GRADE & PURITYRecombinant?Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin.Validated?Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated.ExactAb™?ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications.0.2 mg/mL
ExactAb™, Validated, Recombinant, 0.2 mg/mL ExactAb™,Recombinant,Validated for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping
Store at -20°C,Avoid repeated freezing and thawing Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
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Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Overview
Rabbit anti Human SET/TAF-I Antibody, Recombinant, could be used for WB, IHC, IF/ICC and so on. Application: WB: 1/500-1/1000 IHC: 1/50-1/100 IF/ICC: 1/50-1/200 Protein Function: Multitasking protein, involved in apoptosis, transcription, nucleosome assembly and histone binding. Isoform 2 anti-apoptotic activity is mediated by inhibition of the GZMA-activated DNase, NME1. In the course of cytotoxic T-lymphocyte (CTL)-induced apoptosis, GZMA cleaves SET, disrupting its binding to NME1 and releasing NME1 inhibition. Isoform 1 and isoform 2 are potent inhibitors of protein phosphatase 2A. Isoform 1 and isoform 2 inhibit EP300/CREBBP and PCAF-mediated acetylation of histones (HAT) and nucleosomes, most probably by masking the accessibility of lysines of histones to the acetylases. The predominant target for inhibition is histone H4. HAT inhibition leads to silencing of HAT-dependent transcription and prevents active demethylation of DNA. Both isoforms stimulate DNA replication of the adenovirus genome complexed with viral core proteins; however, isoform 2 specific activity is higher.
Specifications
Product Name
Recombinant SET/TAF-I Antibody - Primary antibody, specific to SET, Rabbit IgG
Synonyms
2PP2A | IGAAD | MRD58 | TAF-I | I2PP2A | IPP2A2 | PHAPII | TAF-IBETA | SET | 2PP2A antibody | HLA DR associated protein II antibody | HLA-DR-associated protein II antibody | I 2PP2A antibody | I-2PP2A antibody | I2PP2A antibody | IGAAD antibody | Inhibito
Specifications & Purity
ExactAb™, Validated, Recombinant, 0.2 mg/mL
Host species
Rabbit
Specificity
SET
Immunogen
A synthetic peptide derived from human SET (AA 217-230).
Positive Control
WB: K562, HeLa, MCF7, Hep G2, NIH/3T3 and C6 cell lysates. IHC: Human lung cancer tissue. IF/ICC: HeLa cells.
Conjugation
Unconjugated
Grade
ExactAb™, Recombinant, Validated
Isotype
Rabbit IgG
SDS-PAGE
150 kDa
Purification Method
Antigen Affinity Purified
Concentration
0.2 mg/mL
Storage and Shipping
Shape
Liquid
Storage
Store at -20°C,Avoid repeated freezing and thawing
Shipped In
Ice chest + Ice pads
Stability And Storage
Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
Images
Recombinant SET/TAF-I Antibody (Ab127229) - Western Blot All lanes: Recombinant SET/TAF-I Antibody (Ab127229) at 1/1000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 33 kDa Observed band size: 38, 34 kDa Recombinant SET/TAF-I Antibody (Ab127229) recognizes different isoforms of human SET/TAF-I. Exposure time: 4.9 s
Recombinant SET/TAF-I Antibody (Ab127229) - IHC Immunohistochemistry analysis of paraffin-embedded Human lung cancer using Recombinant SET/TAF-I Antibody (Ab127229). Highpressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
Recombinant SET/TAF-I Antibody (Ab127229) - IF/ICC Immunocytochemistry analysis of SET(green) in HeLa using Recombinant SET/TAF-I Antibody (Ab127229), and DAPI(blue).
Application
Application
Dilution info
IHC
1/50 - 1/100
IF/ICC
1/50 - 1/200
WB
1/500-1/1000
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
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