≥99% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Room temperature Ships Normal Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 4 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
TAPS is a zwitterionic buffer used in biochemistry and molecular biology. It has a useful pH range of 7.7 - 9.1. TAPS has been utilized in capillary electrophoresis of DNA and DNA-dye complexes. Dyes can be separated by planar chromatography with electroosmotic flow containing 1 mM TAPS in the mobile phase. The stability constants of metal ions with TAPS have been investigated through the use of capillary electrophoresis. TAPS has also been shown to inhibit the activity of connexin channels. The activity of various carbonic anhydrases has been studied using TAPS physiological buffer, pKa = 8.4 at 20° C.
| Canonical Smiles | C(CNC(CO)(CO)CO)CS(=O)(=O)O |
|---|---|
| IUPAC Name | 3-[[1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl]amino]propane-1-sulfonic acid |
| InChIKey | YNLCVAQJIKOXER-UHFFFAOYSA-N |
| INCHI | 1S/C7H17NO6S/c9-4-7(5-10,6-11)8-2-1-3-15(12,13)14/h8-11H,1-6H2,(H,12,13,14) |
| Isomeric SMILES | C(CNC(CO)(CO)CO)CS(=O)(=O)O |
| WGK Germany | 3 |
| PubChem CID | 121591 |
| Molecular Weight | 243.28 |
| Beilstein | 2452420 |
| Reaxy-Rn | 2452420 |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organic acids and derivatives |
| Class | Organic sulfonic acids and derivatives |
| Subclass | Organosulfonic acids and derivatives |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Organosulfonic acids |
| Alternative Parents | Sulfonyls Alkanesulfonic acids 1,2-aminoalcohols Dialkylamines Primary alcohols Organopnictogen compounds Organic oxides Hydrocarbon derivatives |
| Molecular Framework | Aliphatic acyclic compounds |
| Substituents | Organosulfonic acid - Sulfonyl - Alkanesulfonic acid - 1,2-aminoalcohol - Secondary aliphatic amine - Secondary amine - Organopnictogen compound - Organic oxygen compound - Alcohol - Primary alcohol - Organosulfur compound - Organooxygen compound - Organonitrogen compound - Organic nitrogen compound - Amine - Organic oxide - Hydrocarbon derivative - Aliphatic acyclic compound |
| Description | This compound belongs to the class of organic compounds known as organosulfonic acids. These are compounds containing the sulfonic acid group, which has the general structure RS(=O)2OH (R is not a hydrogen atom). |
| External Descriptors | Not available |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 K2120544 | Certificate of Analysis | Sep 04, 2025 | T108961 |
| K2120553 | Certificate of Analysis | Sep 04, 2025 | T108961 |
| F2505011 | Certificate of Analysis | Jun 17, 2025 | T108961 |
| F2505012 | Certificate of Analysis | Jun 13, 2025 | T108961 |
| F2116225 | Certificate of Analysis | Mar 04, 2025 | T108961 |
| F2116378 | Certificate of Analysis | Mar 04, 2025 | T108961 |
| F2116379 | Certificate of Analysis | Mar 04, 2025 | T108961 |
| C2526533 | Certificate of Analysis | Jun 18, 2024 | T108961 |
| L2424586 | Certificate of Analysis | Jun 18, 2024 | T108961 |
| D2530360 | Certificate of Analysis | Jun 18, 2024 | T108961 |
| D2530361 | Certificate of Analysis | Jun 18, 2024 | T108961 |
| E2530116 | Certificate of Analysis | Sep 23, 2022 | T108961 |
| I2220589 | Certificate of Analysis | Sep 23, 2022 | T108961 |
| I2220602 | Certificate of Analysis | Sep 23, 2022 | T108961 |
| I2403039 | Certificate of Analysis | Sep 23, 2022 | T108961 |
| Flash Point(°F) | >230 ℉ |
|---|---|
| Flash Point(°C) | >110°C |
| Melt Point(°C) | 230-235°C |
| Molecular Weight | 243.280 g/mol |
| XLogP3 | -5.400 |
| Hydrogen Bond Donor Count | 5 |
| Hydrogen Bond Acceptor Count | 7 |
| Rotatable Bond Count | 8 |
| Exact Mass | 243.078 Da |
| Monoisotopic Mass | 243.078 Da |
| Topological Polar Surface Area | 135.000 Ų |
| Heavy Atom Count | 15 |
| Formal Charge | 0 |
| Complexity | 247.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
| 1. Yuting Li, Luhan Wang, Minhua Qian, Shengda Qi, Lei Zhou, Qiaosheng Pu. (2022) Concise analysis of γ-hydroxybutyric acid in beverages and urine by capillary electrophoresis with capacitively coupled contactless conductivity detection using 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid as background electrolyte. JOURNAL OF CHROMATOGRAPHY A, [PMID:35675730] [10.1016/j.chroma.2022.463191] |
| 2. Liye Yang, Guangchao Pan, Piwang Zhang, Qiang Liu, Xing Liu, Yan Li, Ying Liang, Min Zhang. (2021) 3D printed two-in-one on-capillary detector: Combining contactless conductometric and photometric detection for capillary electrophoresis. ANALYTICA CHIMICA ACTA, [PMID:33867034] [10.1016/j.aca.2021.338427] |
| 3. Wang Chen, Wang Qian, Li Shuangsi, Zhang Man, Zhao Weifeng, Sun Shudong, Zhao Changsheng. (2017) One-pot synthesis of highly hemocompatible polyurethane/polyethersulfone composite membranes. POLYMER BULLETIN, 74 (9): (3797-3818). [PMID:] [10.1007/s00289-017-1922-5] |
| 4. Rui Zhao, Xiangjian Liu, Marlene Davis Ekpo, Yongju He, Songwen Tan. (2024) Exploring the Cryopreservation Mechanism and Direct Removal Strategy of TAPS in Red Blood Cell Cryopreservation. ACS Biomaterials Science & Engineering, [PMID:38832439] [10.1021/acsbiomaterials.3c01701] |
