DL-Mandelic acid - ≥99% , CAS No.611-72-3

CAS: 611-72-3 Cat. No.: D304135 Molecular Weight: 152.15 EC Number: 210-277-1
AVAILABLE TO ORDER
GRADE & PURITY ≥99%
Synonyms
s3363 | (+/-)-alpha-Hydroxybenzeneacetic acid | alpha-Hydroxybenzeneacetic acid | (.+/-.)-Mandelic acid | CHEBI:35825 | EINECS 202-007-6 | MANDELIC ACID | Phenylacetic acid, alpha-hydroxy- | acidomandelico | hyroxyphenylacetic acid | Kyselina mandlova | U
Storage
Room temperature,Desiccated
Shipped In
Normal
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Size
Status
Price
Qty
25g
D304135-25g
7
$36.90
100g
D304135-100g
2
$101.90
Enter a quantity for the sizes you want to add.
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Why this grade

≥99% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Room temperature,Desiccated Ships Normal Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 31 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Synonyms
s3363 | (+/-)-alpha-Hydroxybenzeneacetic acid | alpha-Hydroxybenzeneacetic acid | (.+/-.)-Mandelic acid | CHEBI:35825 | EINECS 202-007-6 | MANDELIC ACID | Phenylacetic acid, alpha-hydroxy- | acidomandelico | hyroxyphenylacetic acid | Kyselina mandlova | U
Specifications & Purity
≥99%
Storage
Room temperature, Desiccated
Shipped In
Normal
Purity
≥99%
Names and Identifiers
Pubchem Sid504750482
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/504750482
Canonical SmilesC1=CC=C(C=C1)C(C(=O)O)O
IUPAC Name2-hydroxy-2-phenylacetic acid
InChIKeyIWYDHOAUDWTVEP-UHFFFAOYSA-N
INCHI1S/C8H8O3/c9-7(8(10)11)6-4-2-1-3-5-6/h1-5,7,9H,(H,10,11)
Isomeric SMILES C1=CC=C(C=C1)C(C(=O)O)O
Molecular Weight 152.15
Reaxy-Rn 510011
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=510011&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

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🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassBenzenoids
ClassBenzene and substituted derivatives
SubclassNot available
Intermediate Tree Nodes Not available
Direct ParentBenzene and substituted derivatives
Alternative Parents Alpha hydroxy acids and derivatives  Secondary alcohols  Monocarboxylic acids and derivatives  Carboxylic acids  Organic oxides  Hydrocarbon derivatives  Carbonyl compounds  Aromatic alcohols  
Molecular FrameworkAromatic homomonocyclic compounds
Substituents Hydroxy acid - Monocyclic benzene moiety - Alpha-hydroxy acid - Secondary alcohol - Monocarboxylic acid or derivatives - Carboxylic acid - Carboxylic acid derivative - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Aromatic alcohol - Organooxygen compound - Carbonyl group - Alcohol - Aromatic homomonocyclic compound
DescriptionThis compound belongs to the class of organic compounds known as benzene and substituted derivatives. These are aromatic compounds containing one monocyclic ring system consisting of benzene.
External Descriptors benzenes - 2-hydroxy monocarboxylic acid
3D Structure
Interactive Chemical Structure Model





Associated Targets(Human)
PTPN7 Tchem Protein-tyrosine phosphatase LC-PTP (886 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GAPDH Tchem Glyceraldehyde-3-phosphate dehydrogenase liver (1284 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HepG2 (196354 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC16A1 Tchem Monocarboxylate transporter 1 (146 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
IDO1 Tchem Indoleamine 2,3-dioxygenase (6650 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
POLK Tbio DNA polymerase kappa (8653 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HSPA1A Tchem Heat shock 70 kDa protein 1 (164 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KDM4A Tchem Lysine-specific demethylase 4A (52245 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
LMNA Tbio Prelamin-A/C (36751 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC16A7 Tchem Monocarboxylate transporter 2 (11 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
OPM-2 (216 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Associated Targets(non-human)
ampC Beta-lactamase AmpC (62480 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
blaZ Beta-lactamase (285 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HD1 Histone deacetylase (38 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Plasmodium falciparum (966862 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Dusp6 Dual specificity protein phosphatase 6 (459 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Txnrd1 Thioredoxin reductase 1, cytoplasmic (45279 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HSPA8 Heat shock cognate 71 kDa protein (1 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

