Xiaoxue Liu, Qunhui Yuan, Yang Zhang, Yingchun Li.  (2019)  Novel molecularly imprinted polymer (MIP) multiple sensors for endogenous redox couples determination and their applications in lung cancer diagnosis.  TALANTA,      [PMID:30952300] [10.1016/j.talanta.2019.03.018]

11. Kai Tian, Jiang Zhu, Mei Li, Xinghui Qiu.  (2019)  Capsaicin is efficiently transformed by multiple cytochrome P450s from Capsicum fruit-feeding Helicoverpa armigera.  PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY,      [PMID:31027574] [10.1016/j.pestbp.2019.02.015]

12. Lijun Geng, Xudong Yu, Yajuan Li, Yanqiu Wang, Yongquan Wu, Jujie Ren, Fengfeng Xue, Tao Yi.  (2019)  Instant hydrogel formation of terpyridine-based complexes triggered by DNA via non-covalent interaction.  Nanoscale,  11  (9): (4044-4052).  [PMID:30768104] [10.1039/C8NR08532C]

13. Huan Zhao, Ying Xu, Shuangjun Lin, Jim C. Spain, Ning-Yi Zhou.  (2018)  The molecular basis for the intramolecular migration (NIH shift) of the carboxyl group during para-hydroxybenzoate catabolism.  MOLECULAR MICROBIOLOGY,  110  (3): (411-424).  [PMID:30070064] [10.1111/mmi.14094]

14. Zheng Liandan, Lin Jinping, Zhang Baoqi, Kuang Yuyao, Wei Dongzhi.  (2018)  Identification of a yeast old yellow enzyme for highly enantioselective reduction of citral isomers to (R)-citronellal.  Bioresources and Bioprocessing,  5  (1): (1-12).  [PMID:] [10.1186/s40643-018-0192-x]

15. Chen Zhao, Yan Yang, Linfang Wei, Qinghua Guo, Hao Fang, Shaolin Chen, Qiang Hua.  (2017)  Simultaneous determination of intracellular nucleotides and coenzymes in Yarrowia lipolytica producing lipid and lycopene by capillary zone electrophoresis.  JOURNAL OF CHROMATOGRAPHY A,      [PMID:28760603] [10.1016/j.chroma.2017.07.074]

16. Danyu Kang, Ting Geng, Yuanpei Lian, Yanjing Li, Gang Ding, Wenzhe Huang, Shiping Ma, Zhenzhong Wang, Zheng Ma, Wei Xiao.  (2016)  Direct inhibition of Re Du Ning Injection and its active compounds on human liver cytochrome P450 enzymes by a cocktail method.  BIOMEDICAL CHROMATOGRAPHY,  31  (7): (e3905).  [PMID:27891633] [10.1002/bmc.3905]

17. Jianyong Li, Xiaojun Kong, Xiwang Li, Yajun Yang, Jiyu Zhang.  (2013)  Genotoxic evaluation of aspirin eugenol ester using the Ames test and the mouse bone marrow micronucleus assay.  FOOD AND CHEMICAL TOXICOLOGY,      [PMID:24140966] [10.1016/j.fct.2013.10.010]

18. Tengfei Xiong, Mingyue Yu, Mei Li, Christopher A. Reilly, Xinghui Qiu.  (2024)  CYP6B6 mediated adaptation to capsaicinoids in the generalist Helicoverpa armigera and specialist H. assulta: Transcriptional response and metabolic detoxification.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:39631573] [10.1016/j.ijbiomac.2024.138286]

19. Chun-Xian Cai, Zi-Wen Zhou, Chun-Xiu Liu, Yun-Jie Wei, Xiao-Qi Yu, Li-Hong Zhou, Na Wang.  (2024)  Development of compatible photocatalyst-enzyme hybrid system via Intensifying enzyme tolerance for enhanced chiral alcohol synthesis.  JOURNAL OF CATALYSIS,      [PMID:] [10.1016/j.jcat.2024.115932]

20. Bai Rui, Li Junpeng, Chen Wei, He Yi, Zhou Xudong, Tian Xiaochun, Ren Chongyuan, Chen Liqi, Xiao Yong, Zhao Feng.  (2025)  Dual roles of the sacrificial agent in efficient solar-to-chemical production by nonphotosynthetic Moorella thermoacetica.  Science China-Chemistry,      [PMID:] [10.1007/s11426-024-2500-3]

21. Jiancong Ni, Shengxiu Huang, Weiqiang Yang, Qiaoling Chen, Zhenyu Lin.  (2024)  Electrochemiluminescence Detecting and Imaging of Yeast Metabolism Indicated by Endogenetic Co-reactant.  ANALYTICAL CHEMISTRY,      [PMID:39700391] [10.1021/acs.analchem.4c05663]

22. Feng Xinming, Cui Xinyu, Wang Kun, Liu Juanjuan, Meng Dongdong.  (2024)  Enzymatic characterization of a thermostable 6-phosphogluconate dehydrogenase from Hydrogenobacter thermophilus and its application for NADH regeneration.  3 Biotech,  15  (1): (1-8).  [PMID:39650808] [10.1007/s13205-024-04165-6]

