Epcoritamab (anti-CD3&CD20) - Primary antibody, specific to CD3E & MS4A1, Human IgG1, Antibody of CD20 (membrane-spanning 4-domains; subfamily A; member 1);Antibody of CD3e, Antibody of CD20 (membrane-spanning 4-domains; subfamily A; member 1);Antibody of CD3e

CAS: 2134641-34-0 Cat. No.: Ab175531
AVAILABLE TO ORDER
GRADE & PURITY Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. ≥90%(SDS-PAGE&SEC-HPLC) See COA
Application
Animal Model, ELISA, Flow Cytometry, Functional Assay
Host species
Human
Reactive species
Cynomolgus monkey, Human
Isotype
Human IgG1
Conjugation
Unconjugated
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
100μg
Ab175531-100μg
5
$247.90
1mg
Ab175531-1mg
2
$1,239.90
5mg
Ab175531-5mg
1
$3,099.90
10mg
Ab175531-10mg
1-2 wks(?)
Item is derived from our semi-finished stock and is processed in 1-2 weeks.
$4,959.90
Enter a quantity for the sizes you want to add.
🧪

Why this grade

Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥90%(SDS-PAGE&SEC-HPLC), See COA Animal Free,Azide Free,Carrier Free,ExactAb™,Low Endotoxin,Recombinant,Validated for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -80°C,Avoid repeated freezing and thawing Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

Epcoritamab (anti-CD3 & CD20) is an bispecific IgG1 antibody redirecting T-cells toward CD3×CD20+ tumor cells. Epcoritamab (anti-CD3 & CD20) induces potent T-cell-mediated cytotoxicity towards B-cell NHL cell lines.

Specifications

Product Name
Epcoritamab (anti-CD3&CD20) - Primary antibody, specific to CD3E & MS4A1, Human IgG1, Antibody of CD20 (membrane-spanning 4-domains; subfamily A; member 1);Antibody of CD3e
Synonyms
CD3 epsilon antibody | CD3e antibody | CD3e antigen antibody | CD3e antigen epsilon polypeptide (TiT3 complex) antibody | CD3E antigen epsilon polypeptide antibody | CD3E antigen, epsilon subunit antibody | CD3e molecule epsilon antibody | CD3e molecule,
Specifications & Purity
Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥90%(SDS-PAGE&SEC-HPLC), See COA
Biochemical and Physiological Mechanisms
CD3: The CD3 complex mediates signal transduction. CD20: This protein may be involved in the regulation of B-cell activation and proliferation.
Host species
Human
Specificity
CD3E & MS4A1
Conjugation
Unconjugated
Grade
Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Action Type
BINDING AGENT
Mechanism of action
Antibody of CD20 (membrane-spanning 4-domains; subfamily A; member 1);Antibody of CD3e
Isotype
Human IgG1
Light Chain Type
kappa - lambda
SDS-PAGE
146.28 kDa
Purification Method
Protein A purified
Concentration
See COA
CAS
2134641-34-0
Storage and Shipping
Storage
Store at -80°C,Avoid repeated freezing and thawing
Shipped In
Dry ice packs + Cold packs
Stability And Storage
Store at -80℃ for 24 months. Upon delivery aliquot. Avoid freeze/thaw cycle.
Images

Epcoritamab (anti-CD3&CD20) (Ab175531) - Flow Cytometry
Flow Cytometry analysis of Raji cells labelling CD3&CD20 (red) with Epcoritamab (anti-CD3&CD20) (Ab175531) at 1.0 μg/mL for 1 hour at 4°C. Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

Epcoritamab (anti-CD3&CD20) (Ab175531) - ELISA
Immobilized Recombinant Human CD3 epsilon protein (rp175910) at 1.0 μg/mL can bind Epcoritamab (anti-CD3&CD20) (Ab175531) with the EC₅₀ of 39.7 ng/mL.

Epcoritamab (anti-CD3&CD20) (Ab175531) - SEC
The purity of Epcoritamab (anti-CD3&CD20) (Ab175531) is more than 95% verified by HPLC.

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Associated Targets(Human)
MS4A1 Tclin B-lymphocyte antigen CD20 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CD3E Tclin T-cell surface glycoprotein CD3 epsilon chain (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
MS4A1 Tclin B-lymphocyte antigen CD20 (0 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CD3E Tclin T-cell surface glycoprotein CD3 epsilon chain (0 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Documents & Articles
Solution Calculators
Reviews

Customer Reviews

Need help choosing the grade?

Our grade selection guide covers purity, stabilizer status, and application suitability for all variants in our catalog.

View Animal Free grade guide → View Carrier Free grade guide → View Recombinant grade guide → View Validated grade guide → View ExactAb™ grade guide → View Low Endotoxin grade guide → View Azide Free grade guide →

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