5 results found

Lot NumberCertificate TypeDateItem
D2307461Certificate of AnalysisJan 21, 2026 D304135
K2224227Certificate of AnalysisSep 04, 2025 D304135
C2125239Certificate of AnalysisJan 02, 2024 D304135
C2125241Certificate of AnalysisJan 02, 2024 D304135
C2125240Certificate of AnalysisNov 30, 2022 D304135
Chemical and Physical Properties
Flash Point(°C)162.6ºC
Boil Point(°C)321.8ºC
Melt Point(°C)120-122ºC
Molecular Weight152.150 g/mol
XLogP30.600
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count3
Rotatable Bond Count2
Exact Mass152.047 Da
Monoisotopic Mass152.047 Da
Topological Polar Surface Area57.500 Ų
Heavy Atom Count11
Formal Charge0
Complexity138.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Documents & Articles
Citations of This Product
References
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2. Xin Qiu, Wenbei Chen, Yuting Chen, Jian Ke, Yibing Ji, Jianqiu Chen.  (2023)  Separation of chiral drugs through dual chiral ionic liquid functionalized composite membrane and study on chiral recognition mechanism.  JOURNAL OF MEMBRANE SCIENCE,      [PMID:] [10.1016/j.memsci.2023.122087]
3. Rongxiu Qin, Haiyan Chen, Rusi Wen, Guiqing Li, Zhonglei Meng.  (2023)  Effect of Boric Acid on the Ionization Equilibrium of α-Hydroxy Carboxylic Acids and the Study of Its Applications.  MOLECULES,  28  (12): (4723).  [PMID:37375278] [10.3390/molecules28124723]
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5. Kui Kang, Mengyi Zhang, Lei Yue, Weiwen Chen, Yangshuo Dai, Kai Lin, Kai Liu, Jun Lv, Zhanwen Guan, Shi Xiao, Wenqing Zhang.  (2023)  Oxalic Acid Inhibits Feeding Behavior of the Brown Planthopper via Binding to Gustatory Receptor Gr23a.  Cells,  12  (5): (771).  [PMID:36899907] [10.3390/cells12050771]
6. Zhong-Lei Meng, Rong-Xiu Qin, Ru-Si Wen, Gui-Qing Li, Zhong-Yun Liang, Jun-Kang Xie, Yong-Hong Zhou, Zhang-Qi Yang.  (2023)  Study on Synthesizing Isobornyl Acetate/Isoborneol from Camphene Using α-Hydroxyl Carboxylic Acid Composite Catalyst.  MOLECULES,  28  (4): (1875).  [PMID:36838861] [10.3390/molecules28041875]
7. Yongjing Liu, Suxia Zhang, Li Lou, Tang Yan, Wei Xu.  (2022)  Evaluating the behavior and principle of deep eutectic solvent on ephedrine-type alkaloid extraction from Ephedrae Herba.  BIOMEDICAL CHROMATOGRAPHY,  37  (2): (e5541).  [PMID:36328792] [10.1002/bmc.5541]
8. Jiahong Guo, Xiaoyu Ma, Fernando Bouffard, Sophia Yi Zhang.  (2022)  A Novel multi-fruit acids formula design on molecular basis for skin brightening via a system biology approach.  Journal of Cosmetic Dermatology,  21  (11): (6145-6155).  [PMID:35713107] [10.1111/jocd.15163]
9. Yu Fu, Xingchong Liu, Shuangshuang Zhao.  (2022)  Mandelic Acid as an Interfacial Modifier for High Performance NiOx-based Inverted Perovskite Solar Cells.  ChemNanoMat,  (7): (e202200091).  [PMID:] [10.1002/cnma.202200091]
10. Xiaohui Niu, Simeng Yan, Jinliang Chen, Hongxia Li, Kunjie Wang.  (2022)  Enantioselective recognition of L/D-amino acids in the chiral nanochannels of a metal-organic framework.  ELECTROCHIMICA ACTA,      [PMID:] [10.1016/j.electacta.2021.139809]
11. Huan Luo, Xiaoping Bai, Huixian Liu, Xin Qiu, Jianqiu Chen, Yibing Ji.  (2021)  β-Cyclodextrin covalent organic framework modified-cellulose acetate membranes for enantioseparation of chiral drugs.  SEPARATION AND PURIFICATION TECHNOLOGY,      [PMID:] [10.1016/j.seppur.2021.120336]
12. Yongjing Liu, Qiang Chen, Suxia Zhang, Hua Zhang, Wei Xu.  (2021)  Evaluation of green and efficient deep eutectic solvents as media for extracting alkaloids from lotus leaf.  BIOMEDICAL CHROMATOGRAPHY,  36  (3): (e5293).  [PMID:34873711] [10.1002/bmc.5293]