23. Junxia Liu, Peng Li, Xiao Li, Yanli Xie, Fred Mwabulili, Shumin Sun, Yuhui Yang, Weibin Ma, Qian Li, Hang Jia.  (2024)  Expression, characterization, and application of an aldo-keto reductase mined from Bacillus velezensis Vel-HNGD-F2 for deoxynivalenol biodegradation.  FOOD AND CHEMICAL TOXICOLOGY,      [PMID:39613245] [10.1016/j.fct.2024.115159]

24. Tengfei Xiong, Mingyue Yu, Jiang Zhu, Kai Tian, Mei Li, Xinghui Qiu.  (2024)  Functional characterization of Helicoverpa assulta CYP6B6 in insecticide metabolism.  PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY,      [PMID:38685236] [10.1016/j.pestbp.2024.105857]

25. Chenyu Song, Wei Xu, Cuie Guang, Ting Xue, Wanmeng Mu.  (2024)  Identification and application of a novel patulin degrading enzyme from Cyberlindnera fabianii.  FOOD RESEARCH INTERNATIONAL,      [PMID:39147475] [10.1016/j.foodres.2024.114846]

26. Kai Tian, Jiang Zhu, Xinghui Qiu.  (2024)  Metabolism of Furanocoumarins by Three Recombinant CYP9A Proteins From the Polyphagous Cotton Bollworm Helicoverpa armigera.  ARCHIVES OF INSECT BIOCHEMISTRY AND PHYSIOLOGY,  117  (3): (e70004).  [PMID:39494619] [10.1002/arch.70004]

27. Wen-Kai Liu, Xiu-Xin Ren, Lian Xu, Juan Lin.  (2025)  Modular cascade with engineered HpaB for efficient synthesis of hydroxytyrosol.  BIOORGANIC CHEMISTRY,      [PMID:39764921] [10.1016/j.bioorg.2025.108125]

28. Wen-Kai Liu, Bing-Mei Su, Xin-Qi Xu, Lian Xu, Juan Lin.  (2024)  Multienzymatic Cascade for Synthesis of Hydroxytyrosol via Two-Stage Biocatalysis.  JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,      [PMID:38940657] [10.1021/acs.jafc.4c04228]

29. Xuecai Wei, Xiaoyang Yue, Quan Yuan, Ying He, Li Ma, Liya Zhou, Guanhua Liu, Yunting Liu, Yanjun Jiang.  (2024)  Multigram synthesis of ethyl (S)-4-chloro-3-hydroxybutanoate in a monophasic aqueous system using a robust NADH-dependent alcohol dehydrogenase from Pseudomonas bacterium.  Molecular Catalysis,      [PMID:] [10.1016/j.mcat.2024.114067]

30. Shuchen Yu, Yitong Jiang, Qian Li, Mengmeng Li, Jiamin Su, Shicong Lai, Zhihua Gan, Zhenshan Ding, Qingsong Yu.  (2024)  Nano-sensitizer with self-amplified drug release and hypoxia normalization properties potentiates efficient chemoradiotherapy of pancreatic cancer.  BIOMATERIALS,      [PMID:38823195] [10.1016/j.biomaterials.2024.122634]

31. Lixin Kang, Haoran Li, Kexin Lin, Shen Hu, Song Liu, Yuben Qiao, Ying Wang, Aitao Li.  (2025)  Regioselectivity Switching in CYP107Pdh-Catalyzed VD3 Hydroxylation: A Structure-Guided Approach To Improve Calcidiol Production.  ACS Catalysis,      [PMID:] [10.1021/acscatal.5c00444]

32. SunHongzheng , HanLongsen , GuoYueshuai , AnHuiqing , WangBing , ZhangXiangzheng , LiJiashuo , JiangYingtong , WangYue , SunGuangyi , ZhuShuai , TangShoubin , GeJuan , ChenMinjian , GuoXuejiang , WangQiang.  (2024)  The global phosphorylation landscape of mouse oocytes during meiotic maturation.  EMBO JOURNAL,      [PMID:39256562] [10.1038/s44318-024-00222-1]

33. Hongxin Zhang, Junxia Liu, Fred Mwabulili, Peng Li, Xiao Li, Yanli Xie, Yuhui Yang, Qian Li, Weibin Ma, Hang Jia, Yuan Tian.  (2025)  The expression, identification, and application of DsDDH: a dehydrogenase from Devosia sp. 63-57 for the biodegradation of deoxynivalenol.  Food Bioscience,      [PMID:] [10.1016/j.fbio.2025.107293]

34. Meichen Zhu, Qinzhe Lin, Mengning Zhong, Jian Dong, Leyi Zhao, Qiyun Wu, Huilin Ren, Wenting Du, Jun Li.  (2025)  Rational engineering of an imine reductase unlocks stereochemical gatekeeping for efficient synthesis of Evocalcet chiral intermediate.  Molecular Catalysis,      [PMID:] [10.1016/j.mcat.2025.115415]

