Recombinant HDAC2 Antibody - Primary antibody, specific to HDAC2, Rabbit IgG

Cat. No.: Ab107031
AVAILABLE TO ORDER
GRADE & PURITY Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. 0.6 mg/mL
Application
IF/ICC, IHC, WB
Host species
Rabbit
Reactive species
Human, Mouse, Rat
Isotype
Rabbit IgG
Conjugation
Unconjugated
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
10μl
Ab107031-10μl
2
$66.90
50μl
Ab107031-50μl
1
$259.90
Enter a quantity for the sizes you want to add.
🧪

Why this grade

ExactAb™, Validated, Recombinant, 0.6 mg/mL ExactAb™,Recombinant,Validated for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -20°C,Avoid repeated freezing and thawing Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 1 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

Rabbit anti Human HDAC2 Antibody, Recombinant, could be used for WB, IHC, IF, ICC and so on.

Application:
WB: 1/500-1/1000
IHC: 1/50-1/100
IF/ICC: 1/50-1/200
Protein Function:
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Forms transcriptional repressor complexes by associating with MAD, SIN3, YY1 and N-COR. Interacts in the late S-phase of DNA-replication with DNMT1 in the other transcriptional repressor complex composed of DNMT1, DMAP1, PCNA, CAF1. Deacetylates TSHZ3 and regulates its transcriptional repressor activity.

Specifications

Product Name
Recombinant HDAC2 Antibody - Primary antibody, specific to HDAC2, Rabbit IgG
Synonyms
EC 3.5.1.98 | HD2 | HDAC2 | Histone Deacetylase 2 | RPD3 | transcriptional regulator homolog RPD3 | YAF1 | YY1-associated factor 1 | D10Wsu179e antibody | HD 2 antibody | HD2 antibody | HDAC 2 antibody | Hdac2 antibody | HDAC2_HUMAN antibody | OTTHUMP0000
Specifications & Purity
ExactAb™, Validated, Recombinant, 0.6 mg/mL
Host species
Rabbit
Specificity
HDAC2
Immunogen
Recombinant protein of human HDAC2 (AA 339-488).
Positive Control
WB: HEK293, K562, A431, MCF7 and C6 cell lysates. IHC: Human colon cancer tissue. IF/ICC: HeLa sells.
Conjugation
Unconjugated
Grade
ExactAb™, Recombinant, Validated
Isotype
Rabbit IgG
SDS-PAGE
150 kDa
Purification Method
Antigen affinity purified
Concentration
0.6 mg/mL
Note
This product is about to be sold out and removed from the shelves. The alternative product is Ab107032.
Storage and Shipping
Shape
Liquid
Storage
Store at -20°C,Avoid repeated freezing and thawing
Shipped In
Ice chest + Ice pads
Stability And Storage
Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
Images

Recombinant HDAC2 Antibody (Ab107031) - Western Blot
All lanes: Recombinant HDAC2 Antibody (Ab107031) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/30000 dilution

Predicted band size: 55 kDa
Observed band size: 60 kDa
Exposure time: 5.0 s

Recombinant HDAC2 Antibody (Ab107031) - Western Blot
All lanes: Recombinant HDAC2 Antibody (Ab107031) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/30000 dilution

Predicted band size: 55 kDa
Observed band size: 60 kDa
Exposure time: 29.1 s

Recombinant HDAC2 Antibody (Ab107031) - IF/ICC
Immunocytochemistry analysis of HDAC2 (green) in HeLa using Recombinant HDAC2 Antibody (Ab107031), and cells were counterstained with DAPI (blue).


Recombinant HDAC2 Antibody (Ab107031) - IHC
Immunohistochemistry analysis of paraffin-embedded Human colon cancer using Recombinant HDAC2 Antibody (Ab107031). High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Application
ApplicationDilution info
WB

1/500-1/1000

IHC

1/50 - 1/100

IF/ICC

1/50 - 1/200

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Associated Targets(Human)
HDAC2 Tclin Histone deacetylase 2 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
HDAC2 Tclin Histone deacetylase 2 (3971 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HDAC2 Tclin Histone deacetylase 2/Nuclear receptor corepressor 2 (6 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HDAC2 Tclin Cereblon/Histone deacetylase 2 (7 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot NumberCertificate TypeDateItem
ZJ24F0202826Certificate of AnalysisFeb 23, 2024 Ab107031
ZJ24F0202827Certificate of AnalysisFeb 23, 2024 Ab107031
Documents & Articles
Citations of This Product
References
1. Yong Ling, Yangyang Li, Rui Zhu, Jianqiang Qian, Ji Liu, Weijie Gao, Chi Meng, Jiefei Miao, Biao Xiong, Xiaodong Qiu, Changchun Ling, Hong Dai, Yanan Zhang.  (2019)  Hydroxamic Acid Derivatives of β-Carboline/Hydroxycinnamic Acid Hybrids Inducing Apoptosis and Autophagy through the PI3K/Akt/mTOR Pathways.  JOURNAL OF NATURAL PRODUCTS,      [PMID:31120744] [10.1021/acs.jnatprod.8b00843]
Solution Calculators
Reviews

Customer Reviews

Need help choosing the grade?

Our grade selection guide covers purity, stabilizer status, and application suitability for all variants in our catalog.

View Recombinant grade guide → View Validated grade guide → View ExactAb™ grade guide →

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