13. Mingyu Liu, Zhixing Lai, Lijun Zhu, Xin Ding, Xiyang Tong, Zhen Wang, Qirui Bi, Ninghua Tan.  (2021)  Novel amorphous solid dispersion based on natural deep eutectic solvent for enhancing delivery of anti-tumor RA-XII by oral administration in rats.  EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES,      [PMID:34256100] [10.1016/j.ejps.2021.105931]
14. Qiang Huang, Yu Tao, Huichang Li, Lihua Guo, Liye Wang, Chunlan Ban, Guopeng Shen.  (2021)  (R,S)-Mandelic acid in pure and binary solvents solubility measurement and its correlation with thermodynamic models.  JOURNAL OF MOLECULAR LIQUIDS,      [PMID:] [10.1016/j.molliq.2021.116768]
15. Xueqin Wang, Jinguo Jiang, Qingqing Zhang, Zhongchen Bai.  (2021)  The high active SERs substrate prepared by self assembling Ag nanoparticles on PPy@PEDOT:PSS film to detect the sodium formaldehyde sulfoxylate molecules.  OPTICAL MATERIALS,      [PMID:] [10.1016/j.optmat.2021.110955]
16. Hong-Yan Wang, Yu-Li Xie, Xin Shi, Hong-Ling Shi, Jian-He Xu, Cun-Duo Tang, Lun-Guang Yao, Yun-Chao Kan.  (2020)  Directed evolution of a D-mandelate dehydrogenase toward D-o-chloromandelic acid and insight into the molecular basis for its catalytic performance.  BIOCHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.bej.2020.107863]
17. He Song, Chang Mengyu, Liu Pengcheng, Wang Xueqin, Bai Zhongchen.  (2020)  Self-assembled deposition of Ag nano-particles on PPy@PEDOT:PSS films to detect melamine molecules.  APPLIED PHYSICS A-MATERIALS SCIENCE & PROCESSING,  126  (12): (1-7).  [PMID:] [10.1007/s00339-020-04130-z]
18. Dongxiu Wang, Pengxia Li, Junfen Li, Chuan Dong.  (2020)  An efficient fluorescent nano-sensor of N-doped carbon dots for the determination of 2,4,6-trinitrophenol and other applications.  Analytical Methods,  12  (43): (5195-5201).  [PMID:33090130] [10.1039/D0AY01702G]
19. Cun-Duo Tang, Hong-Ling Shi, Yuan-Yuan Jia, Xiang Li, Lin-Feng Wang, Jian-He Xu, Lun-Guang Yao, Yun-Chao Kan.  (2020)  High level and enantioselective production of L-phenylglycine from racemic mandelic acid by engineered Escherichia coli using response surface methodology.  ENZYME AND MICROBIAL TECHNOLOGY,      [PMID:32331718] [10.1016/j.enzmictec.2020.109513]
20. Cun-Duo Tang, Peng-Ju Ding, Hong-Ling Shi, Yuan-yuan Jia, Mao-zhi Zhou, Hui-lei Yu, Jian-He Xu, Lun-Guang Yao, Yun-Chao Kan.  (2019)  One-Pot Synthesis of Phenylglyoxylic Acid from Racemic Mandelic Acids via Cascade Biocatalysis.  JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,      [PMID:30807132] [10.1021/acs.jafc.8b07295]
21. Jun Sang, Kang Liu, Qun Ma, Bing Li, Cui-qin Li.  (2018)  Combination of a deep eutectic solvent and macroporous resin for green recovery of anthocyanins from Nitraria tangutorun Bobr. fruit.  SEPARATION SCIENCE AND TECHNOLOGY,      [PMID:] [10.1080/01496395.2018.1559190]
22. Datong Wu, Wensheng Tan, Yin Yu, Baozhu Yang, Hongda Li, Yong Kong.  (2018)  A facile avenue to prepare chiral graphene sheets as electrode modification for electrochemical enantiorecognition.  ANALYTICA CHIMICA ACTA,      [PMID:30172332] [10.1016/j.aca.2018.06.029]
23. Cun-Duo Tang, Hong-Ling Shi, Jian-He Xu, Zhu-Jin Jiao, Fei Liu, Peng-Ju Ding, Hong-Fei Shi, Lun-Guang Yao, Yun-Chao Kan.  (2018)  Biosynthesis of Phenylglyoxylic Acid by LhDMDH, a Novel d-Mandelate Dehydrogenase with High Catalytic Activity.  JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,      [PMID:29460618] [10.1021/acs.jafc.7b05835]
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