35. Kunpeng Li, Rongzhen Zhang, Yan Xu, Zhimeng Wu, Jing Li, Xiaotian Zhou, Jiawei Jiang, Haiyan Liu, Rong Xiao.  (2017)  Sortase A-mediated crosslinked short-chain dehydrogenases/reductases as novel biocatalysts with improved thermostability and catalytic efficiency.  Scientific Reports,      [PMID:28596548] [10.1038/s41598-017-03168-z]

36. Rui Cai, Yahong Yuan, Zhouli Wang, Chunfeng Guo, Bin Liu, Laping Liu, Yutang Wang, Tianli Yue.  (2015)  Precursors and metabolic pathway for guaiacol production by Alicyclobacillus acidoterrestris.  INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY,      [PMID:26241489] [10.1016/j.ijfoodmicro.2015.07.028]

37. Yanyan Niu, Lisi Wang, Yuxue Chen, Juan Zhou, Wei Sun.  (2025)  Analysis of melatonin simulated metabolism based on electrochemistry coupled online with high performance liquid chromatography-mass spectrometry.  Analytical Methods,      [PMID:40424000] [10.1039/D5AY00110B]

38. Yu Du, Xiang Lv, Till Siebenmorgen, Grzegorz Popowicz, Chenhao Feng, Yunjian Ma, Yonghua Wang.  (2025)  Enhancing Catalytic Activity of a Baeyer–Villiger monooxygenase from Oceanicola granulosus: Simultaneous Engineering of the Distal Site and Active Site.  JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,      [PMID:40448641] [10.1021/acs.jafc.5c01791]

39. Hulin Qiu, Wenzhong Gong, Huilin Huang, Heng Guo, Zhizeng Gao, Lan Liu, Xinjian Yin.  (2025)  Rosetta-Driven Rapid Evolution of meso-Diaminopimelate Dehydrogenases for Structurally Diverse D-Amino Acid Production.  JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,      [PMID:40494826] [10.1021/acs.jafc.5c03073]

40. Yuhan Zhao, Xiaojie Zhou, Mei Li, Xinghui Qiu.  (2025)  Functional characterization of CYP9J26, a cytochrome P450 associated with insecticide resistance in the arbovirus vector Aedes albopictus.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:40533012] [10.1016/j.ijbiomac.2025.145280]

41. Kang Shaoyang, Ding Sheng, Lyu Donghao, Gao Rui, Peng Sirui, Liu Jing, Zhang Chuangnian, Feng Zujian, Huang Pingsheng, Kong Deling, Wang Weiwei.  (2025)  A Microgel-Stabilized, Light-Controlled Artificial Energy Supply Module for Efficient Biosynthesis.  Regenerative Biomaterials,      [PMID:41669165] [10.1093/rb/rbaf106]

42. Junzhu Yang, Junchen Liu, Yi Zhang, Wei Pei, Qi Xia, Sanyang Han, Yuan Lu.  (2025)  Photocatalytic NAD(P)H regeneration by alkali-doped g-C3N4 and extending visible light to near-infrared light.  CARBON,      [PMID:] [10.1016/j.carbon.2025.121140]

43. Arushi Mahajan, Meena Devi, Pallvi Mehra, Amarjeet Kaur, Sanehdeep Kaur.  (2025)  Impact of Chlorantraniliprole Exposure on Nutritional and Physiological Responses of Lab-Selected Susceptible and Resistant Populations of Spodoptera litura (Fabricius).  JOURNAL OF APPLIED ENTOMOLOGY,  149  (7): (1090-1104).  [PMID:] [10.1111/jen.13437]

44. Wenhao Hou, Qian Xu, Yuqing Niu, Yaqi Liu, Yun Ju, Jing He, Jie Jiang, Lina Qiao, Hongbin Xie, Hong Zhang.  (2026)  Regulating CO and CC reduction by positively charged ions in water microdroplets.  Journal of Environmental Chemical Engineering,  14  (1): (121009).  [PMID:] [10.1016/j.jece.2025.121009]

45. Yuxin Shen, Jun Wu, Lu Cao, Shiqi Jiang, Yan Chen, Ren-ai Xu, Ling Ji.  (2026)  Effects of Cytochrome P450 enzymes and drug–drug interaction on donafenib metabolism: in vivo, in vitro and in silico.  BIOORGANIC CHEMISTRY,      [PMID:41687527] [10.1016/j.bioorg.2026.109523]

46. Xiyuan Tang, Meiying Zhu, Zhipeng Liu, Longyu Zhang, Chengli Yang, Jian Zhang, Zhaohui Liu, Dali Li.  (2026)  One-pot preparation of magnetic cross-linked enzyme aggregates from a crude enzyme cocktail for cascaded catalytic production of biliverdin.  BIOCHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.bej.2026.110116]

47. Chao Xiang, Jia-Jia Mou, Yue Jiang, Yu-Ke Cen, Ya-Ping Xue, Yu-Guo Zheng.  (2026)  Design-informed construction of self-sufficient cytochrome P450 fusion enzymes for efficient avermectin oxidation.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:41763425] [10.1016/j.ijbiomac.2026.151151]