Cannabinoid Receptor I Antibody - Primary antibody, specific to CNR1, Rabbit IgG

Cat. No.: Ab092707

GRADE & PURITY Validated, ExactAb™, 1.0 mg/mL

Application

IF/ICC, IHC, WB

Host species

Rabbit

Reactive species

Human, Monkey, Mouse, Rat

Isotype

Rabbit IgG

Conjugation

Unconjugated

Overview

Rabbit anti Human Cannabinoid Receptor I Antibody, Polyclonal, could be used for WB, IHC, IF/ICC and so on.

Specifications

Product Name

Cannabinoid Receptor I Antibody - Primary antibody, specific to CNR1, Rabbit IgG

Synonyms

CANN6 | CANN6CB1R | Cannabinoid R1 | cannabinoid receptor 1 (brain) | CannabinoidR1 | CB1 | CB1A | CB1K5 | CB1R | CB-R | CB-RCB1cannabinoid receptor 1 | central cannabinoid receptor | CNR | CNR1 | SKR6R | CANN6 antibody | Cannabinoid receptor 1 antibody |

Specifications & Purity

Validated, ExactAb™, 1.0 mg/mL

Biochemical and Physiological Mechanisms

Involved in cannabinoid-induced CNS effects. Acts by inhibiting adenylate cyclase. Could be a receptor for anandamide. Inhibits L-type Ca(2+) channel current. Isoform 2 and isoform 3 have altered ligand binding.

Host species

Rabbit

Specificity

CNR1

Immunogen

A synthetic peptide derived from human Cannabinoid Receptor I (AA 151-200).

Positive Control

WB: Rat brain, HT-29 lysates. IHC: Human brain tissue. IF/ICC: LOVO cells.

Conjugation

Unconjugated

Grade

ExactAb™, Validated

Isotype

Rabbit IgG

SDS-PAGE

150 kDa

Purification Method

Immunogen affinity purified

Concentration

1.0 mg/mL

Storage and Shipping

Shape

Liquid

Storage

Store at -20°C,Avoid repeated freezing and thawing

Shipped In

Ice chest + Ice pads

Stability And Storage

Store at 2-8℃ short term (1-2 weeks). Store at -20℃ long term (12 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Images

Western Blot: Cannabinoid Receptor I Antibody (Ab092707)

Cannabinoid Receptor I Antibody (Ab092707) - Western Blot
All lanes: Cannabinoid Receptor I Antibody (Ab092707) at 1/2000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution

Predicted band size: 53 kDa
Observed band size: 49 kDa
Exposure time: 130.0 s

Western Blot: Cannabinoid Receptor I Antibody (Ab092707)

Cannabinoid Receptor I Antibody (Ab092707) - Western Blot
All lanes: Cannabinoid Receptor I Antibody (Ab092707) at 1/2000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution

Predicted band size: 53 kDa
Observed band size: 49 kDa
Exposure time: 130.0 s

IHC: Cannabinoid Receptor I Antibody (Ab092707)

Cannabinoid Receptor I Antibody (Ab092707) - IHC
Immunohistochemistry analysis of paraffin-embedded human brain tissue, using Cannabinoid Receptor I Antibody (Ab092707). The picture on the right is blocked with the synthesized peptide.

IF/ICC: Cannabinoid Receptor I Antibody (Ab092707)

Cannabinoid Receptor I Antibody (Ab092707) - IF/ICC
Immunofluorescence analysis of LOVO cells, using Cannabinoid Receptor I Antibody (Ab092707). The picture on the right is blocked with the synthesized peptide.

Application

• Application: Dilution info
• WB:

  1/500-1/2000;

• IHC:

  1/100-1/300

• IF/ICC:

  1/200-1/1000;

Associated Targets(Human)

CNR1 Tclin Cannabinoid receptor 1 (0 Activities)

Discover Target: CNR1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CNR1 Tclin Cannabinoid CB1 receptor (20913 Activities)

Discover Target: CNR1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CNR1 Tclin Cannabinoid CB1 receptor/orexin receptor 1 complex (18 Activities)

Discover Target: CNR1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action